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441
Association between sources of sexuality education, sexual beliefs and behaviours in Lebanese young adults
منشور في 2020"…Sex and classes on reproductive health predicted a rise in SBI. The timing of classes, namely earlier introduction, and communication with family and religious figures predicted a decrease in SBI. …"
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442
A novel inhibitor of STAT3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T cells
منشور في 2008"…Experimental Design The antitumor activities and related mechanisms of WP1066 were investigated both in vitro on melanoma cell lines and in vivo on mice with subcutaneously syngeneic melanoma or with intracerebral melanoma tumors. …"
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443
A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T ce...
منشور في 2008"…Experimental Design: The antitumor activities and related mechanisms of WP1066 were investigated both in vitro on melanoma cell lines and in vivo on mice with subcutaneously syngeneic melanoma or with intracerebral melanoma tumors. …"
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444
Effect of StarD13 on colorectal cancer proliferation, motility and invasion
منشور في 2014"…Colon cancer is a cancer of the epithelial cells lining the colon. It is mainly divided into different stages according to the invasiveness and metastatic ability of the tumor. …"
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445
Clinical correlates of white-matter abnormalities on head magnetic resonance imaging
منشور في 2001"…Children with white-matter abnormalities and increased tone had a greater frequency of increased reflexes and tended to have more signal abnormalities than the other groups. …"
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446
Tuberculosis following programmed cell death receptor-1 (PD-1) inhibitor in a patient with non-small cell lung cancer. Case report and literature review
منشور في 2022"…Nonetheless, tuberculosis (TB) reactivation during their use is increasingly recognized and reported. Herein, we present a 58-year-old lady with advanced non-small cell lung cancer (NSCLC) ALK-negative, EGFR wild, and PD-L1 immune histochemistry (IHC) strongly positive in 95% of tumor cells, on ongoing treatment with Pembrolizumab as a first-line monotherapy. …"
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447
Dynamic Biomarkers of Response to Anti-Immune Checkpoint Inhibitors in Cancer
منشور في 2021"…To date, immune check-point inhibitors have been approved as first or second line therapy options in a broadening range of metastatic cancer and increasingly explored in the treatment of early stage tumors. …"
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448
PD-L1 Blockade by Atezolizumab Downregulates Signaling Pathways Associated with Tumor Growth, Metastasis, and Hypoxia in Human Triple Negative Breast Cancer
منشور في 2019"…In this study, we investigated the molecular mechanisms by which the human TNBC cell line MDA-MB-231, expressing PD-L1, responds to atezolizumab, using RNA-Seq. …"
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449
Prevalence and global trends of polypharmacy in patients with chronic kidney disease: A systematic review and meta-analysis
منشور في 2023"…In line with the therapeutic guidelines, managing CKD and its complications necessitates prescribing multiple medications, which predisposes patients to polypharmacy. …"
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450
Need for Affect, Problematic Social Media Use and the Mediating Role of Fear of Missing Out in European and Arab Samples
منشور في 2023"…<h3>Purpose </h3><p dir="ltr">The growing awareness and concern about the excessive use of social media have led to an increasing number of studies investigating the underlying factors contributing to this behavior. …"
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451
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452
The impact of cultural diversity on project management communication
منشور في 2022"…The results of the study are in line with some previous research, who said that when examined in terms of age, gender, and ethnicity, having a diverse workforce has a positive impact on the organization's performance. …"
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453
Effects of selenium in comparison to exendin-4 on the expression of GLP-1R, IRS-1 and preproinsulin in the pancreas of diabetic rats
منشور في 2016"…It binds and activates GLP-1R with greater potency than GLP-1 and is used in the treatment of diabetes mellitus. …"
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454
Trends in criminal convictions in Japan for vehicle collisions where one driver suffers from an epileptic seizure
منشور في 2015"…To reduce collisions to an even greater degree, this type of collision should be prevented. …"
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455
The synthetic cathinones MDPHP and MDPV: Comparison of the acute effects in mice, in silico ADMET profiles and clinical reports
منشور في 2024"…Our results substantiated that MDPHP and MDPV similarly affect sensorimotor and behavioural responses in mice, importantly increased locomotion and induced aggressive behaviour, and, at higher dosage, increased heart rate and blood pressure. …"
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456
SYSTEM DYNAMICS APPROACH FOR WHOLE LIFE CYCLE COST MODELLING OF RESIDENTIAL BUILDING PROJECTS IN UNITED ARAB EMIRATES
منشور في 2020"…This is achieved by applying adjusting risks on project's initial cost at the preconstruction stage with respect to cost and risk behaviours at each time step. Cost impact is following an increasing S-Curve behaviour during CAPEX time and risk impact is following a decreasing S-Curve behaviour during CAPEX lifetime. …"
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457
Vitamin D Association With Macrophage-Derived Cytokines in Polycystic Ovary Syndrome: An Enhanced Risk of COVID-19 Infection?
منشور في 2021"…Vitamin D deficiency was associated with decreased CD80 and IFN-γ in PCOS and IL-12 in both groups (p<0.05). …"
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458
Effects of COVID-19 on Autism Spectrum Disorder in Qatar
منشور في 2024"…Parents also reported decreased access to family and social support networks, as well as decreased quality of clinical and community support. …"
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459
Optoelectronic properties of highly porous silver oxide thin film
منشور في 2021"…The Ag<sub>2</sub>O phase of silver oxide appears after 300 s of oxidation under the same conditions, while the optical transparency of the thin film decreases as plasma etching time increases. The sheet resistance of the final film is influenced by the oxidation time and the plasma application periodicity.…"
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460
The Triple “S” Impact of COVID-19: Nationwide Evidence of the Impact of the Stress Associated With Restrictive Measures on Substance Use, Sleep, and Social Connectedness in Qatar...
منشور في 2023"…Of tobacco users in our sample, 36% reported increased tobacco use since the start of home confinement, while 41.6% of alcohol users reported decreased alcohol use. Concerning sleep, 46.1% reported an increase in average sleep duration per day (0.77 h mean increase, 95% CI: 0.66-0.88, P<0.001), and a third of participants reported poorer sleep quality. …"