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341
Alterations in Beta Cell Identity in Type 1 and Type 2 Diabetes
منشور في 2019"…Dedifferentiation is well characterized by the decrease in expression of key β cell markers such as genes encoding major transcription factors, e.g., MafA, NeuroD1, Nkx6.1, and Foxo1, and an increase in atypical or “disallowed” genes for β cells such as lactate dehydrogenase, monocarboxylate transporter MCT1, or progenitor cell genes (Neurog3, Pax4, or Sox9). …"
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342
A combined experimental and computational study of the effect of electron irradiation on the transport properties of aromatic and aliphatic molecular self-assemblies
منشور في 2022"…Here we study the effect of electron irradiation on the electronic transport properties of aromatic 5,5′-bis(mercaptomethyl)-2,2′-bipyridine (BPD; HS-CH2-(C5H3N)2-CH2-SH) and electron saturated 1-dodecanethiol (C12; CH3-(CH2)11-SH) molecules self-assembled on an Au (111) surface. …"
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343
Chemical, rheological, and sensory properties of wheat biscuits fortified with local buckwheat
منشور في 2023"…The samples with <i>F</i>. tataricum demonstrated greater amounts of fiber and ash while the samples made of soft wheat flour were rich in carbohydrates. …"
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344
Oxygen targets following cardiac arrest: A meta-analysis of randomized controlled trials
منشور في 2023"…There were no significant differences between the two groups when assessing favorable neurological outcome (RR 1.01, 95% CI: 0.92 to 1.10; I2 = 4%), NSE at 48 h (MD 0.04, 95% CI: −0.67 to 0.76; I2 = 0%), and ICU length of stay (MD −2.86 days, 95% CI: −8.00 to 2.29 days; I2 = 0%).</p> <h3>Conclusions</h3> <p>Conservative oxygen therapy did not decrease mortality, improve neurologic recovery, or decrease ICU LOS as compared to a liberal oxygen regimen. …"
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345
Optimization of Electric Vehicles Wireless Charging
منشور في 2019احصل على النص الكامل
doctoralThesis -
346
Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017)
منشور في 2017"…Sensitivity to HuArgI (Co)- PEG5000-induced arginine deprivation was attributable to the complete dependence on exogenous arginine of two of the five PC cell lines tested and to the partial arginine auxotrophy in combination with fast proliferative requirements of the remaining three cell lines. The lack of ASS-1 expression was demonstrated to be the underlying cause behind complete arginine dependence. …"
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احصل على النص الكامل
احصل على النص الكامل
masterThesis -
347
Impact of severe hypoglycemia on the heat shock and related protein response
منشور في 2021"…At baseline, MAPKAPK5 (p = 0.02) and UBE2G2 (p = 0.003) were elevated and STUB1 decreased (p = 0.007) in T2D. At hypoglycemia: PPP3CA (p < 0.03) was increased and EPHA2 (p = 0.01) reduced in T2D; by contrast, three proteins were reduced in controls [HSPA1A (p = 0.007), HSPB1 (p < 0.02), SMAD3 (p = 0.005)] while only MAPKAPK5 was elevated (p = 0.02). …"
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348
Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis
منشور في 2025"…To characterise the impact on muscle degradation, we tested LAT2 KO mice in cancer‐associated cachexia, streptozocin‐induced Type‐1 diabetes, and ageing models.</p><h3>Results</h3><p dir="ltr">LAT2KO mice experienced a notable reduction in body weight during fasting (WT:14% and LAT2KO:18%, <i>p</i> = 0.02), with a greater reduction in fat mass (0.5‐fold, <i>p</i> = 0.013) and a higher relative retention of muscle mass (1.3‐fold, <i>p</i> = 0.0003) compared with WT. …"
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349
“Enhanced Forced Convection Heat Transfer from a Cylinder using Permeable Fins,
منشور في 2003"…The ratio between the permeable to solid Nusselt numbers increased with Reynolds number and fin height but tended to decrease with number of fins. This ratio was as high as 4.35 at Reynolds number of 150 and a single fin with a nondimensional height of 3.0. …"
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350
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351
A component analysis of positive behaviour support plans
منشور في 2012"…Conclusion Only treatment acceptability was found to be related to decreases in behavioural frequency. No single intervention component was found to have a greater association with reductions in challenging behaviour…"
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احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
article -
352
Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension
منشور في 2023"…<h3>Objective</h3> <p>The study aims to identify and evaluate the relationships between unmodifiable and potentially modifiable factors in hypoglycemic neonates with hypertensive mothers. …"
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353
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354
Zirconium phytate-based proton conductors for high-temperature fuel cell applications
منشور في 2023احصل على النص الكامل
doctoralThesis -
355
Urban Geometry: The Effect of Height Diversity and Buildings Configuration on Thermal Performance and Cooling Load at Urban Scale. A Case Study in Dubai / UAE
منشور في 2018"…This is in addition to the other effect represented by reducing the direct solar access to the building surfaces and decreases the solar energy gained by the buildings envelop through direct radiation. …"
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356
Optimum sizing of steam turbines for concentrated solar power plants
منشور في 2012"…Finally, although the cost of electricity of a CSP plant with capacities greater than 1MWe is significantly reduced to less than 1US$/kWh, currently such technology can only become economically viable through supporting schemes.…"
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357
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358
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359
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360