eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways by Zvi Cramer (10742876)

“…Furthermore, we show that hippuristanol perturbs the activation of the STAT3 pathway and expression of STAT3-gene targets such as IL-6. The decreased activation of STAT3, which resulted from a decrease in STAT3 protein expression, was due to the inhibition of STAT3 translation as there were no changes in STAT3 mRNA levels. …”

PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications by Pramod Darvin (153341)

“…Recent studies revealed that enhanced PD-L1 expression in cancer stem cells is linked to immune evasion. Understanding the mechanisms behind this PD-L1 overexpression in cancer stem cells is critical for developing more effective strategies for preventing immune evasion and increasing the efficacy of anti-PD-1/PD-L1 therapy. …”

Effect of phosphorus supplementation on weight gain and waist circumference of overweight/obese adults by Bassil, MS

“…Methods: This is a double-blind, randomized, placebo-controlled trial of 63 adults aged 18–45 years with a body mass index (BMI) of greater than or equal to25 kg m−2 and normal kidney function at the American University of Beirut. …”
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Influence of natural gas composition on adsorption in calcite Nanopores: A DFT study by Elkhansa Elbashier (14152815)

“…Additionally, in all cases, CO₂ has a greater affinity to the surface than CH₄; thus, it is more affected by the surface curvature and energy. …”

Effects of exendin-4 and selenium on the expression of GLP-1R, IRS-1, and preproinsulin in the pancreas of diabetic rats by Barakat, Ghinwa

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Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk by Merhi, Mahmoud

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A modified lipid composition in Fabry disease leads to an intracellular block of the detergent-resistant membrane-associated dipeptidyl peptidase IV by Rizk, Sandra

“…Fabry disease is an X-linked lysosomal storage disorder that leads to abnormal accumulation of glycosphingolipids due to a deficiency of alpha-galactosidase A (AGAL). …”
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Breast cancer cells and bone marrow mesenchymal stromal cells by Faour, Wissam H.

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Hepatitis serology predicts tumor and liver-disease characteristics but not prognosis after resection of hepatocellular carcinoma by Abdalla, Eddie

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Detecting attacks in a cluster based QOS-OLSR protocol. (c2014) by Sanadiki, Hiba

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Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells by Castellino, R.C.

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A Power Ripple Compensator for DC Nanogrids via a Solid-State Converter by Ahmad Khan (6067526)

“…This SSC is often considered as the main DC nanogrid energy control unit that is linking the nanogrid with the main utility AC grid and managing the nanogrid elements. …”

DNA methylation signature in peripheral blood reveals distinct characteristics of human X chromosome numerical aberrations by El Maarri, Osman

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Evaluation of Lycopus uniflorus water extract for anti-inflammatory, anti-ulcerogenic and antioxidant activities by Saade, S.

“…The estimated total phenolic content was 228.5 GAE per gram. The results show that Lycopus uniflorus possesses a potential anti-inflammatory, anti-ulcerogenic and antioxidant activities.…”
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Swimming exercise improves short‐ and long‐term memories: Time‐course changes by Mahmoud A. Alomari (14780446)

“…Young adult Wistar rats were tested for both short-term and long-term memories using the radial arm water maize (RAWM) paradigm following 0, 1, 7, 14, and 28 days of swimming exercise training (60 min per day, 5 days/week)s. The mean total errors on RAWM during the learning phase and memory testing remained the same (p > 0.5) after 1 day of swimming exercise. …”

Crunching the numbers of food poisoning in Qatar by Nature Research (16552612)

“…</p><p>The incidence rate of salmonellosis in Qatar in 2012 was 18.1 per 100,000. This rate is comparable to others in countries such as Canada (19.4/100,000), Poland (22.9/100,000) and the US (16.4/100,000).…”

Shear performance of FRP Reinforced Deep Beams Made of Ultra High Performance Concrete (UHPC) by Salman, Omar

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Orofacial Clefts by El Baba, Nada

“…Through whole genome sequencing, we identified three variant genes, ARHGEF18, CUL7, and EPDR1, that we could link to the cleft phenotype. Through functional assays to test the discrepancy in the behavior of both sets of cells, we assessed proliferation, motility, adhesion, and Rho GTPase activity. …”
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Clinical correlates of white-matter abnormalities on head magnetic resonance imaging by Dimassi, Hani

“…Children with white-matter abnormalities and increased tone had a greater frequency of increased reflexes and tended to have more signal abnormalities than the other groups. …”
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Effects of selenium in comparison to exendin-4 on the expression of GLP-1R, IRS-1 and preproinsulin in the pancreas of diabetic rats by Rizk, Sandra

“…It binds and activates GLP-1R with greater potency than GLP-1 and is used in the treatment of diabetes mellitus. …”
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