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541
The Anti-Proliferative and Pro-apoptotic Effect of Topotecan in Combination With Thymoquinone in Acute Myelogenous Leukemia
منشور في 2014"…Topotecan (a novel topoisomerase I inhibitor and a water-soluble camptothecin analog) is active against numerous human tumor cell lines, and has shown promising antineoplastic activity in solid tumors and acute leukemia. …"
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article -
542
Phospho-MEK1/2 and uPAR Expression Determine Sensitivity of AML Blasts to a Urokinase-Activated Anthrax Lethal Toxin (PrAgU2/LF) 1
منشور في 2015"…PrAgU2/LF was cytotoxic to five out of nine AML cell lines. Cytotoxicity of PrAgU2/LF appeared to be nonapoptotic and was associated with MAPK activation and urokinase activity because all the PrAgU2/LF-sensitive cell lines showed both uPAR expression and high levels of MEK1/2 phosphorylation. …"
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article -
543
Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia
منشور في 2019"…Curcumin induces apoptosis in B-Pre-ALL cell lines via activation of caspase-8 and truncation of BID. …"
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544
Water-pipe smoking promotes epithelial–mesenchymal transition and invasion of human breast cancer cells via ERK1/ERK2 pathways
منشور في 2018"…Two breast cancer cell lines, MCF7 and BT20, were used in this investigation. …"
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545
Treatment with decitabine induces the expression of stemness markers, PD-L1 and NY-ESO-1 in colorectal cancer: potential for combined chemoimmunotherapy
منشور في 2023"…</p><h2>Methods</h2><p dir="ltr">We compared the effect of DAC in primary 1076 Col and metastatic 1872 Col cell lines isolated and generated from patients’ tumor tissues. …"
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546
The Candida albicans Hwp2 is necessary for proper adhesion, biofilm formation and oxidative stress tolerance
منشور في 2011"…It appears that Hwp2 is necessary for proper oxidative stress tolerance, adhesion and biofilm formation as an hwp2 null is more susceptible to increasing doses of hydrogen peroxide, unable to adhere efficiently to epithelial and endothelial cell lines and unable to form wild type biofilm levels.…"
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article -
547
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548
Human recombinant arginase I (Co)-PEG5000 [HuArgI (Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human glioblastoma cells
منشور في 2015"…We tested and characterized the activity of HuArgI (Co)-PEG5000 on a panel of 9 GBM cell lines and on human fetal glial cells (SVG-p12). HuArgI (Co)-PEG5000 was cytotoxic to all GBM cells tested. …"
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article -
549
INTEGRATING TRADITIONAL AND UNCONVENTIONAL CSR THEORIES AND MODELS – A THEORETICAL
منشور في 2020"…The surge in financial scandals, widening gaps in social inequality, increasing political and financial muscle by MNC’s, global uncertainties as well as environmental degradation has put the spotlight on firms to strengthen their involvement and be sensitive to socially responsible activities. …"
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550
Daucus carota pentane/diethyl ether fraction inhibits motility and reduces invasion of cancer cells
منشور في 2015"…Upon treatment, a pronounced decrease in cancer cell motility was observed in the 4 cell lines. The treatment also led to a decrease in cancer cell invasion and an increased cell adhesion. …"
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article -
551
The impact of political alliances on voter prejudice in post conflict countries
منشور في 2008"…Scholars of conflict resolution have studied ways to reduce prejudice in society for years, believing that prejudice leads to or increases the likelihood of conflict. The primary focus has been on schools, universities and communities. …"
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masterThesis -
552
Composite hydrogels from carrageenan-cl-carboxymethyl chitosan–PVA incorporated ZiF-8 as dressing material for wound healing applications
منشور في 2025"…The biocompatibility of the composite hydrogels has been evaluated using fibroblast cell lines (<i>3T3</i>) after different time intervals (24–72 h), and it was found that increasing ZiF-8 caused the mature and spread cell morphology with increasing cell viability and proliferation under controlled in vitro conditions. …"
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553
Breast cancer cells and bone marrow mesenchymal stromal cells
منشور في 2017"…While co-culture assays with SaOS-2 increased the expression of osteoblastic markers in MCF-7 cells, SaOS-2 cell conditioned medium increased the expression of RANKL, PTHrP, VEGF and NOGGIN in MCF-7 cells. …"
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article -
554
Occupational exposure assessment for power frequencyelectromagnetic fields
منشور في 1997"…The intensities of electromagnetic fields have been measured under power transmission and distribution lines, at substations and industrial plants and near various electric devices including domestic electrical equipment. …"
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article -
555
Assessing Struvite Formation Potential at Wastewater Treatment Plants
منشور في 2012"…Wastewater treatment plants, especially those employing secondary treatment and anaerobic sludge digestion, have historically encountered phosphate precipitates, one of the commonest being struvite, that foul and encrust the sludge return lines, and the associated pumps and valves. This growth of ‘uncontrolled’ struvite increases pumping and maintenance cost, as well as reduces the overall capacity of the plant piping system in terms of lost hydraulic capacity and lowered biological treatment capacity. …"
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556
Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function
منشور في 2017"…</p><h3>Results</h3><p dir="ltr">Assessment of primary cells and MEC lines confirmed expression of MMP-8 in normal MEC and its loss in DCIS-MEC. …"
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557
Regulative Loop between β-catenin and Protein Tyrosine Receptor Type γ in Chronic Myeloid Leukemia
منشور في 2020"…Furthermore, we demonstrated that the increased expression of β-catenin in PTPRG-negative CML cell lines correlates with DNA (cytosine-5)-methyl transferase 1 (DNMT1) over-expression, which is responsible for PTPRG promoter hypermethylation, while its inhibition or down-regulation correlates with PTPRG re-expression. …"
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558
Targeting of lactate dehydrogenase C dysregulates the cell cycle and sensitizes breast cancer cells to DNA damage response targeted therapy
منشور في 2021"…Silencing LDHC in four breast cancer cell lines significantly increased the presence of giant cells, nuclear aberrations, DNA damage, and apoptosis. …"
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559
Investigating the Crucial Role of School Leaders in Nurturing Middle Leaders to Enhance their Performance
منشور في 2023"…The study also emphasized the significance of open lines of communication between SLs and MLs. The study suggested potential techniques used by SLs like developing mentorship programs to offer advice and assistance, setting aside time for ML development, and fostering a culture of collaboration and shared leadership. …"
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560
Migrant workers and class structure in Lebanon
منشور في 2014"…Whilst a few scholars have examined the situation of domestic workers, the issue of migrant labor as a whole (its contribution to the labor market, the status and situation of different categories of workers, and their impact on the resilience of the Lebanese social structure), is largely ignored, whereas the high proportion of foreign workers in Lebanon results in an increasing fragmentation of the working class, and the embeddedness of the Lebanese class structure in globalization. …"
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