Wild carrot oil extract is selectively cytotoxic to human acute myeloid leukemia cells by Tawil, Mirna

“…In this study, we used Daucus carota oil extract (DCOE) to target acute myeloid leukemia (AML) cells. All the AML cell lines tested were sensitive to the extract while peripheral mononuclear cells were not. …”
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Artificial Intelligence in Predicting Cardiac Arrest: Scoping Review by Asma Alamgir (18288895)

“…Artificial intelligence (AI) technologies and big data have been increasingly used to enhance the ability to predict and prepare for the patients at risk.…”

Loss of the TRPM4 channel in humans causes immune dysregulation with defective monocyte migration by Fang Yu (156838)

“…Inhibition of TRPM4 in <u>T cells</u> and the THP-1 monocyte cell line reduces migration. More importantly, primary <u>T cells</u> and <u>monocytes</u> from TRPM4 patients migrate poorly. …”

Effectiveness of Intravenous Iron Therapy in the Management of Severe Iron Deficiency Anemia: A Retrospective Study by Obaidullah Zafar (17910572)

“…These findings highlight the need for individualized IV iron therapy as a first-line treatment in young healthy patients to improve outcomes and optimize healthcare resources.…”

Editorial: Dynamic Biomarkers of Response to Anti-Immune Checkpoint Inhibitors in Cancer by Said Dermime (79420)

“…<p dir="ltr">Immune checkpoint blockade (ICB) has been approved as first- or second-line therapy options in a broadening range of metastatic cancer and is increasingly explored in the treatment of early stage tumors. …”

Application of Fe₃O₄ magnetite nanoparticles grafted in silica (SiO₂) for oil recovery from oil in water emulsions by Wamda Faisal Elmobarak (17058024)

“…Demulsification process best fits the combined Langmuir-Freundlich (L-F) isotherm with highest adsorption capacity (Q_max) of 186.0 ± 5 mg_oil/g_MD compared to 86.0 ± 5 mg_oil/g_MD for Fe₃O₄, which is 1.1 folds greater than Q_max reported in the literature for other demulsifiers.…”

Masked phenomenon: renal and cardiovascular complications; review and updates by Elmukhtar Habas (14777677)

“…The masked phenomenon (MP) (MHTN and MUHTN) increases susceptibility to end-organ damage (a two-fold greater risk for cardiovascular events and kidney dysfunction). …”

Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients by Esraa K. Al-Amleh (16023071)

“…With regards to the treatment effect on hematological parameters, notably in CML patients in later stages, the combination therapy (HU + IM) raised lymphocyte count, indicating a greater response to the treatment. When compared to single medicines, the combination treatment reduced the proportion of neutrophils to normal reference ranges. …”

Characterization of the Potency and Mechanism of Action of a Novel Dual-Selective Intermolecularly Complemented Version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Breas... by Basala, Sobhiya

“…Results show that UACC-2087 cell line expresses the three proteases and upon treatment, the levels of expression were not consistent. …”
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Joint Adaptive Modulation and Channel Coding for Wireless Multimedia Communications by Zrae, Rimas Adnan

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Effectiveness and specificity of a classroom-based group intervention in children and adolescents exposed to war in Lebanon by Dimassi, Hani

“…These findings have significant policy and public health implications, given current practices of delivering universal interventions immediately post-war.…”
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A positive change in energy balance modulates TrkB expression in the hypothalamus and nodose ganglia of rats by Zeeni, Nadine

“…Adult male Wistar rats were given one of three diets for 6 weeks: high-carbohydrate, high-fat or high-fat pair-fed diets. …”
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Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells by Castellino, R.C.

“…Pre-treatment with sunitinib for 1 h also resulted in detachment and decreased viability of D556, but not Daoy, cells and only after 48 h following treatment. …”
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Role of Edge Groups in Defining the Stability of Aromatic Molecules Under Electron Irradiation by Y. Tong (18394389)

“…Qualitative description of the experimental results is given through bond distance-dependent total energy calculations and structural and electronic structure analysis within density functional theory. …”

Understanding the phenomenon of saltwater intrusion sourced from desalination plants at coastal aquifers by Farhat Abbas (5480)

“…Column Peclet numbers from the two analyses were identical for potassium ions but those for bromide ions were c. 60% greater from the two-region model than from the convective–diffusion equation. …”

Comparative study of the parameters affecting the performance of microchannels' heat exchangers: Latest advances review by Muhammad Asim (2235472)

“…Apart from this, investigating the inlet/outlet arrangement through finite volume method for D‐, I‐, N‐, S‐, U‐, and V‐type arrangements, it is evident that the V‐type sink has overall greater performance. In terms of gravity, it is observed that it has no effect on the performance of microchannel heat exchangers. …”

Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants by Bin, Zhou

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Annona cherimola Seed Extract Activates Extrinsic and Intrinsic Apoptotic Pathways in Leukemic Cells by Haykal, Tony

“…Treatment with an A. cherimola seed ethanolic extract promotes a dose- and time-dependent inhibition of the proliferation of various AML cell lines, but not MSCs. Positive Annexin V staining, as well as DNA fragmentation, confirm an increase in apoptotic cell death by upregulating the expression of pro-apoptotic proteins which control both intrinsic and extrinsic pathways of apoptosis. …”
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Annona cherimola Seed Extract Activates Extrinsic and Intrinsic Apoptotic Pathways in Leukemic Cells By Peter Nasr A thesis by Nasr, Peter

“…Treatment with an A. cherimola seed ethanolic extract promotes a dose- and time-dependent inhibition of the proliferation of various AML cell lines, but not MSCs. Positive Annexin V staining, as well as DNA fragmentation, confirm an increase in apoptotic cell death by upregulating the expression of pro-apoptotic proteins which control both intrinsic and extrinsic pathways of apoptosis. …”
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The antioxidant and anticancer effects of Wild Carrot oil extract by Shebaby, Wassim Nasri

“…The effect of DCOE on the cell lines exhibited time and dose-dependent responses. …”
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