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Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors
منشور في 2024"…Furthermore, induced pluripotent stem cell (iPSC) lines lacking RFX6 were generated using CRISPR/Cas9. …"
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Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4
منشور في 2023"…<p><strong>Poster by Olfa Khalifa (Hamad Bin Khalifa University), Khaoula Errafii (Mohammed VI Polytechnic University), Sama Ayoub (Weill Cornell Medicine - Qatar), Abdelilah Arredouani (Hamad Bin Khalifa University)</strong></p> <p>Background: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide in part due to the obesity epidemic and insulin resistance. …"
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Is extended hepatectomy for hepatobiliary malignancy justified?
منشور في 2004"…Combining extended hepatectomy with another intraabdominal procedure increases the risk of postoperative morbidity.…"
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Evidence-based safety education and training for traffic injury prevention
منشور في 2015"…Stronger GDL programs achieve greater fatality reduction. A systematic review on the effects of post-license driver education, provides no evidence of its effects on preventing road traffic crashes or injuries. …"
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Utilization of the internet for physical activity and diet information and its influence on pregnant women’s lifestyle habits in Qatar
منشور في 2023"…</p><h3>Conclusion</h3><p dir="ltr">Many pregnant women use the internet to access information about PA and diet, and greater use is associated with more positive lifestyle changes. …"
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Aqueous urtica dioica leaves extract inhibits proliferation of acute myeloid leukemia cells in vitro
منشور في 2017"…The decrease was more significant after 72hr with an IC50 at 16mg/ml. …"
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Risk of venous thromboembolism outweighs post-hepatectomy bleeding complications
منشور في 2012"…Conclusions: Contrary to the belief that transient postoperative liver insufficiency is protective, VTE increases with extent of hepatectomy. …"
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Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis
منشور في 2019"…Second, we examined symptom queries preceding queries on the 12-step program at time lags of 0-7 days, 7-14 days, and 14-30 days, where the probability of asking about a medical symptom was greater in the 30-day time window preceding 12-step program information-seeking as compared to all previous times that the symptom was queried.…"
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Circulating exosomal immuno-oncological checkpoints and cytokines are potential biomarkers to monitor tumor response to anti-PD-1/PD-L1 therapy in non-small cell lung cancer patien...
منشور في 2023"…Non-responding patients showed a significant increase in exosomal-PD-L1 (p=0.0078). Furthermore, responding-patients without liver-metastasis showed significant-upregulation of PD-1 (p=0.0070), and downregulation of ULBP1 (p=0.0137) and Siglec-7 (p=0.0037). …"
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A jojoba (Simmondsia chinensis) seed cake extracts express hepatoprotective activity against paracetamol-induced toxicity in rats
منشور في 2022"…In addition, the histological analysis of liver tissues proved significant injury and hepatocellular necrosis. …"
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Location matters: spatial dynamics of tumor-infiltrating T cell subsets is prognostic in colon cancer
منشور في 2024"…We demonstrated an increase in immune cell density and a decrease in the distance of CD3<sup>+</sup>CD8<sup>+</sup> T cells to the nearest tumor cell, in the immune active, ICR High, immune subtypes. …"