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121
Efficiency of Azithromycin-Loaded Lipid Polymer Hybrid Nano-vehicle as a Repurposing formulation in Colon Cancer Management
Published 2025“…It displayed a safe profile on HT29 cell line, with the coated formulation having the lowest IC50= 24.17 μM at 24 hours that even decreases at longer time intervals, which confirms its potential for colorectal cancer management.…”
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122
Location matters: spatial dynamics of tumor-infiltrating T cell subsets is prognostic in colon cancer
Published 2024“…We demonstrated an increase in immune cell density and a decrease in the distance of CD3<sup>+</sup>CD8<sup>+</sup> T cells to the nearest tumor cell, in the immune active, ICR High, immune subtypes. …”
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A Comprehensive Method of Ion Exchange Resins Regeneration and Its Optimization for Water Treatment
Published 2020“…The strong acidic cation polymeric exchanger resin is commercially called MERCK 104765 cation exchanger IV with capacity greater than 3.2 mmol/ml, while the strong basic anion polymeric exchanger resin is commercially called MERCK 104767 anion exchanger III with capacities greater than 1.0 mmol/ml. …”
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125
Hemodynamics of small aneurysm pairs at the internal carotid artery
Published 2012“…The maximum wall shear stress increases for serial aneurysms, but decreases for parallel aneurysms. Interaction between parallel aneurysms is not significant; however, the proximal aneurysm in serial aneurysms may be subject to a greater rupture risk.…”
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126
Trade Flow and Nation Brand Distance: A Structural Gravity Model Approach
Published 2021“…The NBD is calculated based on Country Brand Strength Index (CBSI) which consists of relative values per capita of the statistical data for five different areas that composite the index, which includes the dimensions of exports, tourism, foreign direct investment, immigration, and government environment. …”
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127
The global, regional, and national burden of stomach cancer in 195 countries, 1990–2017: a systematic analysis for the Global Burden of Disease study 2017
Published 2020“…The highest age-standardised incidence rates in 2017 were seen in the high-income Asia Pacific (29·5, 28·2–31·0 per 100 000 population) and east Asia (28·6, 27·3–30·0 per 100 000 population) regions, with nearly half of the global incident cases occurring in China. …”
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128
Targeting the MAP kinase pathway in astrocytoma cells using a recombinant anthrax lethal toxin as a way to inhibit cell motility and invasion
Published 2016“…Cell invasion is a complex process that replies on many signaling pathways including the mitogen-activated protein (MAP) kinase (MAPK). In many cell lines, the use of MAPK-targeted drugs proved to be a potential method to inhibit cancer cell motility. …”
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129
miRNA-dependent regulation of STIM1 expression in breast cancer
Published 2019“…Consistently, overexpression of Ago2 results in decreased STIM1 protein levels in MDA-MB-231 cells. …”
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130
The anti-cancer effect of the pentane fraction of Daucus carota oil extract is mediated through cell cycle arrest and an increase in apoptosis
Published 2013“…We indeed determined that the PF treatment led to a decrease in p-ERK as compared to total ERK levels, whereas the level of phosphorylated Akt was not affected. …”
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131
Prevalence and attributable health burden of chronic respiratory diseases, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017
Published 2020“…However, when accounting for ageing and population growth, declines were observed in age-standardised prevalence (14·3% decrease), age-standardised death rates (42·6%), and age-standardised DALY rates (38·2%). …”
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132
Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma
Published 2020“…In the mouse model, R. coriaria at a higher dose (1%) significantly decreased tumor volume by 27% when compared to controls. …”
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133
Surgical Strategies for Synchronous Colorectal Liver Metastases in 156 Consecutive Patients
Published 2015“…Median numbers of CLMs per patient were 1 in the combined, 3 in the classic, and 4 in the reverse strategy group (p = 0.01 classic vs reverse; p < 0.001 reverse vs combined). …”
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134
Optimisation of PV Cleaning Practices: Comparison Between Performance Based and Periodic Based Approaches
Published 2018“…Periodic based automatic cleaning showed decreases in improvement of between 164.64% to 245.34%. …”
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Supplementation of retrobulbar block with clonidine in vitreoretinal surgery
Published 2011“…The median number of postoperative analgesic requests per patient during the first 24 hours was higher in the control group than the clonidine group [2 (0-3) vs. 1 (0-3); P < 0.001]. …”
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137
The Influence of Loneliness and Living Alone on the Quality of Life of the Elderly: Evidence from Europe
Published 2023“…This research indicates a positive correlation between living alone and loneliness, with a greater effect on males, and identifies loneliness as an independent factor decreasing QoL. …”
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138
Carotid artery revascularization through a radiated field
Published 2003“…Follow-up duplex scans showed asymptomatic recurrent stenosis greater than 60% in 3 patients, 2 of whom with stenosis greater than 80% underwent repeat operation. …”
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139
The effects of a change in the point system on immigration
Published 2016“…In parallel, points for a subjective assessment of “adaptability” were decreased. In line with the initial objective, we find more French-speaking immigrants with bachelor’s degrees, and no worsening in labor market outcomes after the reform. …”
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140
Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
Published 2008“…WP1066 suppressed the phosphorylation of JAK2 and phosphorylation (Tyr705) of STAT3 in all three melanoma cell lines. In addition, WP1066 decreased the level of c-Myc and survivin in melanoma cells in a dose- and time-dependent manner. …”
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