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1141
In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation
منشور في 2013"…We observed ATP depletion under OGD vs. hypoxia and propose that ATP depletion enhances translational suppression, overcoming the selective synthesis of HIF concurrent with global decreases in protein synthesis in hypoxia. Taken together, these findings biochemically characterize a practical reporter for monitoring HIF-1α levels and support a novel model for HIF regulation in an in vitro model of human ischemia.…"
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1142
Maternal Body Mass Index and Recommended Gestational Weight Gain in a Middle Eastern Setting
منشور في 2023"…</p><h3>Results</h3><p dir="ltr">The mean maternal age was 29.7 ± 5.5 years, prepregnancy BMI was 27.5 ± 5.8 kg/m2, GWG was 9.58 kg ± 6.87 kg and gestational age at birth was 38.5 ± 1.9 weeks. In line with IOM recommendations, we found that higher BMI was correlated with decreased GWG and BMI was significantly associated with GWG even after adjusting for maternal age, parity, and infants’ gestational age at birth. …"
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1143
The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR)
منشور في 2023"…Therefore, we investigated the molecular mechanisms accompanied with the epigenetic regulation of NY-ESO-1 in 5-Aza-CdR-treated NCI–H1975 cell line. We showed significant induction of the NY-ESO-1 protein (**p < 0.0097) using Cellular ELISA. …"
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1144
STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration
منشور في 2023"…SOCE has been shown to be important for breast cancer cell migration where knockdown of SOCE components (STIM1 or Orai1) decreases cancer metastasis. Here we show unexpectedly that complete knockout of STIM1 (STIM1-KO) using gene editing in metastatic MDA-MB-231 breast cancer cells results in faster migration and enhanced invasion capacity. …"
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1145
Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression
منشور في 2021"…Herein, fascin ShRNA was used to generate stable fascin knockdown (FSCN1<sup>KD</sup>) in the MDA-MB-231 TNBC cell line and then were subjected to comprehensive mRNA and miRNA transcriptome analysis. …"
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1146
New epidemiology of Staphylococcus aureus infections in the Middle East
منشور في 2014"…Staphylococcus aureus is a bacterial pathogen that is distributed worldwide and represents an increasing problem, both in hospitals and in the community. …"
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1147
Guns and butter? Military expenditure and health spending on the eve of the Arab Spring
منشور في 2019"…Using panel data from 1995 to 2011 – the eve of the Arab uprisings – we find no evidence that increased security needs as measured by the number of domestic terrorist attacks are complemented by increased military spending or more importantly ‘crowd out’ government expenditure on key public goods such as health care. …"
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1148
Sensitivity analysis of work plane illuminance to room surface reflectance values
منشور في 2018"…In this study , the researcher addressed the effects of the wall reflectance through a variety of simulations for the reflectance’s of ceiling , walls and floor , to demonstrate the effects of the surface reflectance on increasing the space illumination , which can play a role as an energy saving as well as cost saving while the high demand of lighting is needed .…"
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1149
Chronic reduction of store operated Ca<sup>2+</sup> entry is viable therapeutically but is associated with cardiovascular complications
منشور في 2022"…They further establish the SOCE hypomorph line as a genetic model to define the therapeutic window of SOCE inhibition and dissect toxicities associated with chronic SOCE inhibition in a tissue-specific fashion.…"
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1150
Breaking the barriers towards large-scale microalgae-based bio-hydrogen production
منشور في 2025"…Results showed that cultivation dominates the process cost: typical biomass costs are $3.54–$5.78/kg in tubular PBRs versus $3.42–$4.13/kg in ORPs; an automation/modularization case decreased microalgae production cost from $89 to $16/kg at ∼200 t/yr. …"
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1151
From student to global citizen
منشور في 2010"…A survey and interviews with students and graduates of LAU were used to gather the data needed. While the majority of the responses approved that LAU’s liberal education program provides the characteristics and skills needed to form a global citizen, the researchers suggest that for a liberal education program to be applied and accepted in a developing country, it has to be adapted to the cultural, financial, and economical needs of that country…"
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1152
Crystallization properties of arsenic doped GST alloys
منشور في 2019"…Optical band gap (E<sub>opt</sub>) values of the as-deposited films show a clear increasing trend; 0.6 eV for GST to 0.76 eV for (GST)<sub>0.85</sub>As<sub>0.15</sub>. The decreases in E<sub>opt</sub> for the samples annealed at higher temperatures shows significant optical contrast between the as-deposited and annealed samples. …"
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1153
In-Person and Online Learning in Communicative Language Teaching Classes: Interaction Levels and Parents’ Perspectives
منشور في 2021"…What are ESL students' needs in distance learning methods? How can their needs be better met? …"
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1154
Improving the Secure Socket Layer Protocol by modifying its Authentication function
منشور في 2017"…If we double the key length in RSA to have more secure communication, then it is known that the time needed for the encryption and decryption will be increased approximately eight times. …"
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conferenceObject -
1155
Improving Healthcare Services by Quality Function Deployment (QFD)
منشور في 2016"…The tools of the Total Quality Management (TQM) have gained high importance due to increasing competitions in the healthcare industry. …"
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1156
Foreign aid and economic development in postwar Lebanon
منشور في 2007"…The second phase from 1997 to the present witnessed a qualitative shift in foreign aid utilization from reconstruction needs towards financial stability and balance-of-payments equilibrium needs. …"
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conferenceObject -
1157
Digital transformation framework
منشور في 2018"…In such firms, different forces are driving the business environment aiming at satisfying the public needs, controlling expenses, and maximizing the use of available assets. …"
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1158
Developing a Sustainable Procurement Action Plan for Public Sector in Ajman
منشور في 2011"…The concept of sustainability is formulated around meeting present generation needs without compromising future generation needs. …"
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1159
A nonlinear PID servo controller for computer hard disk drives
منشور في 2020"…The controller is capable of increasing (decreasing) damping effect when the system output is moving away from (towards) the desired track. …"
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1160
Thermal-aware test scheduling using network-on-chip under multiple clock rates
منشور في 2013"…The increasing trend in the number of cores on a single chip has led to scalability and bandwidth issues in bus-based communication. …"
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