Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function by Muge Sarper (3855454)

“…</p><h3>Results</h3><p dir="ltr">Assessment of primary cells and MEC lines confirmed expression of MMP-8 in normal MEC and its loss in DCIS-MEC. …”

Regulative Loop between β-catenin and Protein Tyrosine Receptor Type γ in Chronic Myeloid Leukemia by Luisa Tomasello (702932)

“…Furthermore, we demonstrated that the increased expression of β-catenin in PTPRG-negative CML cell lines correlates with DNA (cytosine-5)-methyl transferase 1 (DNMT1) over-expression, which is responsible for PTPRG promoter hypermethylation, while its inhibition or down-regulation correlates with PTPRG re-expression. …”

Targeting of lactate dehydrogenase C dysregulates the cell cycle and sensitizes breast cancer cells to DNA damage response targeted therapy by Adviti Naik (673163)

“…Silencing LDHC in four breast cancer cell lines significantly increased the presence of giant cells, nuclear aberrations, DNA damage, and apoptosis. …”

Investigating the Crucial Role of School Leaders in Nurturing Middle Leaders to Enhance their Performance by ALLABABIDI, FARAH

“…The study also emphasized the significance of open lines of communication between SLs and MLs. The study suggested potential techniques used by SLs like developing mentorship programs to offer advice and assistance, setting aside time for ML development, and fostering a culture of collaboration and shared leadership. …”
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Migrant workers and class structure in Lebanon by Tabar, Paul

“…Whilst a few scholars have examined the situation of domestic workers, the issue of migrant labor as a whole (its contribution to the labor market, the status and situation of different categories of workers, and their impact on the resilience of the Lebanese social structure), is largely ignored, whereas the high proportion of foreign workers in Lebanon results in an increasing fragmentation of the working class, and the embeddedness of the Lebanese class structure in globalization. …”
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Unmasking Hidden Gluten: Evaluating the Compliance of Gluten-Free Products and Consumer Exposure in Lebanon by Assi, Ranim Mohammed

“…Strengthened regulatory surveillance, dedicated production lines for high-risk categories, and targeted consumer education must be enforced to safeguard medically vulnerable populations and uphold ethical standards.…”
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The Candida albicans HWP2 protein is necessary for proper adhesion, biofilm formation and can complement a saccharomyces cerevisiae MUC1 null strain. (c2010) by Younes, Samer

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The US Public’s Views of Paradiplomacy, 1988–2024 by Paul Musgrave (12982827)

“…I report on a 2024 survey of Americans’ paradiplomacy views that updates a 1988 poll conducted by the federal Advisory Commission on Intergovernmental Relations. I find increased support for paradiplomatic activities, but I also find that the degree of support varies by activities’ objective, demographic characteristics, and partisan identity. …”

Characterizing the Effect of Arginine Deprivation on Autophagic Response in Breast Cancer cells by Haidar, Fatemah

“…Residual ASS1 tumor expression corelated with increased metastasis and decreased survival in patient luminal A, Her2+ and triple-negative breast cancer. …”
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Early results of total hip arthroplasty using dual-mobility cup in patients with osteonecrosis of the femoral head by Assi, Chahine

“…The majority of these patients are young with high functional demand, and show an increased risk of dislocation following surgery than patients with osteoarthritis. …”
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Humanizing AI in medical training: ethical framework for responsible design by Mohammed Tahri Sqalli (18420840)

“…<p dir="ltr">The increasing use of artificial intelligence (AI) in healthcare has brought about numerous ethical considerations that push for reflection. …”

Impact of Charging Electric Vehicles under Different State of Charge Levels and Extreme Conditions by Claude Ziad El-Bayeh (17542284)

“…<p dir="ltr">High penetration levels of Plug-in Electric Vehicles (PEVs) could cause stress on the network and might violate the limits and constraints under extreme conditions, such as exceeding power and voltage limits on transformers and power lines. This paper defines extreme conditions as the state of a load or network that breaks the limits of the constraints in an optimization model. …”

Intelligent Rapidly-Exploring Random Tree Star Algorithm by Ahmed, Khidir Galal Eldin Khidir

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Crosstalk between aryl hydrocarbon receptor (AhR) and BCL-2 pathways suggests the use of AhR antagonist to maintain normal differentiation state of mammary epithelial cells during... by Abdullah, Al-Dhfyan

“…ResultsActivation of the AhR/CYP1A1 pathway in mice increased EpCAMHigh/CD49fLow CD61+ luminal progenitor-like cells in early tumor formation but not in advanced tumors. …”
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Comparative Effect of Sodium Butyrate and Sodium Propionate on Proliferation, Cell Cycle and Apoptosis in Ovarian Cancer Cells by Danaf, Daniella

“…This study aimed to investigate and compare the anti-tumor effects of NaB and NaP in two distinctive ovarian cancer cell lines, SKOV-3 and PA-1. The effect of NaB and NaP on proliferation was assessed in 2D and 3D through MTT assay, colony formation assay, and spheroid hanging drop method. …”
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Neosetophomone B induces apoptosis in multiple myeloma cells via targeting of AKT/SKP2 signaling pathway by Shilpa Kuttikrishnan (3520079)

“…Our study investigated NSP‐B's antitumor effects on MM cell lines (U266 and RPMI8226) and the involved molecular mechanisms. …”

Simulating blood vessel scaffolds by Nature Research (16552612)

“…According to their simulations, the amount of shear stress is highest at the endoluminal strut surface, where the stent comes into contact with the inner lining of the vessels, but very low at the areas where blood flows in and out of the device. …”

Evaluation of Estrone Liposomes using Microfluidics for Breast Cancer Therapy by Al Bostami, Rouba D.

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Electric Grid Resilience Enhancement During Natural Disasters: An Optimization-Based UAV Inspection and Dynamic Crew Dispatch Model by Serag, Yousef

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Selective induction of apoptosis in T-cell acute lymphoblastic leukemia by pristimerin through dual PI3K/AKT pathway inhibition and ROS generation by Shilpa Kuttikrishnan (3520079)

“…In this study, we demonstrate that Prist effectively inhibits the proliferation of T-ALL cell lines (Jurkat and Molt 4) by inducing G0/G1 cell cycle arrest and triggering intrinsic and extrinsic caspase-dependent apoptosis. …”