A potential therapeutic agent for sickle cell anaemia حسب Nature Research (16552612)

"…They also found increased levels of ROS that were associated with decreased levels of antioxidant enzymes and their co-factors.…"

Retinal imaging based glaucoma detection using modified pelican optimization based extreme learning machine حسب Debendra Muduli (20748758)

"…The effectiveness has been evaluated using two standard datasets called G1020 and ORIGA with the $$10 \times 5$$-fold stratified cross-validation technique to ensure reliable evaluation. …"

Application of Fe₃O₄ magnetite nanoparticles grafted in silica (SiO₂) for oil recovery from oil in water emulsions حسب Wamda Faisal Elmobarak (17058024)

"…Using an MD_dose as low as 10 mg/L attained a %_hdem in the range of 93% - 4.3% for O/W mixtures with C_oil < 2000 mg/L, which slightly decreased to ~90% for higher concentrations. The reported %R_oil(p-value <0.05) was >90 ± 0.1 for tests carried out with pH 7 and C_sur0.1 g/L and declined at higher pH and Csur to % 86.5 due to the increase in emulsion stability. …"

Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia حسب Shilpa Kuttikrishnan (3520079)

"…Curcumin induces apoptosis in B-Pre-ALL cell lines via activation of caspase-8 and truncation of BID. …"

Water-pipe smoking promotes epithelial–mesenchymal transition and invasion of human breast cancer cells via ERK1/ERK2 pathways حسب Khaled W. Sadek (14153196)

"…<p>With the increasing popularity of water-pipe smoking (WPS), it is critical to comprehend how WPS may affect women’s health. …"

Phospho-MEK1/2 and uPAR Expression Determine Sensitivity of AML Blasts to a Urokinase-Activated Anthrax Lethal Toxin (PrAgU2/LF) 1 حسب Nasser, Selim

"…PrAgU2/LF was cytotoxic to five out of nine AML cell lines. Cytotoxicity of PrAgU2/LF appeared to be nonapoptotic and was associated with MAPK activation and urokinase activity because all the PrAgU2/LF-sensitive cell lines showed both uPAR expression and high levels of MEK1/2 phosphorylation. …"
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Unsustainability in emergent systems حسب Haddad, Marc

"…In this paper we present a detailed case study of the passenger road transport system in the Greater Beirut Area (GBA) where we identify the root causes of the major problems facing the system today and over the long-term. …"
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Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways حسب Shehaby, Wassim N.

"…Flow cytometric analysis indicated that both fractions induced sub-G1 phase accumulation and increased apoptotic cell death. Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. …"
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Enhanced cellular uptake and photochemotherapeutic potential of a lipophilic strained Ru(II) polypyridyl complex حسب Mehanna, Stephanie

"…When compared to cisplatin, the photoproducts were more potent against all tested cell lines, implying that the complex acquired significant chemotherapeutic potential upon irradiation. …"
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Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance حسب Ajaz A. Bhat (12984701)

"…<p>Early-stage detection of leukemia is a critical determinant for successful treatment of the disease and can increase the survival rate of leukemia patients. The factors limiting the current screening approaches to leukemia include low sensitivity and specificity, high costs, and a low participation rate. …"

PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications حسب Pramod Darvin (153341)

"…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …"

Hydrophobic Ionic Liquids for Efficient Extraction of Oil from Produced Water حسب Liaqat, Shehzad

"…The extraction efficiency was found to increase with increasing cation alkyl chain length from C2 to C10. …"
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Using primary healthcare facilities and patients’ expectations about triage system: Patients’ perspective from multisite Jordanian hospitals حسب Mohammad Minwer Alnaeem (19143733)

"…<h3>Background</h3><p dir="ltr"> Using primary healthcare facilities can decrease the tension and workload in emergency departments (EDs). …"

Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres حسب Radha, Remya

"…Cytotoxicity assays on human cell lines showed no toxicity towards cells at concentrations of up to 100 µg ml−1 but exhibited increased toxicity at concentrations exceeding 1000 µg ml−1. …"
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Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans حسب Kirti S. Prabhu (4246144)

"…In addition to cell lines, we assessed the impact of BTZ in an in vivo setting using Caenorhabditis elegans (C. elegans). …"

Urtica dioica extract and its impact on blood lipids, glycemia & inflammation in the rat model. (c2005) حسب Baroudy, Karmen George

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A Comprehensive Method of Ion Exchange Resins Regeneration and Its Optimization for Water Treatment حسب Al-Asheh, Sameer

"…Water conductivity, as an indicator of regeneration efficiency, was monitored over time at the different conditions and scenario. In general, it was observed that the conductivity decreases with time until one point is reached and then starts to increase as a result of resin saturation. …"
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Investigating the Therapeutic Effects of Small Molecule Imipridones In Pediatric Neuroblastoma حسب El Soussi, Sarra

"…MYCN expression was significantly abrogated in the IMR-32 cell line with either drug treatment. The protein expression of Sox-2, Oct-4, FABP5 and HMGA1 was significantly reduced whereas cleaved PARP1 and caspase-3 and p-H2AX was increased 48 h after drug treatment in the MYCN-amplified IMR-32 cell line. …"
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Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma حسب Peter Kubatka (11008854)

"…However, only in lower dose of sumac were significant decreases in the expression of oncogenic miR210 and increase of tumor-suppressive miR145 (miR21, miR22, and miR155 were not changed) observed. …"

Treatment with decitabine induces the expression of stemness markers, PD-L1 and NY-ESO-1 in colorectal cancer: potential for combined chemoimmunotherapy حسب Nassiba Taib (14557385)

"…</p><h2>Methods</h2><p dir="ltr">We compared the effect of DAC in primary 1076 Col and metastatic 1872 Col cell lines isolated and generated from patients’ tumor tissues. …"