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Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017)
Published 2017“…It is one of the deadliest cancer types since its mortality rate per year is nearly equal to its incidence rate. Therefore, there’s a need for more effective and selective therapeutic approaches for targeting PC. …”
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The Pros and Cons of Use of Handheld Electronic Devices During Ward Rounds and the Impact of the COVID-19 Pandemic
Published 2023“…The COVID-19 pandemic led to a decrease in the use of HEDs by both faculty [38(64%)] and PGTs [42(60%)].…”
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BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells
Published 2020“…However, the mechanisms of anti-cancer effect of VCX either as a monotherapy or in combination with other chemotherapeutic agents against breast cancer need investigation.</p><h3>Methods</h3><p dir="ltr">Breast cancer cell lines with different molecular subtypes (MDA-MB-231, MCF7, and SKBR-3) were treated with different concentrations of VCX for indicated time points. …”
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Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-...
Published 2025“…Further studies are needed to assess the impact of these novel therapies on end-organ-specific complications of SCD.…”
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Carotid artery revascularization through a radiated field
Published 2003“…Follow-up duplex scans showed asymptomatic recurrent stenosis greater than 60% in 3 patients, 2 of whom with stenosis greater than 80% underwent repeat operation. …”
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Performance of cold in-place recycling in Nevada
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Infliximab versus ciclosporin in steroid resistant acute severe ulcerative colitis: a model-based cost-utility analysis of data from CONSTRUCT pragmatic trial
Published 2023“…Beyond 2-year trial follow-up, Markov model predicted a decrease in colectomy rate, but it remained slightly higher for ciclosporin. …”
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Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels
Published 2024“…These findings contribute to the growing understanding of nanoparticle toxicity profile and underscore the need for further research to ensure the safe application of nanoparticles in biomedical and other fields.…”
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Chemical, rheological, and sensory properties of wheat biscuits fortified with local buckwheat
Published 2023“…The samples with <i>F</i>. tataricum demonstrated greater amounts of fiber and ash while the samples made of soft wheat flour were rich in carbohydrates. …”
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Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 co...
Published 2024“…Globally between 2010 and 2021, the age-standardised DALY rates for HIV/AIDS decreased by 47·8% (43·3–51·7) and for diarrhoeal diseases decreased by 47·0% (39·9–52·9). …”
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Oxygen targets following cardiac arrest: A meta-analysis of randomized controlled trials
Published 2023“…</p> <h3>Conclusions</h3> <p>Conservative oxygen therapy did not decrease mortality, improve neurologic recovery, or decrease ICU LOS as compared to a liberal oxygen regimen. …”
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Fixed Shading Scenarios to Optimize Lighting Performance and Energy Efficiency in Office Buildings Case Study of Dubai Design District
Published 2021“…In the UAE, the building’s cooling loads account for 60% of the electricity load during the summer in Dubai. Therefore, buildings need a profound and practical solution to reduce the energy consumption caused by the building facades. …”
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