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41
Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells
منشور في 2021"…In this study, we investigate the efficacy of two small molecules Ruxolitinib, a JAK/STAT inhibitor, and CHIR-99021, a GSK-3 inhibitor, in targeting pediatric neuroblastoma stem cells by testing them on human MYC-N amplified, IMR-32, and non-MYC-N amplified, SK-N-SH, cell lines. Treating neuroblastoma cells with Ruxolitinib and CHIR-99021 resulted in significant reduction in cellular proliferation, viability, apoptosis and tumorsphere formation capacity in both IMR-32 and SK-N-SH cell lines. …"
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احصل على النص الكامل
masterThesis -
42
Is board compensation excessive?
منشور في 2017"…Based on this, we then calculate whether directors of corporate boards are over- or undercompensated. On average, we find greater evidence of over- rather than undercompensation. …"
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article -
43
Conceptual Skills in Leading Change: A Competence Approach to Public Sector Leadership
منشور في 2019"…In addition to making more conceptual errors than the Expert group, there is insufficient evidence for some specific and elaborated conceptual skills. Finally, the rest of the leaders are categorised as in the Developing level where they adopt some conceptual skills, but several are notably missing. …"
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44
Teachers’ Job Satisfaction in Instructional Delivery Modalities, and the Role of School Leaders: a Study among Selected Private Schools in Abu Dhabi.
منشور في 2022"…The primary teaching modalities that are of the research interest are the face-to-face modular, which represents the traditional teaching module that was commonly applied before the COVID-19 pandemic; the online delivery method which suggests the use of fully distance learning solutions for instruction; and the hybrid learning model, which is a mixture of both the online and face-to-face modules as some students receive instructions from home and at the same time some of their peers are attending the class physically at school. …"
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45
An improved non-dimensional model of wet-cooling towers
منشور في 2020"…The solution still consists of adjusting the assumed straight air-saturation line to the real air-saturation data, but a new constant (H) is added as well. …"
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article -
46
Do high energy-efficient buildings increase overheating risk in cold climates? Causes and mitigation measures required under recent and future climates
منشور في 2022"…While without adequate ventilation, the overheating risk in high-energy-efficient buildings can be higher than old buildings, where decreasing wall and window U-values and infiltration rate has a greater contribution to the increase of indoor temperature, while decreasing window SHGC has a lower contribution to the decrease in indoor temperature compared to the case with adequate ventilation. …"
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47
Aqueous urtica dioica leaves extract inhibits proliferation of acute myeloid leukemia cells in vitro
منشور في 2017"…The decrease was more significant after 72hr with an IC50 at 16mg/ml. …"
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article -
48
Gaining or Losing Team Ball Possession: The Dynamics of Momentum Perception and Strategic Choice in Football Coaches
منشور في 2019"…Nonetheless, both variables displayed asymmetrical effects, in the sense that: (1) the strength of positive PM appeared to be easier to decrease than to increase; and (2) the greater the positive PM (or the negative PM), the lesser (or the greater) the coaches’ tendency to make a change in the organization of their teams. …"
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49
Effect of consanguinity on birth weight for gestational age in a developing country
منشور في 2007"…No significant difference was observed in the decrease in birth weight between the first- and second-cousin marriages. …"
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احصل على النص الكامل
article -
50
The relationship between Determinants of Risk Governance assurance and efficacy of the Public projects in the Government of Dubai from the perspective of Internal Audit Function
منشور في 2018"…These mega-projects may include the construction of major buildings, roads, railway lines and airports. The success of these public initiatives may create the course for the government to decrease its reliance on other sectors. …"
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51
The distribution of toxic sources in Louisiana
منشور في 1993"…The distribution patterns of toxic sources in Louisiana reveal that some communities may be disproportionately exposed to potential environmental risks. …"
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احصل على النص الكامل
احصل على النص الكامل
masterThesis -
52
Coalition game theoretic P2P trading in a distribution network integrity-ensured local energy market
منشور في 2023"…The simulation results confirm that participants, both sellers and purchasers, can decrease their energy costs substantially, and the LEM operator can also secure its margin while the distribution network voltages and line congestion are within the prescribed ranges.…"
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article -
53
Effect of Crude Oil Products on the Geotechnical Properties of Sandy Soil
منشور في 2011احصل على النص الكامل
doctoralThesis -
54
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
منشور في 2019"…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …"
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55
The Assessment of Wind Power for Electricity Generation in Lebanon
منشور في 2010"…Implementing such wind farms would greatly decrease the harmful emission of greenhouse gases produced by the energy sector devoted to electricity generation by fuel (El-Fadel et al., 2003). …"
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article -
56
Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
منشور في 2025"…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…"
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57
Antitumor activity of β-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways
منشور في 2017"…The SW1116 colon cancer cell line was treated with HC (1, 5, 10 and 25 μg/ml) and cell viability was evaluated with WST 1 assay kit. …"
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article -
58
Power System Transient Stability Assessment Based on Machine Learning Algorithms and Grid Topology
منشور في 2023"…Features of transmission line maintenance were used to increase accuracy of estimation. …"
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article -
59
Colloid retention and mobilization mechanisms under different physicochemical conditions in porous media: A micromodel study
منشور في 2021"…However, hydrophilic colloids redeposited on gas-water-solid interfaces or thin water films because of their greater capillary potential. Therefore, greater filtration efficiency is achieved with the hydrophilic colloids compared to the hydrophobic colloids for which the efficiency can be improved by changing the solution chemistry. …"
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60