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701
Genome-Based Characterization of Bacterial Pathogens Causing Bloodstream Infection
Published 2024“…Carbapenem resistance and ESBLs were linked to several factors, including variants of NDM such as blaNDM-5 (3/24) and blaNDM-1 (3/24), variants of OXA including blaOXA-1 (9/24) and blaOXA-48 (2/24), and different β-lactamases such as blaCTX-M-15 and blaSHV-11. …”
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masterThesis -
702
Emerging Glycation-Based Therapeutics—Glyoxalase 1 Inducers and Glyoxalase 1 Inhibitors
Published 2022“…<div><p>The abnormal accumulation of methylglyoxal (MG) leading to increased glycation of protein and DNA has emerged as an important metabolic stress, dicarbonyl stress, linked to aging, and disease. …”
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703
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704
Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12
Published 2021“…We find that SCFFBW7-mediated ubiquitylation of FBW7 occurs preferentially on K404 and K412, but is not sufficient for its proteasomal degradation, and in addition requires TRIP12-mediated branched K11-linked ubiquitylation. TRIP12 inactivation causes FBW7 protein accumulation and increased proteasomal degradation of the SCFFBW7 substrate Myeloid Leukemia 1 (MCL1), and sensitizes cancer cells to anti-tubulin chemotherapy. …”
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705
Fracture Behavior of ASTM A633 steel plate specimens with edge crack at tensile test
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conferenceObject -
706
The effect of self-reported flossing behavior on cardiovascular disease events and mortality Findings from the 2009-2016 National Health and Nutrition Examination Surveys
Published 2025“…BackgroundThere is increasing evidence suggesting that daily oral hygiene self-care measures may alleviate cardiovascular disease (CVD) risk. …”
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707
An exploration of intelligence management opportunities for organizations in the UAE: Possible challenges for culture
Published 2017“…Effective national culture is positively Linked to business intelligence. Besides, business intelligence enables organizations in the UAE To gain useful insights on consumer behavior. …”
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708
Immunohistochemical profiling of the heat shock response in obese non-diabetic subjects revealed impaired expression of heat shock proteins in the adipose tissue
Published 2014“…Impairment of heat shock response (HSR) has been already linked to diabetes and insulin resistance as reflected by decrease in heat shock proteins (HSPs) expression. …”
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709
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710
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711
The Activation Kinetics and Crosstalk of RhoGTPases
Published 2020“…Biosensors are two chromophores linked to 2 entities, joined together by a linker which determines their juxtaposition relative to each other, and thus the amount of energy transfer. …”
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masterThesis -
712
Structural and Biophysical Characterization of Stable Alpha-Synuclein Oligomers
Published 2022“…It has been reported that the brains of deceased patients with PD contain high levels of protein oligomers that are cross-linked to these aldehydes. Increasing evidence also suggests that prefibrillar oligomeric species are more toxic than the mature amyloid fibrils. …”
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713
Genomic and pleiotropic analyses of resting QT interval identifies novel loci and overlap with atrial electrical disorders
Published 2021“…These findings provide novel insights into how abnormal myocardial repolarization and increased cardiovascular mortality may be linked.</p><p> </p></div><h2>Other Information</h2> <p> Published in: Human Molecular Genetics<br> License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1093/hmg/ddab197" target="_blank">https://dx.doi.org/10.1093/hmg/ddab197</a></p>…”
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714
Assessment of Qatar’s road network under sea-level-rise scenarios using traffic simulation and graph theory
Published 2025“…High-resolution maps derived from IPCC-AR6 and NOAA projections show that without adaptation measures, SLR may affect approximately 3–11% of land and 2–17% of roads in Qatar, potentially increasing trip durations up to 15 times. Importantly, the estimated impacts are indicative trends rather than definitive outcomes linked to specific emissions scenarios. …”
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715
Metformin Induces Different Responses in Clear Cell Renal Cell Carcinoma Caki Cell Lines
Published 2019“…Persistently activated HIF-1α is associated with increased cell proliferation, angiogenesis, and epithelial–mesenchymal transition (EMT), consequently leading to ccRCC progression and metastasis to other organs. …”
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716
Across the Spectrum In-Depth Review AI-Based Models for Phishing Detection
Published 2024“…<p dir="ltr">Advancement of the Internet has increased security risks associated with data protection and online shopping. …”
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717
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718
Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors
Published 2024“…Furthermore, RFX6 deficiency resulted in the formation of smaller islet organoids due to increased cellular apoptosis, linked to reduced catalase expression, implying a protective role for RFX6. …”
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719
Governing desalination, managing the brine: A review and systematization of regulatory and socio-technical issues
Published 2023“…<p>Desalination has become an attractive option for addressing water needs or solving problems of increasing water scarcity and short-term supply interruptions. …”
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720
The Obesity Paradox in Cancer, Tumor Immunology, and Immunotherapy: Potential Therapeutic Implications in Triple Negative Breast Cancer
Published 2019“…For instance, obesity has emerged as a risk factor for a dampened anti-tumor immune response and increased risk of immunotherapy-induced immune-related adverse events (irAEs) but has also been linked to improved outcomes with checkpoint blockade. …”
