A novel inhibitor of signal transducers and activators of transcription 3 activation is efficacious against established central nervous system melanoma and inhibits regulatory T ce... by Abou-Ghazal, Mohamed

“…Long-term survival (>78 days) was observed in 80% of mice with established intracerebral syngeneic melanoma treated with 40 mg/kg of WP1066 in contrast to control mice who survived for a median of 15 days. Although WP1066 did not induce immunologic memory or enhance humoral responses to EGFRvIII, this compound reduced the production of immunosuppressive cytokines and chemokines (transforming growth factor-β, RANTES, MCP-1, vascular endothelial growth factor), markedly inhibited natural and inducible Treg proliferation, and significantly increased cytotoxic immune responses of T cells. …”
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Initial risk assessment for pulmonary hypertension in patients with COPD by Yammine, Joe

“…Background Pulmonary hypertension (PH) is a comorbidity associated with increased mortality in chronic obstructive pulmonary disease (COPD) patients. …”
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Patterns of Rectal Temperature and Shipping Fever Incidence in Horses Transported Over Long-Distances by Yousuke Maeda (18174976)

“…Clinical signs of shipping fever was observed in 25 of the 53 horses (47.2%), of which 10 horses (18.9%) exhibited fever at the end of transportation and 15 horses (28.3%) did not. This showed that horses that develop shipping fever do not necessarily present with fever at the end of transportation. …”

Non-medical cancer support for Qatari women by Nature Research (16552612)

“…<p>Patients' perceptions of the importance of psychosocial support is becoming increasingly important for improving the quality of patient-centred care, but information about the attitudes of female cancer patients in Arab and Muslim populations is scarce. …”

Tranexamic Acid for Traumatic Injury in the Emergency Setting: A Systematic Review and Bias-Adjusted Meta-Analysis of Randomized Controlled Trials by Pieter Francsois, Fouche

“…No compelling evidence of increased vascular occlusive events emerged (OR 0.96, 95% CI 0.73 to 1.27). …”
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Enhancing eggplant (Solanum melongena L.) yield and water use efficiency through optimized irrigation and nitrogen practices in open field conditions by Adewale Suraj, Bello

“…While average fruit weight did not differ significantly across nitrogen levels, the highest fruit yield was recorded under F1 and F2 treatments. …”
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Development and Validation of the Motivation for Tutoring Questionnaire in Problem-Based Learning Programs by Salah Eldin, Kassab

“…In addition, tutoring efficacy scores significantly increased by years of tutoring experience and predicted 38% of the variance in self-rated tutoring skills scores. …”
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Schizophrenia-related dysbindin-1 gene is required for innate immune response and homeostasis in the developing subventricular zone by Abeer R. Al-Shammari (11405339)

“…Immunohistochemistry showed higher Iba1+ immune cell density in the SVZ of Sdy mice than in WT postnatally. PolyI:C did not alter SVZ Iba1+ cell density but increased CD45+/Iba1− cell numbers in the SVZ of Sdy mice. …”

Unpacking the asymmetric impact of exchange rate volatility on trade flows: A study of selected developed and developing Asian economies by Umar Nawaz Kayani (17131781)

“…The non-linear models yielded more significant findings, while the linear models did not indicate any significant effects of exchange rate volatility on trade flows. …”

Cancer cell plasticity: from cellular, molecular, and genetic mechanisms to tumor heterogeneity and drug resistance by Gh Rasool Bhat (13038132)

“…This diversity, known as cancer cell plasticity, confers cancer cells the ability to change in response to their environment, leading to increased tumor diversity and drug resistance. This review explores the intricate landscape of cancer cell plasticity, offering a deep dive into the cellular, molecular, and genetic mechanisms that underlie this phenomenon. …”

An End-to-End Concatenated CNN Attention Model for the Classification of Lung Cancer With XAI Techniques by Fariha Haque (21485518)

“…<p dir="ltr">In the field of medical imaging, deep learning (DL) techniques have made significant contributions to the detection and classification of various cancers. …”

Introducing a Novel Figure of Merit for Evaluating Stability of Perovskite Solar Cells: Utilizing Long Short-Term Memory Neural Networks by Zahraa Ismail (22457644)

“…Future research should prioritize using experimental datasets to achieve more realistic predictions, thereby driving innovation and unlocking the full potential of machine learning and deep learning in optimizing PSC design and performance.…”

Mapping online hate: A scientometric analysis on research trends and hotspots in research on online hate by Ahmed Waqas (687129)

“…Moreover, we identified four main clusters of OHR: (1) <i>Cyberbullying</i>, (2) <i>Sexual solicitation and intimate partner violence</i>, (3) <i>Deep learning and automation</i>, and (4) <i>Extremist and online hate groups</i>, which highlight the cross-disciplinary and multifaceted nature of OHR as a field of research. …”

Osmotically assisted reverse osmosis: Assessing pretreatment on hypersaline produced water by Mashael Al-Maas (14152386)

“…<p>In a rapidly developing oil and gas industry, sustainable management of produced water (PW) is a key challenge. Due to increasing environmental regulations, the industry is driven towards reducing volumes of PW requiring deep well injection and maximizing beneficial reuse. …”

Building thermal resilience framework (BTRF): A novel framework to address the challenge of extreme thermal events, arising from climate change by Mohammad Zaher Serdar (17191381)

“…Moreover, recently, the rate and the impacts of these extremes have increased, despite all the mitigation efforts, necessitating a resilience-based approach to address these challenges stemming from the accelerated global warming and the advent of climate change. …”

A Novel Versatile Framework for Enabling Early Detection of Evolving Network-based Cyberattacks by THOMAS, RAJESH

“…Network-based cyber-attacks have been increasing in scale, frequency and sophistication, posing significant threats to nation states and organizations worldwide. …”
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Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery by Stephen L. Atkin (6684368)

“…<h3>Background: </h3><p dir="ltr">Early metabolic responses following bariatric surgery appear greater than expected given the initial weight loss and coincide with improvement in diabetes. …”

Understanding the phenomenon of saltwater intrusion sourced from desalination plants at coastal aquifers by Farhat Abbas (5480)

“…Column Peclet numbers from the two analyses were identical for potassium ions but those for bromide ions were c. 60% greater from the two-region model than from the convective–diffusion equation. …”

Comparative study of the parameters affecting the performance of microchannels' heat exchangers: Latest advances review by Muhammad Asim (2235472)

“…Apart from this, investigating the inlet/outlet arrangement through finite volume method for D‐, I‐, N‐, S‐, U‐, and V‐type arrangements, it is evident that the V‐type sink has overall greater performance. In terms of gravity, it is observed that it has no effect on the performance of microchannel heat exchangers. …”

Unravelling the predictors of late cancer presentation and diagnosis in Jordan: a cross-sectional study of patients with lung and colorectal cancers by Damsees, Rana

“…For colorectal cancer, those having no previous knowledge about cancers or screening programmes had increased odds of reporting late diagnosis (2.30, 95% CI 1.06 to 4.97). …”
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