Role of two efflux proteins, ABCB1 and ABCG2 in blood-brain barrier transport of bromocriptine in a murine model of MPTP-induced dopaminergic degeneration by Milane, Aline

“…Inflammation and Parkinson’s-like lesions induced by MPTP intoxication could lead to modification of drug pharmacokinetics and have clinical consequences, such as neurotoxicity.…”
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Efficient multi-objective neural architecture search framework via policy gradient algorithm by Bo Lyu (16522643)

“…However, differentiable NAS methods encounter challenges when dealing with non-differentiable objectives like energy efficiency, resource constraints, and other non-differentiable metrics, especially under multi-objective search scenarios. …”

Applications of bioconvection for tiny particles due to two concentric cylinders when role of Lorentz force is significant by Lei Zhang (38117)

“…The graphical simulations are performed for flow parameters with specific range like 1≤Re≤5, 1≤Ha≤5, 0.5≤Nt≤2.5, 1≤Nb≤3, 0.2≤Sc≤1.8, 0.2≤Pe≤1.0 and 0.2≤Ω≤1.0. …”

Resilience of UAE high-rise buildings to climate change: Impacts of projected climate changes on annual energy demands. by Sallam, Duaa

“…As global warming is hitting all areas in the entire world, designing and retrofitting buildings based on future weather conditions is essential to avoid early deterioration of buildings especially in countries with high air temperatures like UAE. This motivates the research on finding to most energy efficient solutions that would reduce energy consumption of UAE high-rise buildings in present and future weather conditions. …”
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The burden of prostate cancer in North Africa and Middle East, 1990–2019: Findings from the global burden of disease study by Mohsen Abbasi-Kangevari (9714440)

“…</p><h3>Results</h3><p dir="ltr">The age-standardized rates (95% UI) of PCa incidence, prevalence, and death in 2019 were 23.7 (18.5-27.9), 161.1 (126.6-187.6), and 11.7 (9.4-13.9) per 100,000 population. While PCa incidence and prevalence increased by 77% and 144% during 1990-2019, respectively, the death rate stagnated. …”

Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019 by Razieh, Hassannejad

“…FindingsIn contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. …”
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Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery by Stephen L. Atkin (6684368)

“…<h3>Background: </h3><p dir="ltr">Early metabolic responses following bariatric surgery appear greater than expected given the initial weight loss and coincide with improvement in diabetes. …”

Understanding the phenomenon of saltwater intrusion sourced from desalination plants at coastal aquifers by Farhat Abbas (5480)

“…Column Peclet numbers from the two analyses were identical for potassium ions but those for bromide ions were c. 60% greater from the two-region model than from the convective–diffusion equation. …”

Global, regional, and national mortality among young people aged 10–24 years, 1950–2019: a systematic analysis for the Global Burden of Disease Study 2019 by Joseph L Ward (9715619)

“…Since 1950, deaths in this age group decreased by 30·0% in females and 15·3% in males, and sex-based differences in mortality rate have widened in most regions of the world. …”

Sulforaphane Delays Fibroblast Senescence by Curbing Cellular Glucose Uptake, Increased Glycolysis, and Oxidative Damage by Florence Hariton (18629764)

“…SFN delayed senescence by decreasing glucose metabolism on the approach to senescence, exhibiting a caloric restriction mimetic-like activity and thereby decreased oxidative damage to cell protein and DNA. …”

Health in times of uncertainty in the eastern Mediterranean region, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013 by Mokdad, Ali H

“…However, diarrhoeal diseases were the leading cause of death in Somalia (186·7 deaths per 100 000 people) in 2013, which decreased by 26·9% since 1990. …”
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Impact of the COVID-19 lockdown on lifestyle behaviors and their association with personality among adults in Qatar: A cross-sectional study by Tamara Al-Abdi (8710488)

“…The overall MD adherence decreased during lockdown (5.9 vs. 6.1, p < 0.001). …”

Dynamic Change in Insulin Resistance Induced by Free Fatty Acids Is Unchanged Though Insulin Sensitivity Improves Following Endurance Exercise in PCOS by Myint Myint Aye (6404327)

“…<h3>Background</h3><p dir="ltr">Insulin resistance (IR) is the hallmark of PCOS and it is known that exercise may decrease it. What is unknown is whether exercise may mechanistically alter the underlying IR, attenuating the dynamic lipid induced IR in insulin resistant subjects.…”

Effect of surfactants on the convective heat transfer and pressure drop characteristics of ZnO/DIW nanofluids: An experimental study by Qamar, Adnan

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Evaluation of the durability and shielding properties of high-strength concrete incorporating locally available materials and carbon additives by Othman, Obaida

“…The proposed mixes’ performance measurements include compressive strength, flexural strength, modulus of elasticity, long-term effects (like creep and shrinkage), and electromagnetic shielding. …”
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NLRP7 inter-domain interactions by El Maarri, Osman

“…Mutations in NLRP7 (NOD-like-receptor family, pyrin domain containing 7) are responsible for a type of recurrent pregnancy loss known as recurrent hydatidiform mole (HYDM1). …”
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Deciphering the In vitro Role of microRNAs miR-21-3p and miR-222-5p In the Regulation of Clostridioides difficile Flagellin-Induced Inflammation by Salman, Zeina

“…Flagellin (FliC), a major component of C. difficile flagella, plays a pivotal role in host-pathogen interactions by inducing inflammation via Toll-like receptor 5 (TLR5). MicroRNAs (miRNAs) are critical regulators of inflammation and may serve as therapeutic targets. …”
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Seasonal variations of trace metal chemical forms in bed sediments of a karstic river in Lebanon by Korfali, Samira Ibrahim

“…All readily exchangeable metals decreased in winter and the carbonate bound forms predominated in both seasons. …”
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Road safety and traffic medicine in Iran: Achievements and challenges by A. Motevalian (19807242)

“…The number of annual fatalities, which had been on the rise for several decades, reached to the maximum number of over 27500 deaths in 2005. The number decreased to 23000 in 2010 and less than 18000 in 2013. …”

Nebulized fentanyl for respiratory symptoms in patients with COVID-19 (ventanyl trial) by Nissar Shaikh (11659441)

“…Interventions such as oxygen therapy, oral opiates, and traditional nebulizers like ipratropium bromide and salbutamol are variable in their efficacy, and therapy responses in patients are difficult to predict. …”