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The mechanisms of resistance of anthrax lethal toxin (LeTx)-induced cytotoxicity in AML cells. (c2018)
Published 2018“…Our results indicate that vertical inhibition by SCH772984 rendered the resistant cell lines sensitive to the inhibition of the MAPK-pathway and showed an increased cytotoxic effect once used in combination with anthrax lethal toxin compared to the use of anthrax lethal toxin alone.…”
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162
The Photocatalytic Degradation of 2,3,7,8-Tetrachlorodibenzo-p-Dioxin in the Presence of Silver–Titanium Based Catalysts
Published 2020“…Both catalysts were found to effectively decompose TCDD at 302 nm (lower energy) reaching in between 98–99% degradation after five hours, but AgTiY showed better performance than AgTi at 60 min reaching 91% removal. …”
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163
The July war and its effects on Lebanon’s power-sharing
Published 2007“…On a broader scale, this article helps shed light on the dilemma of power-sharing systems on stormy seas when external conflicts overlap with internal conflict lines.…”
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164
Effectiveness of communication processes in Agile Project Management Approach in the UAE Utility Sector
Published 2023“…Team members should have a voice in the agile project management process, maintain open lines of communication with stakeholders, and discuss problems in a timely manner to increase tolerance and acceptance.…”
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165
Kefir induces cell-cycle arrest and apoptosis in HTLV-1-negative malignant T-lymphocytes
Published 2011“…The percent reduction in proliferation was very significant, and was dose-, and time-dependent. In both cell lines, kefir exhibited its antiproliferative effect by downregulating TGF-α and upregulating TGF-β1 mRNA expression. …”
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166
Anticancer and antioxidant effects of tragopogon porrifolius extract. (c2011)
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167
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The Anti-Tumor Effect of Flaxseed Lignan Derivatives on Different Acute Myeloid Leukemia Cancer Cells
Published 2020“…Moreover, Cell Death ELISA analysis showed a dose-dependent increase in apoptosis, as revealed by an increase in DNA fragmentation. …”
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170
The Impact of Sporting Events on Air Pollution: An Empirical Examination of National Football League Games
Published 2023“…From this, multiple regression analysis was utilized to estimate whether the number of fans was related to changes in air pollution. (3) Results: The regression models found that Ozone and Nitrogen Dioxide levels increased as more individuals attended NFL games. Additional robustness checks and falsification tests suggest that the average NFL event results in an approximately two-percent increase in Ozone levels. (4) Conclusions: The findings from this study contribute to the literature by providing evidence that highly attended sporting events increase pollution levels in the areas near stadiums. …”
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Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015)
Published 2016“…Furthermore, we have attempted to examine the photochemical potential of our metal-organic compound model by combining L-II and L-III in the same metal complex, thus generating four final complexes with differing net charges (from +2 to -4), and examining their activities on a panel of AML cell lines with or without exposure to blue light. Of the four final complexes Ru-II3, Ru-II2-III, Ru-II-III2 and Ru-III3, only Ru-II3 and Ru-II2-III have shown significant activity against all tested cell lines in the dark, whereas photo-activation against ML2 has shown a marked increase of potency of all four complexes, even those shown to be biologically inert in the dark, reaching IC50 values in the nM range. …”
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172
Characterization of the potency and mechanism of action of a novel dual-selective intermolecularly complemented version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Acute...
Published 2023“…However, given that MMP9 was found not to be expressed in the sensitive cell lines, we were able to exclude its expression as a requirement for cytotoxicity. …”
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173
Subarachnoid hemorrhage associated with tadalafil
Published 2011“…Tadalafil is a phosphodiesterase type-5 (PDE5) inhibitor indicated for the treatment of erectile dysfunction. …”
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The Impacts of COVID-19 on the Well-Being of students with SEN in Primary Stage in Dubai Schools
Published 2022“…The current paper aimed to verify the impact of the Covid-19 pandemic on the well-being of a sample of (74) students who were classified by teachers as a student with Special Educational Needs in five of Dubai primary schools. The study methodology depended on the descriptive-analytical approach, the researcher prepared a well-being questionnaire for students with special educational needs SEN, and its validity and reliability were verified. …”
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175
Impacts of On-Grid Solar PV on Distribution Networks and Potential Solutions: A Case Study in the Region of Zahle
Published 2025“…Recent years have witnessed an increase in the installation of solar photovoltaic-based distributed generators or PV DGs mainly in countries with high solar potential such as Lebanon. …”
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176
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Human recombinant arginase I(Co)-PEG5000 [HuArgI(Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human acute myeloid leukemia cells
Published 2013“…In this study, we target arginine auxotrophy of AML cell lines using human arginase I cobalt-PEG5000. HuArgI(Co)-PEG5000 was cytotoxic to all AML cell lines tested. …”
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The Effect of Auditor Characteristics on the Quality of Segment Disclosures of Diversified Firms
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179
The Extent to Which Schools with Mechanistic Structures and their Job Characteristics are Likely to Generate Teachers’ Organisational Commitment: Study Conducted in a Private Schoo...
Published 2020“…Staff are motivated due to their perception of the importance of their roles however an increase in autonomy and authority in decision making as well as diversifying the job skills used during teaching could further increase motivation. …”
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