Neosetophomone B induces apoptosis in multiple myeloma cells via targeting of AKT/SKP2 signaling pathway حسب Shilpa Kuttikrishnan (3520079)

"…Our study investigated NSP‐B's antitumor effects on MM cell lines (U266 and RPMI8226) and the involved molecular mechanisms. …"

Dexamethasone Promotes a Stem-Like Phenotype in Human Melanoma Cells <i>via</i> Tryptophan 2,3 Dioxygenase حسب Marta Cecchi (21363581)

"…Moreover, dex stimulates spherogenesis of both cell lines, which is mediated by TDO, evident by its suppression with 680C91, a TDO inhibitor. …"

Evaluation of Estrone Liposomes using Microfluidics for Breast Cancer Therapy حسب Al Bostami, Rouba D.

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Electric Grid Resilience Enhancement During Natural Disasters: An Optimization-Based UAV Inspection and Dynamic Crew Dispatch Model حسب Serag, Yousef

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Effects of natural organic matter on aggregation kinetics of boron nanoparticles in monovalent and divalent electrolytes حسب Liu, Xuyang

"…However, the attachment efficiency kept increasing in the presence of CaCl2 and alginate with the increase in the electrolyte concentration and was greater than unity at >4 mM CaCl2. The destabilization was attributed to bridging of the nanoparticles by the alginate–Ca2+ system. …"
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Trends in criminal convictions in Japan for vehicle collisions where one driver suffers from an epileptic seizure حسب Mineko Baba (19774386)

"…<p dir="ltr">For the last fourteen years in Japan, casualties due to traffic collisions have decreased. There were 9,073 traffic fatalities in 2000 and 4,113 in 2014. …"

Optimum sizing of steam turbines for concentrated solar power plants حسب Poullikkas, Andreas

"…Finally, although the cost of electricity of a CSP plant with capacities greater than 1MWe is significantly reduced to less than 1US$/kWh, currently such technology can only become economically viable through supporting schemes.…"
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A framework for implementing Green Supply Chain Management: The Case of Petco Gulf حسب HASSAN, HUDA YOUSIF ALI AHMED

"…This will give any company a competitive edge and boost its sales by building up the company’s reputation amongst its stakeholders, especially the consumers. …"
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A control algorithm to increase the efficient operation of wind energy conversion systems under extreme wind conditions حسب Nyam Jargalsaikhan (17380429)

"…<p dir="ltr">This paper aims to increase the power production of gearless permanent magnet synchronous generator (PMSG) based wind energy conversion systems (WECS) in strong (greater than 25 m/s) wind speed regions. In general, most wind turbines cut off when wind speed is over the cut-out rate; as a result, the power generation of the wind farm decreases. …"

A novel inhibitor of STAT3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T cells حسب Abou-Ghazal, Mohamed K.

"…Results WP1066 achieved an IC50 of 1.6 μM, 2.3 μM, and 1.5 μM against melanoma cell line A375, B16 and B16EGFRvIII, respectively. WP1066 suppressed the phosphorylation of JAK2 and STAT3 (Tyr705) in these cells. …"
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A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T ce... حسب Abou-Ghazal, Mohamed

"…Experimental Design: The antitumor activities and related mechanisms of WP1066 were investigated both in vitro on melanoma cell lines and in vivo on mice with subcutaneously syngeneic melanoma or with intracerebral melanoma tumors. …"
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Tumor protease-activated fusion toxins حسب Abi-Habib, Ralph J.

"…In this study, we demonstrate that DTU2GMCSF is highly potent against AML cell lines in vitro and is not toxic to normal cells both in vitro and in vivo. …"
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Selective induction of apoptosis in T-cell acute lymphoblastic leukemia by pristimerin through dual PI3K/AKT pathway inhibition and ROS generation حسب Shilpa Kuttikrishnan (3520079)

"…Prist significantly increases reactive oxygen species (ROS) levels and depletes glutathione (GSH), leading to mitochondrial dysfunction and cytochrome c release. …"

Protein arginine methyltransferase 5 (PRMT5) activates WNT/β‐catenin signalling in breast cancer cells via epigenetic silencing of DKK1 and DKK3 حسب Harshita Shailesh (14779408)

"…<p></p><div> <p>Protein arginine methyltransferase 5 (PRMT5) activity is dysregulated in many aggressive cancers and its enhanced levels are associated with increased tumour growth and survival. However, the role of PRMT5 in breast cancer remains underexplored. …"

Inositol 1,4,5-Trisphosphate Receptors in Hypertension حسب Ali H. Eid (5461829)

"…This involves a phenotypic switch of VSMCs as well as an alteration of cytoplasmic Ca²⁺ signaling machinery, a phenomena tightly related to the aging process. Several lines of evidence implicate changes in expression/function levels of IP₃R isoforms in the development of hypertension, VSMC phenotypic switch, and vascular aging. …"

Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway حسب Kirti.S. Prabhu (17191231)

"…SNG treatment increased Bax/Bcl-2 ratio, which contributed to a leaky mitochondrial membrane leading to cytochrome c release accompanied by caspase activation. …"

Dietary protein level alters gentamicin-induced nephrotoxicity in rats حسب Zeeni, N.

"…Results showed that chronic gentamicin treatment leads to a decrease in food intake and flattening of the rhythms of food ingestion. …"
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Ultrasound‑triggered herceptin liposomes for breast cancer therapy حسب Elamir, Amal

"…Exposing the liposomes to low-frequency ultrasound (LFUS) triggered drug release which increased with the increase in power density. Trastuzumab conjugation resulted in enhancing the sensitivity of the liposomes to LFUS. …"
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Assessment of High-resolution Local Emissions and Land-use in Air Quality Forecasting at an Urban, Coastal, Desert Environment حسب Christos Fountoukis (4722963)

"…The model’s forecast accuracy was assessed against measurement data from five ground air quality monitoring stations in the greater metropolitan area of Doha over a one-month period. …"

The Effects of Online Formative and Summative Assessment on Test Anxiety and Performance: A Study Among First-Year Undergraduate Students at A Higher Education Institution in Abu D... حسب ALSUWAIDI, MUNA

"…The presented study was conducted to provide greater insight into the potential positive, neutral and/or negative effects of online formative and summative assessment on test anxiety and performance. …"
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