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501
A potential therapeutic agent for sickle cell anaemia
Published 2016“…</p><p>Patients with sickle cell anaemia produce 10 to 30 times more of a natural by-product of oxygen metabolism called reactive oxygen species (ROS) than healthy patients. …”
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502
The protective role of lidocaine in surgeries involving trigeminal nerve manipulation: a meta-analysis of trigeminocardiac reflex prevention
Published 2025“…This leads to a rapid increase in parasympathetic activity, resulting in a decrease in heart rate (HR) and blood pressure, which can potentially lead to bradycardia, and cardiac arrest, with a prevalence of 14.5% during neurointerventional procedures (8). …”
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503
A new perspective on cardiovascular drift during prolonged exercise
Published 2021“…<p dir="ltr">Prolonged exercise induces cardiovascular drift, which is characterized by decreasing mean arterial pressure (MAP), stroke volume and heart rate increase. …”
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504
COVID-19 biomarkers for severity mapped to polycystic ovary syndrome
Published 2020“…These protein panels target biological processes involved in vessel damage, platelet degranulation, the coagulation cascade and the acute phase response [1], with greater protein changes dependent on the COVID-19 severity. …”
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505
Chronic reduction of store operated Ca<sup>2+</sup> entry is viable therapeutically but is associated with cardiovascular complications
Published 2022“…The hypertension is not due to increased vascular smooth muscle contractility or vascular remodelling.…”
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506
A 5-year trend in the use of sodium-glucose co-transporter 2 inhibitors and other oral antidiabetic drugs in a Middle Eastern country
Published 2022“…The trend among SGLT2is suggests greater preference for empagliflozin over dapagliflozin.…”
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507
The Effectiveness of Mobile Phone Messaging–Based Interventions to Promote Physical Activity in Type 2 Diabetes Mellitus: Systematic Review and Meta-analysis
Published 2022“…<h3>Background</h3><p dir="ltr">The prevalence of type 2 diabetes mellitus (T2DM) is increasing worldwide. Physical activity (PA) is an important aspect of self-care and first line management for T2DM. …”
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508
An efficient claim management assurance system using EPC contract based on improved monarch butterfly optimization models
Published 2024“…Conventional construction models typically optimize only a single objective, such as time, cost, or delay, which may not effectively enhance overall performance. …”
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509
The July war and its effects on Lebanon’s power-sharing
Published 2007“…On a broader scale, this article helps shed light on the dilemma of power-sharing systems on stormy seas when external conflicts overlap with internal conflict lines.…”
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510
Recovery of business intelligence systems
Published 2018“…Reducing the execution time of recovery is the key target of our algorithm. …”
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511
Effectiveness of communication processes in Agile Project Management Approach in the UAE Utility Sector
Published 2023“…Team members should have a voice in the agile project management process, maintain open lines of communication with stakeholders, and discuss problems in a timely manner to increase tolerance and acceptance.…”
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512
Wild carrot oil extract is selectively cytotoxic to human acute myeloid leukemia cells
Published 2015“…In this study, we used Daucus carota oil extract (DCOE) to target acute myeloid leukemia (AML) cells. All the AML cell lines tested were sensitive to the extract while peripheral mononuclear cells were not. …”
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513
Artificial Intelligence in Predicting Cardiac Arrest: Scoping Review
Published 2021“…Artificial intelligence (AI) technologies and big data have been increasingly used to enhance the ability to predict and prepare for the patients at risk.…”
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514
Loss of the TRPM4 channel in humans causes immune dysregulation with defective monocyte migration
Published 2024“…Inhibition of TRPM4 in <u>T cells</u> and the THP-1 monocyte cell line reduces migration. More importantly, primary <u>T cells</u> and <u>monocytes</u> from TRPM4 patients migrate poorly. …”
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515
Effectiveness of Intravenous Iron Therapy in the Management of Severe Iron Deficiency Anemia: A Retrospective Study
Published 2025“…These findings highlight the need for individualized IV iron therapy as a first-line treatment in young healthy patients to improve outcomes and optimize healthcare resources.…”
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516
Editorial: Dynamic Biomarkers of Response to Anti-Immune Checkpoint Inhibitors in Cancer
Published 2021“…<p dir="ltr">Immune checkpoint blockade (ICB) has been approved as first- or second-line therapy options in a broadening range of metastatic cancer and is increasingly explored in the treatment of early stage tumors. …”
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517
Using primary healthcare facilities and patients’ expectations about triage system: Patients’ perspective from multisite Jordanian hospitals
Published 2024“…<h3>Background</h3><p dir="ltr"> Using primary healthcare facilities can decrease the tension and workload in emergency departments (EDs). …”
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Diabetic Sensorimotor Polyneuropathy Severity Classification Using Adaptive Neuro Fuzzy Inference System
Published 2021“…Early detection and intelligent classification tools for DSPN can allow correct diagnosis and treatment of painful diabetic neuropathy as well as a timely intervention to prevent foot ulceration, amputation, and other diabetic complications. …”
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Masked phenomenon: renal and cardiovascular complications; review and updates
Published 2024“…The masked phenomenon (MP) (MHTN and MUHTN) increases susceptibility to end-organ damage (a two-fold greater risk for cardiovascular events and kidney dysfunction). …”
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Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients
Published 2022“…With regards to the treatment effect on hematological parameters, notably in CML patients in later stages, the combination therapy (HU + IM) raised lymphocyte count, indicating a greater response to the treatment. When compared to single medicines, the combination treatment reduced the proportion of neutrophils to normal reference ranges. …”