A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T ce... by Abou-Ghazal, Mohamed

“…Experimental Design: The antitumor activities and related mechanisms of WP1066 were investigated both in vitro on melanoma cell lines and in vivo on mice with subcutaneously syngeneic melanoma or with intracerebral melanoma tumors. …”
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Tumor protease-activated fusion toxins by Abi-Habib, Ralph J.

“…In this study, we demonstrate that DTU2GMCSF is highly potent against AML cell lines in vitro and is not toxic to normal cells both in vitro and in vivo. …”
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Selective induction of apoptosis in T-cell acute lymphoblastic leukemia by pristimerin through dual PI3K/AKT pathway inhibition and ROS generation by Shilpa Kuttikrishnan (3520079)

“…Prist significantly increases reactive oxygen species (ROS) levels and depletes glutathione (GSH), leading to mitochondrial dysfunction and cytochrome c release. …”

Protein arginine methyltransferase 5 (PRMT5) activates WNT/β‐catenin signalling in breast cancer cells via epigenetic silencing of DKK1 and DKK3 by Harshita Shailesh (14779408)

“…<p></p><div> <p>Protein arginine methyltransferase 5 (PRMT5) activity is dysregulated in many aggressive cancers and its enhanced levels are associated with increased tumour growth and survival. However, the role of PRMT5 in breast cancer remains underexplored. …”

Inositol 1,4,5-Trisphosphate Receptors in Hypertension by Ali H. Eid (5461829)

“…This involves a phenotypic switch of VSMCs as well as an alteration of cytoplasmic Ca²⁺ signaling machinery, a phenomena tightly related to the aging process. Several lines of evidence implicate changes in expression/function levels of IP₃R isoforms in the development of hypertension, VSMC phenotypic switch, and vascular aging. …”

Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway by Kirti.S. Prabhu (17191231)

“…SNG treatment increased Bax/Bcl-2 ratio, which contributed to a leaky mitochondrial membrane leading to cytochrome c release accompanied by caspase activation. …”

Teachers’ Job Satisfaction in Instructional Delivery Modalities, and the Role of School Leaders: a Study among Selected Private Schools in Abu Dhabi. by YAHYA, AHMAD

“…For example, the interviews recommended that school leaders are invited to build an active channel of communication with their teachers, share the decision-making process with them, decrease the workload, raise the teachers’ autonomy, and establish a remuneration system.…”
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Capacity allocation for voice over IP networks using maximum waiting time models by Sharafeddine, Sanaa

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Effects of Different Processing Methods on the Antibiotic Enrofloxacin Residues Occurrence in Middle Eastern Dairy Products by Haddad, Rita

“…There is a well-reported link between using antibiotics in farming and developing antibiotic resistance, which leads to subsequent human antibiotic treatment failure. …”
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Media, technology use, and attitudes: associations with physical and mental well‐being in youth with implications for evidence‐based practice by Zeeni, Nadine

“…Moreover, social media could be used as a platform for intervention and prevention programs to decrease BID, EDs, depression, and anxiety.…”
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Low Power Wireless Subcutaneous Transmitter by Ali, Mai

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Depression, anxiety and obsessive–compulsive symptoms in relation to nutritional status and outcome in severe anorexia nervosa by Mattar, Lama

“…The present study among severe AN patients investigates links between these psychological variants and nutritional status at admission and subsequent to nutritional rehabilitation. …”
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Ultrasound‑triggered herceptin liposomes for breast cancer therapy by Elamir, Amal

“…Exposing the liposomes to low-frequency ultrasound (LFUS) triggered drug release which increased with the increase in power density. Trastuzumab conjugation resulted in enhancing the sensitivity of the liposomes to LFUS. …”
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Assessment of High-resolution Local Emissions and Land-use in Air Quality Forecasting at an Urban, Coastal, Desert Environment by Christos Fountoukis (4722963)

“…The model’s forecast accuracy was assessed against measurement data from five ground air quality monitoring stations in the greater metropolitan area of Doha over a one-month period. …”

The Effects of Online Formative and Summative Assessment on Test Anxiety and Performance: A Study Among First-Year Undergraduate Students at A Higher Education Institution in Abu D... by ALSUWAIDI, MUNA

“…The presented study was conducted to provide greater insight into the potential positive, neutral and/or negative effects of online formative and summative assessment on test anxiety and performance. …”
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Efficacy And Safety of Cannabidiol on Juvenile Diabetes Outcomes in Male Rats by Awkar, Nai

“…CBD presents desirable effects on hyperglycemia by protecting against oxidative stress and inflammation, having neuroprotective properties, and acting on receptors linked to glycemia. Thus, CBD has the potential to decrease HbA1C in diabetic patients (Diabetes Mellitus type 1) and improve their lives. …”
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Polyaniline/Polystyrene Blends: In-Depth Analysis of the Effect of Sulfonic Acid Dopant Concentration on AC Conductivity Using Broadband Dielectric Spectroscopy by Noora Al-Thani (14147829)

“…The conductivity is discussed in terms of changes in the dielectric permittivity storage <em>(ɛʼ)</em>, loss <em>(ɛʼʼ)</em>, and modulus <em>(Mʼʼ)</em> of the blends over a wide range of temperatures. This is linked to the glass transition temperature of the PANI. …”

Composite hydrogels from carrageenan-cl-carboxymethyl chitosan–PVA incorporated ZiF-8 as dressing material for wound healing applications by Tooba Yasin (19131382)

“…The biocompatibility of the composite hydrogels has been evaluated using fibroblast cell lines (<i>3T3</i>) after different time intervals (24–72 h), and it was found that increasing ZiF-8 caused the mature and spread cell morphology with increasing cell viability and proliferation under controlled in vitro conditions. …”

Direct assembly process by Akle, Barbar J.

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The SREBP-dependent regulation of cyclin D1 coordinates cell proliferation and lipid synthesis by Arwa Aldaalis (13355328)

“…Consequently, inactivation of SREBP1 in human liver and breast cancer cell lines reduces the expression of cyclin D1 and attenuates Rb phosphorylation. …”