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PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
منشور في 2019"…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …"
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82
SynergyGrids: blockchain-supported distributed microgrid energy trading
منشور في 2022"…The trading system shows 17.8% decrease in energy cost for consumers and 76.4% decrease in load over utility grids when compared with its counterparts.…"
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83
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Peripherally injected cholecystokinin-induced neuronal activation is modified by dietary composition in mice
منشور في 2010"…When comparing diet effects, while the HF diet did not induce any change in activity, reductions in MEMRI-associated signal were found in the paraventricular nucleus (PVN) and lateral hypothalamic area (LHA) when comparing the HP to the HC diet. …"
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85
The Potential Role of Daucus carota Aqueous and Methanolic Extracts on Inflammation and Gastric Ulcers in Rats
منشور في 2009"…DCAE intake (250 mg/kg body weight) for one month period did not show adverse effects on lipemia, glycemia, hepatic and liver function except for a slight decrease in HDL cholesterol (p<0.05). …"
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86
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The Impact of a Computerized Potassium Alert on Adverse Drug Events and Pharmacists' Interventions
منشور في 2010"…Methods: An alert was built into the pharmacy computer system, which warned pharmacists about a potassium level greater than 5.1 mEq/L when processing an order that could increase potassium. …"
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89
Rebound effects undermine carbon footprint reduction potential of autonomous electric vehicles
منشور في 2023"…<p dir="ltr">Autonomous vehicles offer greater passenger convenience and improved fuel efficiency. …"
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90
An investigation into links between UAE STI Policy and the Federal Universities STEM Majors’ Enrolments, Graduates and Research Development: an evidence-based exploration of the im...
منشور في 2020"…Zayed University-Dubai had greater STEM majors’ enrolments compared to Zayed University-Abu Dhabi. …"
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91
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92
Phenotypic and Genotypic Characterization of Candida parapsilosis complex isolates from a Lebanese Hospital
منشور في 2023"…The azole fluconazole is the first line of defense in hospital treatment. Azoles function by inhibiting ERG11, an enzyme involved in the synthesis of ergosterol, the main sterol found in fungi. …"
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masterThesis -
93
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Sternbergia Clusiana Bulb Ethanolic Extracts Induce Apoptosis in MCF-7 Breast Cancer Cells
منشور في 2022"…The present study explores the anti-cancer activity of the ethanolic extract of Sternbergia clusiana bulbs (SbBEE) on breast cancer MCF-7 cell line in vitro and deciphers the underlying molecular mechanism associated with it. …"
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masterThesis -
95
Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
منشور في 2023"…</p><h3>Conclusion</h3><p dir="ltr">To our knowledge this is the first report of the stable non-lethal increase of SLFN11 expression in a cancer cell line. …"
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Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors
منشور في 2024"…Upon differentiating iPSCs lacking RFX6 into pancreatic islets, a significant decrease in PDX1 expression at the PF stage was observed, although this did not affect PPs co-expressing PDX1 and NKX6.1. …"
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97
A kinder and gentler workplace
منشور في 2013"…This article sheds light on the correlation that strongly exists between organizational culture and practices, employees' retention, and the bottom line.…"
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98
An adapted TPB approach to consumers’ acceptance of service-delivery drones
منشور في 2016"…Theorising related to this debate led to self-service technologies, which were implemented to both reduce costs and increase productivity by turning customers into co-producers of services or merely to keep up with technological developments. …"
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99
Local arterial vasoconstriction induced by octreotide in patients with cirrhosis
منشور في 2000"…Percent change in flow (%triangle up) was obtained by comparing the flow during drug administration to that during the preceding saline infusion. Saline infusion did not alter FBF, but octreotide infusion resulted in a 34% +/- 7.7 (P <.005) reduction in FBF in the infused arm. …"
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100
Rescue cerclage
منشور في 2006"…Advanced dilation of 3 cm and/or prolapsed membranes (n = 18) did not decrease the likelihood of reaching 28 weeks. …"
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article