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Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells
Published 2025“…Based on its importance for cancer cells, we aim to investigate the molecular mechanisms that link HSP90 inhibition in colon cancer cells with oxidative stress and mitochondrial stress—related regulators.…”
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302
Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery
Published 2019“…<h3>Background: </h3><p dir="ltr">Early metabolic responses following bariatric surgery appear greater than expected given the initial weight loss and coincide with improvement in diabetes. …”
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303
Understanding the phenomenon of saltwater intrusion sourced from desalination plants at coastal aquifers
Published 2023“…Column Peclet numbers from the two analyses were identical for potassium ions but those for bromide ions were c. 60% greater from the two-region model than from the convective–diffusion equation. …”
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304
Comparative study of the parameters affecting the performance of microchannels' heat exchangers: Latest advances review
Published 2023“…Apart from this, investigating the inlet/outlet arrangement through finite volume method for D‐, I‐, N‐, S‐, U‐, and V‐type arrangements, it is evident that the V‐type sink has overall greater performance. In terms of gravity, it is observed that it has no effect on the performance of microchannel heat exchangers. …”
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Impact of birth weight to placental weight ratio and other perinatal risk factors on left ventricular dimensions in newborns: a prospective cohort analysis
Published 2024“…PW correlated with IVSs (p=0.019), while the longest placental diameter was linked to a decrease in LV internal dimension during diastole (LVIDd) (estimate=−0.07, p=0.039), LV mass (estimate=−0.11, p=0.024), and LV mass/volume (estimate=−0.55, p=0.005).…”
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306
Associating learning technology to sustain the environment through green mobile applications
Published 2019“…Thus, it presents a stepping stone towards linking learning technology while at the same time sustaining the environment.…”
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307
Proteomics Analysis of Human Obesity Reveals the Epigenetic Factor HDAC4 as a Potential Target for Obesity
Published 2013“…In functional assays, our data indicated that ectopic expression of HDAC4 significantly impaired TNF-α-dependent activation of NF-κB, establishing thus a link between HDAC4 and regulation of the immune system. …”
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308
Two-surgeon technique of parenchymal transection contributes to reduced transfusion rate in patients undergoing major hepatectomy
Published 2010“…Parenchymal transection technique was an independent risk factor for perioperative red cell transfusion; the usage of the 2-surgeon technique (combined saline-linked cautery and ultrasonic dissection) was associated with a lower transfusion rate than other techniques, including ultrasonic dissection alone, finger fracture, and stapling (P < .001). …”
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309
Global, regional, and national age-sex-specific burden of diarrhoeal diseases, their risk factors, and aetiologies, 1990–2021, for 204 countries and territories: a systematic analy...
Published 2024“…The most pronounced decline was in children younger than 5 years, with a 79·2% (72·4–84·6) decrease in diarrhoeal deaths. Global YLLs also decreased substantially, from 186 million (147–221) in 1990 to 51·4 million (39·9–65·9) in 2021. …”
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310
Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1<sup>+</sup>/NKX6.1<sup>+</sup> progenitors
Published 2024“…Recent studies have also shown <i>RFX6</i> variants to be linked with type 2 diabetes. Despite RFX6’s known function in islet development, its specific role in diabetes pathogenesis remains unclear. …”
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311
Dual-labeled trastuzumab-based imaging agent for the detection of human epidermal growth factor receptor 2 overexpression in breast cancer
Published 2007“…Results: (DTPA)n-trastuzumab-(IRDye800)m showed significantly greater binding to SKBr3 cells than to MDA-MB-231 cells. …”
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Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019
Published 2022“…During the same period, LRI episodes and deaths in children younger than 15 years were estimated to have decreased, and the greatest decline was observed for LRI deaths in males younger than 5 years (–70·7% [–77·2 to –61·8]). …”
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314
Conflicts Employee-Employee
Published 2012“…The researcher hopes that future researchers may overcome the limitations and identify more effective solutions for decreasing conflicts among employees.…”
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315
A single-institution review of 157 patients presenting with benign and malignant tumors of the ampulla of Vater
Published 2011“…Lymph node involvement was predictive of recurrence and decreased survival. Conclusion Patients with malignant tumors often present with jaundice and larger tumors. …”
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316
Effect of climate change on the annual energy consumption of a single family house in British Columbia
Published 2018“…The Earth is already experiencing some of the effects of climate change, such as rising temperature, more frequent storms, increased precipitation, etc. …”
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The Effect of Atorvastatin (and Subsequent Metformin) on Adipose Tissue Acylation-Stimulatory-Protein Concentration and Inflammatory Biomarkers in Overweight/Obese Women With Polyc...
Published 2019“…Low-grade chronic inflammation of adipose tissue may link PCOS and adverse CVR. In pro-inflammatory states such as PCOS, spontaneous activation of the alternative pathway of complement results in increased generation of acylation stimulating protein (ASP) from adipocytes irrespective of body mass index.…”
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Epibenthic communities from offshore platforms in the Arabian Gulf are structured by platform age and depth
Published 2021“…The lowest number of functional groups occurred in the early ages (2–3 years old), and some groups either increased or decreased their frequency and abundance along the years. …”
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