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STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration
Published 2023“…SOCE has been shown to be important for breast cancer cell migration where knockdown of SOCE components (STIM1 or Orai1) decreases cancer metastasis. Here we show unexpectedly that complete knockout of STIM1 (STIM1-KO) using gene editing in metastatic MDA-MB-231 breast cancer cells results in faster migration and enhanced invasion capacity. …”
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A Transformative State in the Wake of COVID-19: What Is Needed to Enable Innovation, Entrepreneurship, and Education in Qatar?
Published 2022“…Firstly, it aims to present the pillars of the knowledge-based economy and their link to the COVID-19 pandemic. Secondly, the paper aims to analyze the present state of the knowledge-based economy in Qatar, including its strengths, drawbacks, and its prospect for the future. …”
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Wild carrot oil extract is selectively cytotoxic to human acute myeloid leukemia cells
Published 2015“…In this study, we used Daucus carota oil extract (DCOE) to target acute myeloid leukemia (AML) cells. All the AML cell lines tested were sensitive to the extract while peripheral mononuclear cells were not. …”
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187
A new quadratic asymmetric error correction model: does size matter?
Published 2022“…Although our estimation of the Okun’s Law for the USA confirms previous findings on the direction of the sign asymmetry, its reveals that the magnitude of the impact of economic downturns on unemployment decreases faster than the impact of upturns. Forecasting results show that our new model performs better than NARDL.…”
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Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes
Published 2023“…Three DNAJB3 knockout (KO) lines were generated (KO 30, 44 and 47), using CRISPR-Cas9. …”
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“Your taste in fashion is bad”: The role of state of anger in aggressive behavior using the hot sauce paradigm
Published 2020“…<p dir="ltr">This study investigates a mediator of the link between anger induction and subsequent aggressive behavior: the state of anger. …”
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Enterprise risk management in healthcare organizations
Published 2021“…Organizational Risk Management (ERM) emerged as a new approach for managing organizational risks, concentrating on mechanisms to increase corporate governance and risk management in a holistic manner across many enterprise domains. …”
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Association Between Three-Months Vitamin D Supplementation and Depressive Symptomatology incidence among Saudi Arabian Adults
Published 2022“…Objective: According to the World Health Organization (WHO), depression is the main cause of disability worldwide and high risk was noticed in Saudi Arabia. The link between nutrition and mental health has been extensively studied in recent years. …”
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An improved non-dimensional model of wet-cooling towers
Published 2020“…The solution still consists of adjusting the assumed straight air-saturation line to the real air-saturation data, but a new constant (H) is added as well. …”
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195
The Influence of Loneliness and Living Alone on the Quality of Life of the Elderly: Evidence from Europe
Published 2023“…This research indicates a positive correlation between living alone and loneliness, with a greater effect on males, and identifies loneliness as an independent factor decreasing QoL. …”
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Carotid artery revascularization through a radiated field
Published 2003“…Follow-up duplex scans showed asymptomatic recurrent stenosis greater than 60% in 3 patients, 2 of whom with stenosis greater than 80% underwent repeat operation. …”
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Implications of the medication regimen complexity index score on hospital readmissions in elderly patients with heart failure: a retrospective cohort study
Published 2023“…The mean MRCI score for all patients was 33.43. 90% of patients had a high score. There was no link between a high MCRI score and a high 30-day readmission rate (OR 1.02; 95% CI 0.99–1.05; p < 0.13). …”
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A novel multiplex assay for simultaneous quantification of total and S129 phosphorylated human alpha-synuclein
Published 2016“…</p><h3>Conclusions</h3><p dir="ltr">These results demonstrate that our duplex assay for simultaneous quantification is a useful tool to study h-asyn phosphorylation events in biospecimens and will be helpful in studies investigating the precise causative link between post-translational modification of h-asyn and PD pathology.…”
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Intravitreal adalimumab in active noninfectious uveitis
Published 2016“…Seven out of 12 eyes had improvement of ≥2 ETDRS lines. Three out of three eyes had resolution of anterior chamber cells. …”
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