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A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
Published 2025“…Further, mutational analysis revealed a requirement for both cleavage sites to be intact for increased cleavage rate. Importantly, the inclusion of an Mpro-binding, but non-inhibiting, NB2E3 nanobody at the N-terminal further increased the cleavage rate of the 2× cleavage sequence-containing Mpro biosensor. …”
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Neither Neoadjuvant nor Adjuvant Therapy Increases Survival After Biliary Tract Cancer Resection with Wide Negative Margins
Published 2012“…Immediate resection increased median survival from 42.3 to 53.5 months (p = 0.01). …”
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Three Hundred and One Consecutive Extended Right Hepatectomies
Published 2009“…Postoperative outcomes were similar between patients with increase in sFLR from ≤20% to >20% after PVE and patients with initial sFLR >20%. …”
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Predictive modelling in times of public health emergencies: patients’ non-transport decisions during the COVID-19 pandemic
Published 2025“…<h3>Background</h3><p dir="ltr">During the COVID-19 pandemic, there was a surge in pre-hospital emergency calls due to the increased prevalence of flu-like symptoms and panic related to the pandemic. …”
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An evaluation of recruitment and selection processes in three organizations in the UAE
Published 2011“…The use of formal and informal recruitment and selection procedures for Human Resource Management has increased dramatically in United Arab Emirates (UAE) organizations. …”
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Domain Walls Conductivity in Hybrid Organometallic Perovskites and Their Essential Role in CH<sub>3</sub>NH<sub>3</sub>PbI<sub>3 </sub>Solar Cell High Performance
Published 2015“…We find that due to the charge carrier accumulation, the static conductivity may drastically increase at the domain wall by 3 – 4 orders of magnitude in comparison with conductivity through the bulk of the material. …”
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Preoperative Bevacizumab Does Not Significantly Increase Postoperative Complication Rates in Patients Undergoing Hepatic Surgery for Colorectal Cancer Liver Metastases
Published 2008“…Conclusion Neither the use of BV nor timing of BV administration was associated with an increase in complication rates. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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The anti-cancer effect of the pentane fraction of Daucus carota oil extract is mediated through cell cycle arrest and an increase in apoptosis
Published 2013“…PI/Annexin staining also showed an increase in apoptosis in cells treated with PF. Western blot analysis of several apoptotic proteins also proved a direct activation of PF of the apoptotic pathway in cancer cells. …”
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Online Recruitment Fraud (ORF) Detection Using Deep Learning Approaches
Published 2024“…In recent studies, traditional machine learning and deep learning algorithms have been implemented to detect fake job postings; this research aims to use two transformer-based deep learning models, i.e., Bidirectional Encoder Representations from Transformers (BERT) and Robustly Optimized BERT-Pretraining Approach (RoBERTa) to detect fake job postings precisely. …”
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Increased Frequency of Severe Hypoglycemia with the Modified-Release Gliclazide Compared to Glimepiride in Diabetic Older Adults; Propensity Score-Adjusted Analysis
Published 2022“…<h3>Objective</h3><p dir="ltr">The main aim is to compare the risk of severe hypoglycemia associated with the modified-release (MR) gliclazide against glimepiride in diabetic older adults. …”
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Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection?
Published 2021“…The Renin-Angiotensin System (RAS) is activated in type 2 diabetes (T2D); therefore, the aim of this study was to determine if hypoglycaemia-induced stress in T2D would potentiate serum NRP1(sNRP1) levels, reflecting an increased risk for SARS-CoV-2 infection.</p><h3>Methods</h3><p dir="ltr">A case-control study of aged-matched T2D (n = 23) and control (n = 23) subjects who underwent a hyperinsulinemic clamp over 1-hour to hypoglycemia(<40mg/dl) with subsequent timecourse of 4-hours and 24-hours. …”
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The emergence of new SARS-CoV-2 variant (Omicron) and increasing calls for COVID-19 vaccine boosters-The debate continues
Published 2022“…The emergence of these VOCs (Alpha, Beta, Gamma, and Delta) variants was responsible for new waves of infections across the entire world [3]. The Delta variant was reported to have increased transmissibility, higher viral load [4] and high rates of reinfection [5]. …”
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Deep aging clocks: AI-powered strategies for biological age estimation
Published 2025“…<p>Several strategies have emerged lately in response to the rapid increase in the aging population to enhance health and life span and manage aging challenges. …”
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A Narrative Review on Prevention and Early Intervention of Challenging Behaviors in Children with a Special Emphasis on COVID-19 Times
Published 2022“…<h3>Background</h3><p dir="ltr">COVID-19 and the measures stemming from efforts to control it have affected the psychosocial wellbeing of children and adolescents. …”
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An Efficient Prediction System for Diabetes Disease Based on Deep Neural Network
Published 2021“…This improvement can reduce time, efforts, and labor in healthcare services as well as increasing the final decision accuracy.…”
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Latest Developments in Adapting Deep Learning for Assessing TAVR Procedures and Outcomes
Published 2023“…Recent advancements in the deep learning (DL) domain can offer a real-time surrogate that can render hemodynamic parameters in a few seconds, thus guiding clinicians to select the optimal treatment option. …”
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Unsupervised Deep Learning for Classification Of Bats Calls Using Acoustic Data
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Nonclassicality of open circuit QED systems in the deep-strong coupling regime
Published 2021“…<p dir="ltr">We investigate theoretically how the ground state of a qubit–resonator (Q–R) system in the deep-strong coupling (DSC) regime is affected by the coupling to an environment. …”