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541
Single-Cell Transcriptome Analysis Revealed Heterogeneity and Identified Novel Therapeutic Targets for Breast Cancer Subtypes
Published 2023“…Given the aggressive nature and lack of targeted therapies for TNBC, elevated expression of ENO1, FDPS, CCT6A, TUBB2A, and PGK1 predicted worse relapse-free survival (RFS) in basal BC (n = 442), while elevated expression of ENO1, FDPS, CCT6A, and PGK1 was observed in the most aggressive BLIS TNBC subtype. …”
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542
A multi-targeted approach to identify potential flavonoids against three targets in the SARS-CoV-2 life cycle
Published 2022“…These observations were complimented by the 100 ns molecular dynamics simulation and binding free energy analysis, which showed a considerable stability of docked bioflavonoids in the active site of SARS-CoV-2 target proteins. …”
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543
Attitudes, motivators, and barriers toward influenza vaccination for children: a study from a conflict-ridden country
Published 2024“…<h3>Background</h3><p dir="ltr">Despite the increased recommendations for influenza vaccination, particularly among high-risk groups such as young children, Yemen lacks an influenza vaccination program, and the influenza vaccine is not included in the national immunization regime. …”
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544
VisioDECT: a novel approach to drone detection using CBAM-integrated YOLO and GELAN-E models
Published 2025“…Our article proposes a vision-based system for real-time drone identification and classification utilizing YOLOv5, YOLOv8, and GELAN-E deep learning models, enhanced with novel attention mechanisms and interpretability techniques. …”
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545
Artificial intelligence-based methods for fusion of electronic health records and imaging data
Published 2022“…We found that studies fusing imaging data with EHR are increasing and doubling from 2020 to 2021. In our analysis, a typical workflow was observed: feeding raw data, fusing different data modalities by applying conventional machine learning (ML) or deep learning (DL) algorithms, and finally, evaluating the multimodal fusion through clinical outcome predictions. …”
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546
Dual-labeled trastuzumab-based imaging agent for the detection of human epidermal growth factor receptor 2 overexpression in breast cancer
Published 2007“…Results: (DTPA)n-trastuzumab-(IRDye800)m showed significantly greater binding to SKBr3 cells than to MDA-MB-231 cells. …”
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547
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548
Trends in prescribing and outcomes in obese versus non-obese patients receiving rivaroxaban therapy: an observational study using real-world data
Published 2023“…</p><h3>Results</h3><p dir="ltr">The number of patients initiated on rivaroxaban therapy significantly increased from 152 (3.3%) in 2015 to 1342 (28.9%) in 2020 (p <0.001). …”
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549
Ablation of LAT2 Transporter Causes Intramuscular Glutamine Accumulation and Inhibition of Fasting‐Induced Proteolysis
Published 2025“…Further, chronic Gln accumulation and decreased proteolysis were found to induce the early onset of an age‐related muscle phenotype.…”
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550
Urban Geometry: The Effect of Height Diversity and Buildings Configuration on Thermal Performance and Cooling Load at Urban Scale. A Case Study in Dubai / UAE
Published 2018“…The variation along the short direction of the urban block has a greater positive effect and the saving in cooling energy consumption reaches 4.6 %. …”
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551
Experimental and modeling analysis of p-type Bi<sub>0</sub>.<sub>4</sub>Sb<sub>1</sub>.<sub>6</sub>Te<sub>3</sub> and graphene nanocomposites
Published 2022“…The synthesized pristine Bi<sub>0.4</sub>Sb<sub>1.6</sub>Te<sub>3</sub> and 0.05wt% GNS/Bi<sub>0.4</sub>Sb<sub>1.6</sub>Te<sub>3</sub> nanocomposites at different addition times of GNS have exhibited a single-phase and artifact-free bulk nanocrystalline Bi<sub>0.4</sub>Sb<sub>1.6</sub>Te<sub>3</sub> with nanocrystals size of 17 nm. …”
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552
Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications
Published 2019“…High expression of <i>CCL5</i> in breast tumors was significantly associated with an increased OVS in all BC patients, but particularly in TNBC/Basal-like patients. …”
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553
Novel proteins implicated in lipid metabolism disorders
Published 2016“…</p><p>ANGPTL4 is a protein that is activated during fasting, decreasing the release of free fatty acids from circulating triglyceride-rich lipoproteins. …”
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554
Phase state of secondary organic aerosol in chamber photo-oxidation of mixed precursors
Published 2021“…Although less important than RH and MR<sub>org/inorg</sub>, the SOA composition plays a second-order role, with differences in the liquid-to-nonliquid transition at moderate MR<sub>org/inorg</sub> of ∼ 1 observed between biogenic-only (anthropogenic-free) and anthropogenic-containing VOC systems. Considering the combining role of the RH and chemical composition in aerosol phase state, the BF decreased monotonically with increasing hygroscopic growth factor (GF), and the BF was ∼ 0 when GF was larger than 1.15. …”
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555
Why Don’t People Ride Bicycles in High-Income Developing Countries, and Can Bike-Sharing Be the Solution? The Case of Qatar
Published 2020“…When asked about motivators for cycling, the results revealed that improving intersections, adding additional infrastructure facilities, planting trees for shading, affordable bicycles, and campaigns targeting potential cyclists and drivers are needed in order to increase cycling. …”
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556
Can Ease of Doing Business Shorten the Distance and Attract Foreign Direct Investment
Published 2021“…Abstract Due to the accelerating pace of globalization, Multinational Enterprises (MNEs) have increasingly employed foreign direct investment (FDI) to enter foreign markets. …”
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557
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558
Liver resection for liver metastases from nondigestive endocrine cancer
Published 2012“…After median follow-up of 20 months (range, 1–144), the 5-year overall and recurrence-free survival rates were 58% and 37%, respectively. …”
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559
Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4
Published 2023“…Then starved the cells for 6h in DMEM containing 1% fatty-acid-free bovine serum albumin. Following the starvation, a 16h incubation in DMEM containing increasing concentrations of OA (0–500 µM) at 37 °C was performed, and steatosis was quantified by triglycerides quantification, Bodipy staining, and quantification of the expression of perilipin genes family. …”
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560
Seismic Site Response, Analysis and Characterization of Major Cities in UAE
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