Loss of the TRPM4 channel in humans causes immune dysregulation with defective monocyte migration حسب Fang Yu (156838)

"…Inhibition of TRPM4 in <u>T cells</u> and the THP-1 monocyte cell line reduces migration. More importantly, primary <u>T cells</u> and <u>monocytes</u> from TRPM4 patients migrate poorly. …"

Effectiveness of Intravenous Iron Therapy in the Management of Severe Iron Deficiency Anemia: A Retrospective Study حسب Obaidullah Zafar (17910572)

"…These findings highlight the need for individualized IV iron therapy as a first-line treatment in young healthy patients to improve outcomes and optimize healthcare resources.…"

Editorial: Dynamic Biomarkers of Response to Anti-Immune Checkpoint Inhibitors in Cancer حسب Said Dermime (79420)

"…<p dir="ltr">Immune checkpoint blockade (ICB) has been approved as first- or second-line therapy options in a broadening range of metastatic cancer and is increasingly explored in the treatment of early stage tumors. …"

Using primary healthcare facilities and patients’ expectations about triage system: Patients’ perspective from multisite Jordanian hospitals حسب Mohammad Minwer Alnaeem (19143733)

"…<h3>Background</h3><p dir="ltr"> Using primary healthcare facilities can decrease the tension and workload in emergency departments (EDs). …"

Diabetic Sensorimotor Polyneuropathy Severity Classification Using Adaptive Neuro Fuzzy Inference System حسب Fahmida Haque (16896489)

"…Early detection and intelligent classification tools for DSPN can allow correct diagnosis and treatment of painful diabetic neuropathy as well as a timely intervention to prevent foot ulceration, amputation, and other diabetic complications. …"

Evaluation of 3D Concrete Printing in the United Arab Emirates حسب Alchaar, Aktham S.

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Soil Characterization Utilizing GPR Technique حسب Al Kej, Fateh Tamam

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Masked phenomenon: renal and cardiovascular complications; review and updates حسب Elmukhtar Habas (14777677)

"…The masked phenomenon (MP) (MHTN and MUHTN) increases susceptibility to end-organ damage (a two-fold greater risk for cardiovascular events and kidney dysfunction). …"

Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients حسب Esraa K. Al-Amleh (16023071)

"…With regards to the treatment effect on hematological parameters, notably in CML patients in later stages, the combination therapy (HU + IM) raised lymphocyte count, indicating a greater response to the treatment. When compared to single medicines, the combination treatment reduced the proportion of neutrophils to normal reference ranges. …"

Evaluation of Workability and Structuration Rate of Locally Developed 3D Printing Concrete Using Conventional Methods حسب Ahmed, Sara

"…Therefore, the main objective of this research was to develop 3D printing mixes with different aggregate-to-binder (a/b) ratios (1.2, 1.5, and 1.8) and evaluate it in terms of its fresh printing properties, which include the workability, extrudability, setting time, open time, and buildability. The compressive strengths of cast and printed specimens were also tested to determine the effect of the layering process. …"
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Effects of Operating Conditions on Water Absorption Capacity of Superabsorbent Hydrogels حسب Abdelwahab, Noun

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Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burd... حسب Katherine R Paulson (8674293)

"…</p><p><br></p><h3>Findings</h3><p dir="ltr">Global U5MR decreased from 71·2 deaths per 1000 livebirths (95% uncertainty interval [UI] 68·3–74·0) in 2000 to 37·1 (33·2–41·7) in 2019 while global NMR correspondingly declined more slowly from 28·0 deaths per 1000 live births (26·8–29·5) in 2000 to 17·9 (16·3–19·8) in 2019. …"

An Experimental Investigation of the Effects of Dressing and Grinding Parameters on Sustainable Grinding of Inconel 738 Used for Automated Manufacturing حسب Mohammadjafar Hadad (17541345)

"…<p dir="ltr">The significant effect of the dressing process on the surface of the grinding wheel (GW) and the need to provide an optimal dressing condition are the requirements of reduction machining time and energy consumption in the sustainable grinding process. …"

PSA-activated proaerolysin as a prostate specific cancer therapy حسب Abi-Habib, Ralph

"…Activity toward proaerolysin was decreased 10-100 fold for each of the proteases tested except PSA, which showed a 4-fold increase in activity against the modified protein. …"
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The burden of prostate cancer in North Africa and Middle East, 1990–2019: Findings from the global burden of disease study حسب Mohsen Abbasi-Kangevari (9714440)

"…</p><h3>Results</h3><p dir="ltr">The age-standardized rates (95% UI) of PCa incidence, prevalence, and death in 2019 were 23.7 (18.5-27.9), 161.1 (126.6-187.6), and 11.7 (9.4-13.9) per 100,000 population. While PCa incidence and prevalence increased by 77% and 144% during 1990-2019, respectively, the death rate stagnated. …"

Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019 حسب Razieh, Hassannejad

"…FindingsIn contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. …"
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Characterization of the Potency and Mechanism of Action of a Novel Dual-Selective Intermolecularly Complemented Version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Breas... حسب Basala, Sobhiya

"…Results show that UACC-2087 cell line expresses the three proteases and upon treatment, the levels of expression were not consistent. …"
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Joint Adaptive Modulation and Channel Coding for Wireless Multimedia Communications حسب Zrae, Rimas Adnan

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Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery حسب Stephen L. Atkin (6684368)

"…<h3>Background: </h3><p dir="ltr">Early metabolic responses following bariatric surgery appear greater than expected given the initial weight loss and coincide with improvement in diabetes. …"

Understanding the phenomenon of saltwater intrusion sourced from desalination plants at coastal aquifers حسب Farhat Abbas (5480)

"…Column Peclet numbers from the two analyses were identical for potassium ions but those for bromide ions were c. 60% greater from the two-region model than from the convective–diffusion equation. …"