Annona cherimola Seed Extract Activates Extrinsic and Intrinsic Apoptotic Pathways in Leukemic Cells By Peter Nasr A thesis by Nasr, Peter

“…Treatment with an A. cherimola seed ethanolic extract promotes a dose- and time-dependent inhibition of the proliferation of various AML cell lines, but not MSCs. Positive Annexin V staining, as well as DNA fragmentation, confirm an increase in apoptotic cell death by upregulating the expression of pro-apoptotic proteins which control both intrinsic and extrinsic pathways of apoptosis. …”
Get full text
Get full text
Get full text

The chemical analysis of Lebanese olive oil and the influence of oil enriched diet on Plasma Lipid profile in rats. (c2002) by Zarikian, Karen Awadis

“…In order to observe difference in lipid profile, well designed dietary experiments in humans is needed, because the squalene metabolism in rats is different than in humans.…”
Get full text
Get full text

Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis by Maria K. Smatti (4675852)

“…Indeed, further studies are needed to validate these findings as well as to identify new genetic determinants linked to SARS-CoV-2</p><h2>Other Information</h2><p dir="ltr">Published in: Frontiers in Genetics<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3389/fgene.2020.578523" target="_blank">https://dx.doi.org/10.3389/fgene.2020.578523</a></p>…”

Impact of birth weight to placental weight ratio and other perinatal risk factors on left ventricular dimensions in newborns: a prospective cohort analysis by Ashraf Gad (17040114)

“…PW correlated with IVSs (p=0.019), while the longest placental diameter was linked to a decrease in LV internal dimension during diastole (LVIDd) (estimate=−0.07, p=0.039), LV mass (estimate=−0.11, p=0.024), and LV mass/volume (estimate=−0.55, p=0.005).…”

The antioxidant and anticancer effects of Wild Carrot oil extract by Shebaby, Wassim Nasri

“…The effect of DCOE on the cell lines exhibited time and dose-dependent responses. …”
Get full text
Get full text
Get full text

Minimization of the amplitude of the entire span of beams using mass dampers by Issa, Jimmy S.

“…The optimal placement of the mass damper is chosen such that the maximum of these lines is minimized. Then, the optimal damping constant is obtained analytically from an average of two damping ratios corresponding each to one of the peaks of the amplitude of the entire beam span to coincide with one of the two equally leveled maxima of the fixed-lines. …”
Get full text
Get full text
Get full text
Get full text

Global, regional, and national burden of household air pollution, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 by Fiona B, Bennitt

“…The rate of global, HAP-attributable DALYs in 2021 was 1500·3 (95% UI 1028·4–2195·6) age-standardised DALYs per 100 000 population, a decline of 63·8% since 1990, when HAP-attributable DALYs comprised 4147·7 (3101·4–5104·6) age-standardised DALYs per 100 000 population. …”
Get full text
Get full text
Get full text

Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990–2021, for 204 countries and territories: a systematic analy... by Hmwe Hmwe, Kyu

“…The most pronounced decline was in children younger than 5 years, with a 79·2% (72·4–84·6) decrease in diarrhoeal deaths. Global YLLs also decreased substantially, from 186 million (147–221) in 1990 to 51·4 million (39·9–65·9) in 2021. …”
Get full text
Get full text
Get full text

The effect of daucus carota pentane-diethylether fraction on cancer cells motility and metastasis. (c2013) by Zgheib, Perla Z.

“…Upon treatment, a pronounced decrease in cancer cell motility was observed in the four cell lines used. The treatment also led to a decrease in cancer cell invasion and an increased cell adhesion. …”
Get full text
Get full text

Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma by Peter Kubatka (11008854)

“…(sumac) using animal models (rat and mouse), and cell lines of breast carcinoma. R. coriaria (as a powder) was administered through the diet at two concentrations (low dose: 0.1% (w/w) and high dose: 1 % (w/w)) for the duration of the experiment in a syngeneic 4T1 mouse and chemically-induced rat mammary carcinoma models. …”

Achieving a systematic service integration program for children with challenging behaviors in school setting in Lebanon. (c2015) by Mahmoud, Hadeel

“…However, there are limitations of this study, which need to be taken in consideration for further studies.…”
Get full text
Get full text

Fraud by Jizi, Mohammad

“…Because of the recent collapse of several major companies, investors' confidence in audited financial statements has decreased significantly. Fraud has been a major topic among many scholars and stakeholders due to its importance and impact on financial statements and economies at large. …”
Get full text
Get full text
Get full text
Get full text

Curcumin encapsulated colloidal amphiphilic block co-polymeric nanocapsules by Bechnak, Linda

“…The cytotoxicity of curcumin and colloidal nanocapsules was assessed using human derived immortalized cell lines (A549 and A375 cells) in the presence and absence of light irradiation. …”
Get full text
Get full text
Get full text
Get full text

Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis by Meritxell Espino‐Guarch (22565774)

“…Further, chronic Gln accumulation and decreased proteolysis were found to induce the early onset of an age‐related muscle phenotype.…”

Global, regional, and national stillbirths at 20 weeks' gestation or longer in 204 countries and territories, 1990–2021: findings from the Global Burden of Disease Study 2021 by Comfort, Haley

“…Findings: In 2021, the global stillbirth rate was 23·0 (95% uncertainty interval [UI] 19·7–27·2) per 1000 births (stillbirths plus livebirths) at 20 weeks' gestation or longer, compared to 16·1 (13·9–19·0) per 1000 births at 28 weeks' gestation or longer. …”
Get full text
Get full text
Get full text

Flavonoids Alleviate Peripheral Neuropathy Induced by Anticancer Drugs by Manaal Siddiqui (18891637)

“…Specifically, precise pharmacological mechanisms and side effects need to be elucidated in human models before clinical benefits can be achieved.…”

Investigating the Quality Combined Effect of Root Cause Analysis (RCA) in Quality Management in Manufacturing Firms by ALBLOOSHI, ROUDHA KHALID ABDULLA

“…Such products need to be manufactured more often if companies want to survive in the Middle East as consumers will not settle for anything less. …”
Get full text

Comparative Effect of Sodium Butyrate and Sodium Propionate on Ovarian Cancer Migration, Invasion, and Epithelial-To-Mesenchymal Transition by Sleem, Reem

“…Methodology: The two ovarian cancer cell lines, SKOV-3 and PA-1, were treated with NaB and NaP for 24h. …”
Get full text
Get full text
Get full text

Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells by Al Sayyed, Fatima

“…In this study, we investigate the efficacy of two small molecules Ruxolitinib, a JAK/STAT inhibitor, and CHIR-99021, a GSK-3 inhibitor, in targeting pediatric neuroblastoma stem cells by testing them on human MYC-N amplified, IMR-32, and non-MYC-N amplified, SK-N-SH, cell lines. Treating neuroblastoma cells with Ruxolitinib and CHIR-99021 resulted in significant reduction in cellular proliferation, viability, apoptosis and tumorsphere formation capacity in both IMR-32 and SK-N-SH cell lines. …”
Get full text
Get full text
Get full text

Anticancer activity of Neosetophomone B by targeting AKT/SKP2/MTH1 axis in leukemic cells by Shilpa Kuttikrishnan (3520079)

“…<p>Neosetophomone B (NSP–B), a meroterpenoid fungal secondary metabolite, was investigated for its anticancer potential in leukemic cell lines (K562 and U937). NSP-B treatment of leukemic cells suppressed cell viability by triggering apoptotic cell death. …”