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381
Human recombinant arginase I(Co)-PEG5000 [HuArgI(Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human acute myeloid leukemia cells
منشور في 2013"…In this study, we target arginine auxotrophy of AML cell lines using human arginase I cobalt-PEG5000. HuArgI(Co)-PEG5000 was cytotoxic to all AML cell lines tested. …"
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article -
382
Evaluation of transportation network reliability during unexpected events with multiple uncertainties
منشور في 2016"…On the supply side, in addition to link capacity, environment parameters of roads, which indirectly influence parameters of link travel time, are degraded after disasters. …"
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article -
383
The mechanisms of resistance of anthrax lethal toxin (LeTx)-induced cytotoxicity in AML cells. (c2018)
منشور في 2018"…Our results indicate that vertical inhibition by SCH772984 rendered the resistant cell lines sensitive to the inhibition of the MAPK-pathway and showed an increased cytotoxic effect once used in combination with anthrax lethal toxin compared to the use of anthrax lethal toxin alone.…"
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masterThesis -
384
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385
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386
Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018)
منشور في 2018"…Cytotoxicity of [HuArgI (Co)-PEG5000] was tested on two GBM cell lines, namely A172 and U251. Both cell lines showed increased sensitivity at longer incubation periods of [HuArgI (Co)-PEG5000] treatment with IC50 values in the pM range, a result attributable to the arginine auxotrophy expressed in those two cell lines. …"
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masterThesis -
387
Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications
منشور في 2019"…<i>CCL5</i> variants (<b>rs2107538</b> and <b>rs2280789</b>) were linked to CCL5 serum and mRNA levels. In the TCGA TNBC/Basal-like cohort the <b><i>MAP3K21</i></b><b> </b><b>rs1294255-G</b> allele was associated with a decreased OVS. …"
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388
Nanophthalmos and hemiretinal vein occlusion
منشور في 2015"…Many risk factors have been linked to retinal vein occlusions (RVOs) whether central or branch retinal vein occlusion. …"
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article -
389
Sulforaphane Delays Fibroblast Senescence by Curbing Cellular Glucose Uptake, Increased Glycolysis, and Oxidative Damage
منشور في 2018"…SFN delayed senescence by decreasing glucose metabolism on the approach to senescence, exhibiting a caloric restriction mimetic-like activity and thereby decreased oxidative damage to cell protein and DNA. …"
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390
Unraveling the impaired incretin effect in obesity and type 2 diabetes: Key role of hyperglycemia-induced unscheduled glycolysis and glycolytic overload
منشور في 2024"…Incretin effect impairment is characterized by decreased secretion of incretins from enteroendocrine cells and incretin resistance of pancreatic β-cells. …"
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391
Effects of Different Processing Methods on the Antibiotic Enrofloxacin Residues Occurrence in Middle Eastern Dairy Products
منشور في 2020"…There is a well-reported link between using antibiotics in farming and developing antibiotic resistance, which leads to subsequent human antibiotic treatment failure. …"
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masterThesis -
392
Serum 25-hydroxyvitamin D concentrations are inversely associated with body adiposity measurements but the association with bone mass is non-linear in postmenopausal women
منشور في 2021"…Vitamin D deficiency has been linked to increased adiposity and decreased bone density. …"
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article -
393
Fraud
منشور في 2017"…Because of the recent collapse of several major companies, investors' confidence in audited financial statements has decreased significantly. Fraud has been a major topic among many scholars and stakeholders due to its importance and impact on financial statements and economies at large. …"
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article -
394
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395
Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans
منشور في 2024"…In addition to cell lines, we assessed the impact of BTZ in an in vivo setting using Caenorhabditis elegans (C. elegans). …"
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396
A Power Ripple Compensator for DC Nanogrids via a Solid-State Converter
منشور في 2020"…This SSC is often considered as the main DC nanogrid energy control unit that is linking the nanogrid with the main utility AC grid and managing the nanogrid elements. …"
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397
Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres
منشور في 2024"…Cytotoxicity assays on human cell lines showed no toxicity towards cells at concentrations of up to 100 µg ml−1 but exhibited increased toxicity at concentrations exceeding 1000 µg ml−1. …"
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article -
398
Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
منشور في 2024"…Additionally, the distribution of livebirths across the globe is shifting, with a greater proportion occurring in the lowest-income countries. …"
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article -
399
The Anti-Proliferative and Pro-apoptotic Effect of Topotecan in Combination With Thymoquinone in Acute Myelogenous Leukemia
منشور في 2014"…Topotecan (a novel topoisomerase I inhibitor and a water-soluble camptothecin analog) is active against numerous human tumor cell lines, and has shown promising antineoplastic activity in solid tumors and acute leukemia. …"
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article -
400
Orofacial Clefts
منشور في 2021"…The striking difference in behavior was related to cell migration, whereby the patient-derived cells showed decreased motility, increased adhesion, and a general loss of polarity compared to the healthy cells. …"
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masterThesis