PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications حسب Pramod Darvin (153341)

"…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …"

Hydrophobic Ionic Liquids for Efficient Extraction of Oil from Produced Water حسب Liaqat, Shehzad

"…The extraction efficiency was found to increase with increasing cation alkyl chain length from C2 to C10. …"
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Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres حسب Radha, Remya

"…Cytotoxicity assays on human cell lines showed no toxicity towards cells at concentrations of up to 100 µg ml−1 but exhibited increased toxicity at concentrations exceeding 1000 µg ml−1. …"
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Unraveling the future productivity burden of cardiovascular disease in Qatar: Investigating the modifiable risk factors control in type 2 diabetes حسب Dina Abushanab (10696501)

"…The financial value of PALYs was determined based on the gross domestic product (GDP) per full-time worker (i.e. US$80,573). The base-case model estimated the productivity burden of CVD, and interventional scenarios were simulated to assess potential gains resulting from improved control of modifiable risk factors, including reduced incidence of T2D, lower systolic blood pressure (SBP), decreased number of smokers, and reduced total cholesterol. …"

YOLO-DefXpert: An Advanced Defect Detection on PCB Surfaces Using Improved YOLOv11 Algorithm حسب Prabu Selvam (22330264)

"…Compared to the standard YOLOv11 model, the proposed YOLO-DefXpert attained an improvement of 9.3% and 13.2% in mAP50 and mAP95, an 11.25% increase in frames per second, and a 69.85MB decrease in model size. …"

Effectiveness of Positron Emission Tomography for Predicting Chemotherapy Response in Colorectal Cancer Liver Metastases حسب Glazer, Evan

"…For example, a few years ago an extrahepatic metastasis effectively eliminated surgical resection, but a combination of chemotherapeutic options and surgical techniques has expanded the indications for resection and increased the population of patients who may benefit.1,2 Neoadjuvant chemotherapy has increased the resectability rate by 11% to 37%.1 Unfortunately, greater than 80% of patients undergoing hepatic resection will have recurrences, mostly within the first 2 years.2 Nonetheless, the only hope for cure is resection, and prior surgical dogma based on the number of lesions, size of the tumor-free resection margin, and presence of resectable extrahepatic disease must be questioned.3- 5 The current standard approach to surgical planning is contrast-enhanced computed tomography (CT) or magnetic resonance imaging (MRI) for specific tumor characteristics or contraindications to CT.6 Several series showed that focal extrahepatic disease, an isolated pulmonary lesion, can be safely resected, with 5-year survival rates of 29% to 58%.7,8 In 1 series,7 17 of 30 patients required 3 or more resections. …"
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Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans حسب Kirti S. Prabhu (4246144)

"…In addition to cell lines, we assessed the impact of BTZ in an in vivo setting using Caenorhabditis elegans (C. elegans). …"

Open access of evidence‐based publications حسب Yammine, Kaissar

"…We demonstrated that despite a 10‐fold increase in the number of evidence‐based publications in the past 10 years, the rate of free systematic reviews in the general biomedical literature did not change for the last two decades. …"
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Teaching the novel in a university english as a foreign language (EFL) context حسب Bacha, Nahla Nola

"…The aim of the present study is to explore the preliminary  effect of selected novels combined with film and student oral presentations on L1 Arabic EFL learners  use of vocabulary in one 20th Century American Novel course at an English medium university in Lebanon. Two literary essay tests were administered to 25 students, one at the beginning and another at the end of the semester, holistically scored and qualitatively analyzed for vocabulary variety. Main findings indicated that although the holistic scores did not significantly increase, there was use of a more diverse and use of vocabulary on Test 2. Recommendations are made for classroom practice and future research.…"
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The Impact Of E-Leadership On Employees حسب Khoury, Samantha El

"…Work-from-home became an increasingly common business practice and company offices increasingly became unoccupied. …"
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Modulation of Chronic Stress Outcomes by Dietary Sweeteners: A Comparative Study of Sucrose and Aspartame in Mice حسب Akil, Shaymaa

"…In contrast, aspartame did not appear to mitigate behavioral effects of stress. …"
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Thermal Properties of TiO2NP/CNT/LDPE Hybrid Nanocomposite Films حسب Moustafa Zagho (18059980)

"…The TONP incorporation did not modify the Xc %. Moreover, thermal gravimetric analysis (TGA) thermograms confirmed the increased thermal stability after introducing CNTs and hybrid fillers compared to TONP incorporation.…"

Comparative Evaluation of Membrane Filtration on the Tertiary Treatment of Synthetic Secondary Effluent حسب Mortula, Maruf

"…Moreover, as pressure increased there was a slight increase in the efficiency. …"
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The Influence of Transformational and Transactional Leadership on Employee Performance and Organizational Commitment A Case Study in the UAE Public Sector حسب Abdalla, Hani Gawdat

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Cooperative Learning and Second Language Acquisition: Learner Empowerment in the UAE حسب Iyer, Rekha Venkatraman

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The distribution of toxic sources in Louisiana حسب Djoundourian, Salpie Sarkis

"…Furthermore, the greater the percentage of blacks in a community, the greater the reductions in discharges. …"
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Road deaths and injuries in India: Action required on the five pillars of road safety حسب Gopalakrishna Gururaj (19807233)

"…In 2014, 141,000 persons died and 4,77,731 persons were injured as per official reports (1). …"

Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion حسب Khoury, Nathalie

"…Kefir's anti‑cancer potential was tested on CRC cell lines, Caco‑2 and HT‑29, through cytotoxicity, proliferation, and apoptotic assays. …"
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Risk Factors for Post-Cesarean, Surgical Site Infections in a Multi-Ethnic Population of Qatar حسب Sufia Athar (14777830)

"…In our hospital, the SSIs after CD were noted to increase in 2016 and first quarter of 2017. One of the methods implemented for SSI reduction included identifying modifiable risk factors.…"

Evaluation of heavy metals content in dietary supplements in Lebanon حسب Korfali, Samira Ibrahim

"…Results: Some samples had levels of metals above their maximum allowable levels (Fe: 24%, Zn: 33%, Mn: 27%, Se: 15%, Mo: 12% of samples), but did not pose any health risk because they were below permitted daily exposure limit and recommended daily allowance except for Fe in 6% of the samples. …"
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