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521
Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2...
Published 2024“…For younger demographics (ie, those aged 0–4 years and 5–14 years), risks such as low birthweight and short gestation and unsafe water, sanitation, and handwashing (WaSH) were among the leading risk factors, while for older age groups, metabolic risks such as high SBP, high body-mass index (BMI), high FPG, and high LDL cholesterol had a greater impact. From 2000 to 2021, there was an observable shift in global health challenges, marked by a decline in the number of all-age DALYs broadly attributable to behavioural risks (decrease of 20·7% [13·9–27·7]) and environmental and occupational risks (decrease of 22·0% [15·5–28·8]), coupled with a 49·4% (42·3–56·9) increase in DALYs attributable to metabolic risks, all reflecting ageing populations and changing lifestyles on a global scale. …”
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522
Global, regional, and national prevalence of child and adolescent overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease St...
Published 2025“…From 2022 to 2050, global increases in overweight (not obesity) prevalence are forecasted to stabilise, yet the increase in the absolute proportion of the global population with obesity is forecasted to be greater than between 1990 and 2021, with substantial increases forecast between 2022 and 2030, which continue between 2031 and 2050. …”
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523
Injury burden in individuals aged 50 years or older in the Eastern Mediterranean region, 1990–2019: a systematic analysis from the Global Burden of Disease Study 2019
Published 2022“…<h3>Background</h3><p dir="ltr">Injury poses a major threat to health and longevity in adults aged 50 years or older. The increased life expectancy in the Eastern Mediterranean region warrants a further understanding of the ageing population's inevitable changing health demands and challenges. …”
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524
Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000–17: analysis for the Global Burden of Disease Stud...
Published 2020“…Findings The greatest declines in diarrhoeal mortality were seen in south and southeast Asia and South America, where 54·0% (95% uncertainty interval [UI] 38·1–65·8), 17·4% (7·7–28·4), and 59·5% (34·2–86·9) of units, respectively, recorded decreases in deaths from diarrhoea greater than 10%. …”
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525
Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021
Published 2024“…In this analysis, we assess the current burden of HIV in 204 countries and territories and forecast HIV incidence, prevalence, and mortality up to 2050 to allow countries to plan for a sustained response with an increasing number of people living with HIV globally. …”
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526
The impact of metformin therapy for gestational diabetes on fetal growth in women with risk factors for fetal growth restriction- a registry-based study from Qatar
Published 2023“…</p> <h3>Conclusion</h3> <p>The results of this study suggest that in women with additional risk factors for FGR, the concurrent use of metformin significantly decreases the birthweight and increases the risk for LBW, SFD, PTB and admission to NICU. …”
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527
Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019
Published 2022“…During the same period, LRI episodes and deaths in children younger than 15 years were estimated to have decreased, and the greatest decline was observed for LRI deaths in males younger than 5 years (–70·7% [–77·2 to –61·8]). …”
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528
Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021
Published 2024“…The total DALY burden measured in counts, however, will increase in every super-region, largely a function of population ageing and growth. …”
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529
Rising blood pressure in Bangladesh
Published 2015“…Hypertension and cardiovascular diseases have recently increased in South-East Asia as a result of rapid urbanization, increased life expectancy, and lifestyle changes. …”
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530
Country of birth affects blood pressure in the French hypertensive diabetic population
Published 2015“…In a population of 56,242 individuals living in France, we showed that individuals born in France have significantly different levels of blood pressure (BP) and cardiovascular (CV) risk factors than African and Asian populations born in their own country but living long-term in France (average duration of stay, 5–10 years). …”
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531
Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications
Published 2019“…<i>CCL5</i> variants (<b>rs2107538</b> and <b>rs2280789</b>) were linked to CCL5 serum and mRNA levels. In the TCGA TNBC/Basal-like cohort the <b><i>MAP3K21</i></b><b> </b><b>rs1294255-G</b> allele was associated with a decreased OVS. …”
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532
Nanophthalmos and hemiretinal vein occlusion
Published 2015“…Many risk factors have been linked to retinal vein occlusions (RVOs) whether central or branch retinal vein occlusion. …”
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533
Sulforaphane Delays Fibroblast Senescence by Curbing Cellular Glucose Uptake, Increased Glycolysis, and Oxidative Damage
Published 2018“…SFN delayed senescence by decreasing glucose metabolism on the approach to senescence, exhibiting a caloric restriction mimetic-like activity and thereby decreased oxidative damage to cell protein and DNA. …”
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534
Unraveling the impaired incretin effect in obesity and type 2 diabetes: Key role of hyperglycemia-induced unscheduled glycolysis and glycolytic overload
Published 2024“…Incretin effect impairment is characterized by decreased secretion of incretins from enteroendocrine cells and incretin resistance of pancreatic β-cells. …”
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535
'Ashura in Sydney
Published 2002“…Along with its highly dramatic content, 'Ashura in Sydney is transformed into a practice where the ethnic identity of Shi'i migrants is reproduced and at the same time modified to come to terms with the conditions of living in a new urban environment. In an increasingly globalised world, local and global factors are appropriated in the very process of celebrating 'Ashura and producing the Shi'i identity.…”
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536
Serum 25-hydroxyvitamin D concentrations are inversely associated with body adiposity measurements but the association with bone mass is non-linear in postmenopausal women
Published 2021“…Vitamin D deficiency has been linked to increased adiposity and decreased bone density. …”
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537
Fraud
Published 2017“…It indicates that the existence of fraud in the Middle East is not linked to auditors' misunderstanding of their responsibilities, but might be attributed to the corporate culture and environment.…”
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538
Linear Domesticity: The Hong Kong Single Occupancy Strip
Published 2015“…In reaction to the increasing cost and shrinking size of Hong Kong housing units, the HK:SOS project explores the challenges and limitations of living in minimally sized spaces by producing a linear apartment for a single individual. …”
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539
Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
Published 2024“…Additionally, the distribution of livebirths across the globe is shifting, with a greater proportion occurring in the lowest-income countries. …”
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540
Exploring differences in work values among multigenerational workforce: Leadership approaches in selected higher educational institutions in the UAE
Published 2017“…A similar picture was observed when comparing Generation X-ers with Baby Boomers: salary raise (M=2.99 and M=3.28, p=0.00), pay increases to balance cost of living (M=2.99 and M=3.41, p=0.00) and being paid well (M=2.98 and M=3.41, p=0.00). …”
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