Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal by Zehra Irshad (18614869)

“…Silencing of HK-2 prevented increased glucose metabolism and MG formation. trans-Resveratrol and hesperetin combination (tRES-HESP) corrected increased MG and glucose metabolism by increasing expression of Glo1 and decreasing expression of HK-2. Increased MG glycation activates the UPR in endothelial cells and thereby may contribute to endothelial cell dysfunction in diabetic vascular disease where tRES-HESP may provide effective therapy.…”

Driving and hypoglycemia by Stephen Beer (5480411)

“…<p dir="ltr">Qatar is one of the 20 countries of the IDF MENA region. Three hundred and eighty seven million people have diabetes worldwide and more than 37 million people in the MENA Region; by 2035 this will rise to 68 million. …”

The promise of tirzepatide: A narrative review of metabolic benefits by Sara Sokary (17337724)

“…<p>Obesity and type 2 diabetes mellites (T2DM) are intertwined epidemics that continue to pose significant challenges to global public health. …”

Correlations between Resting Electrocardiogram Findings and Disease Profiles: Insights from the Qatar Biobank Cohort by Fatima Qafoud (14778571)

“…<h3>Background</h3><p dir="ltr">Resting electrocardiogram (ECG) is a valuable non-invasive diagnostic tool used in clinical medicine to assess the electrical activity of the heart while the patient is resting. …”

Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study by Ayman Al-Dahshan (8962568)

“…<h3>Background </h3><p dir="ltr">Polypharmacy has become a global public health concern particularly in the elderly population. …”

Correction: Prevalence of polypharmacy and the association with non-communicable diseases in Qatari elderly patients attending primary healthcare centers: A cross-sectional study by Ayman Al-Dahshan (8962568)

“…</p><h3>Results </h3><p dir="ltr">Out of 5639 patients screened, 75.5% (95% CI: 74.3–76.6) were exposed to polypharmacy. …”

Bone Benefits of Fish Oil Supplementation Depend on its EPA and DHA Content by Haissam Abou-Saleh (497840)

Women’s empowerment as a determinant of neonatal mortality in Sub-Saharan Africa: a narrative review focused on Nigeria by Joel-Medewase Victor Idowu (22155178)

“…Notably, SSA and South Asia are the regions most lagging behind the Sustainable Development Goal (SDG) 3.2, aiming for <12 neonatal deaths per 1,000 live births by 2030. …”

From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s disease by Ahmad Raza (18205961)

“…One of the notable elements in this connection is the “brain insulin resistance,” most frequently named as “type 3 diabetes,” which impairs glucose metabolism and facilitates amyloid beta (Aβ) plaque synthesis while reducing the action of insulin-degrading enzyme (IDE). …”

Cost-benefit analysis of antimicrobial stewardship program in a cancer setting in Qatar by Dina Abushanab (10696501)

“…The total economic benefit of the ASP maturity was calculated as the sum of the cost savings and the cost avoidance associated with the service minus the operational cost.3 Cost savings were the reduction in therapy cost linked to decreased antimicrobial consumption and resource utilization. …”

Cost-Benefit Analysis of Antimicrobial Stewardship Program in the Adult General Medicine Setting in Qatar by Dina Abushanab (10696501)

“…A total of 500 patients were randomly included (250 in each cohort).</p><h3> Results</h3><p dir="ltr">The operational costs of the program decreased with maturity by cost savings of QAR125 per 100-patient beds per year. …”

Efficacy and safety of using Etelcalcetide for controlling secondary hyperparathyroidism by Tarek Fouda (18472476)

“…The safety and tolerability profiles of Etelcalcetide were assessed.</p><h3>Results</h3><p dir="ltr">Patients within the PTH target range of 150 to 500pg/ml improved from 8% in June 2021 (on Cinacalcet) to 54% in June 2023 (on Etelcalcetide) (p=0 .0032) while patients with PTH above 1,000pg/ml decreased from 50% to 4% during the same period (p=0.00001) (Figure 2). …”

Evaluating the Successful Initiation of a New Dialysate Potassium Management Protocol: “Reduced Emergency Department Admission with Hyperkalemia in Hamad General Hospital Dialysis... by Shajahan Joseph K (18472465)

“…Data were collected and analyzed from ED admission of dialysis patients who had dialysis due to hyperkalemia. </p><h3>Results</h3><p dir="ltr">ED admission of dialysis patients with hyperkalemia which require dialysis reduced from 12% to 0% (Figure 1) and the number of patients who are using low potassium bath of 1.0 mmol/L in Dialysate solution decreased from 56 in Jan 2022 to 7 patients in June 2023 (Figure 2)</p><h3>Conclusion </h3><p dir="ltr">The new potassium protocol was found to be very effective, and has a direct impact on the quality and safety of HD patients. …”

Generalized and pregnancy-related anxiety prevalence and predictors among pregnant women attending primary health care in Qatar, 2018–2019 by Sarah Naja (9954737)

“…<h3>Background</h3><p dir="ltr">Cumulative evidence suggests that early identification of anxiety in pregnancy is important, given that antenatal anxiety has been linked to morbid outcomes in expecting mothers and their offspring. …”

Examining time-to-transport decisions in Emergency Medical Services by Hassan Farhat (9000509)

“…<h3>Background</h3><p dir="ltr">In modern healthcare systems, allocating resources and a patient-centred approach are crucial. …”

Risk Factors for Post-Cesarean, Surgical Site Infections in a Multi-Ethnic Population of Qatar by Sufia Athar (14777830)

“…<h3>Background</h3><p dir="ltr">The surgical site infection (SSI) rate after Cesarean delivery (CD) is considered one of the key performance indicators, not only for developing and under-developed countries but also for developed nations. …”

The cost-benefit associated with the maturity of the Antimicrobial Stewardship Program versus prematurity in Heart Hospital of Hamad Medical Corporation in Qatar by Dina Abushanab (10696501)

“…The most contributing factor was the cost of hospitalization stay (Figure 2).</p><h3>Conclusions</h3><p dir="ltr">M-ASP was associated with decreased operational and resource costs, but this was outweighed by increased costs of resistance and drug use, which could be due to higher sample size in the M-ASP. …”

Ambulatory general urgent clinic: an initiative at the time of COVID-19 pandemic by Abdullah Al-Hothi (18505290)

“…<h3>Background</h3><p dir="ltr">In the ambulatory outpatients’ services, timely assessment of patients leads to earlier recognition of diseases and appropriate treatment. …”

Nurse-Led System-wide Unit-based Hospital Acquired Pressure Injury (HAPI) Reduction Project by Mariam Al-Mutawa (18505317)

“…<h3>Background</h3><p dir="ltr">In Hamad Medical Corporation (HMC) facilities, approximately 45 incidents of Hospital acquired pressure injuries (HAPI) were reported monthly between 2018 and 2021. …”

Accelerating Care: Enhancing Patient Satisfaction through a Quality Initiative in the Obstetrics and Gynaecology Emergency Department at Al Wakra Hospital, Qatar by Lolwa Al Ansari (18466227)

“…<h3>Background</h3><p dir="ltr">Al Wakra Hospital's Obstetrics and Gynaecology Emergency Department (OB ED) faced challenges of overcrowding, and prolonged wait times. …”