Modeling circadian clock–cell cycle interaction effects on cell population growth rates حسب El Khatib, N.

"…Particularly, we show that Cry 1, Cry 2 mutations decrease the growth rate of cells, Per 2 mutation enhances it and Bmal 1 knockout increases it for autonomous periods of the cell cycle less than 21 h and decreases it elsewhere. …"
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Dual Targeting of Matrix Metalloproteases and the MAPK Pathway in Acute Myeloid Leukemia Cells Using an MMP-activated anthrax lethal toxin (PrAgL1/LF) حسب Al Saneh, Ahmad

"…Our results demonstrate that vertical inhibition does offer increased potency in comparison to single targeting of the MAPK pathway when working with sensitive cell lines that are dependent on the cascade. …"
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Trade Flow and Nation Brand Distance: A Structural Gravity Model Approach حسب AL BESHER, HUDA ISMAIL

"…The results on the impact of NBD on FTA and trade flows provides some interesting insights as the there is a negative and significant moderation impact of NBD on the relationship between FTA and both export and import volume which suggest that a decrease of NBD will increase the effect of FTA on trade flow. …"
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Performance assessment of an integrated absorption cooling-hydrogen liquefaction system using geothermal energy حسب Gadalla, Mohamed

"…The results show that the mass of hydrogen gas pre-cooled by the absorption system per unit mass flow rate of geothermal water flowing through the system (n) and the amount of hydrogen liquefied per unit mass flow rate of geothermal water flowing through the system (y) increase with an increase in the geothermal source temperature. …"
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Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro حسب Rizk, Sandra

"…However, due to its dose-limiting cytotoxicity, combination treatments have been investigated to achieve better outcome with less side effects. Andrographolide (AG) is a plant-derived compound that was reported to induce apoptosis and autophagy in acute myeloid leukemia cell lines. …"
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An improved non-dimensional model of wet-cooling towers حسب QURESHI, BILAL AHMED

"…The first method shows a maximum decrease of 4.4 per cent in error, whereas in the second method, the maximum error was found to be 3.3 and 6.8 per cent when the inlet air was unsaturated and saturated, respectively. …"
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Characterization of the potency and mechanism of action of a novel dual-selective intermolecularly complemented version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Acute... حسب Farhat, Mirna

"…The sensitivity of AML cells to IMC/FP59 did not depend on the basal levels of expression of uPAR and MMPs (MMP2 and MMP9). However, given that MMP9 was found not to be expressed in the sensitive cell lines, we were able to exclude its expression as a requirement for cytotoxicity. …"
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Optimisation of PV Cleaning Practices: Comparison Between Performance Based and Periodic Based Approaches حسب ALHAJERI, RASHED ABDULLA

"…Although the biggest costs involved in this technology is the installation/capital costs, the subsequent running costs (although less than traditional sources of energy) such as cleaning and maintenance can increase or decrease the feasibility of these panels. …"
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Annona cherimola Seed Extract Activates Extrinsic and Intrinsic Apoptotic Pathways in Leukemic Cells حسب Haykal, Tony

"…Treatment with an A. cherimola seed ethanolic extract promotes a dose- and time-dependent inhibition of the proliferation of various AML cell lines, but not MSCs. Positive Annexin V staining, as well as DNA fragmentation, confirm an increase in apoptotic cell death by upregulating the expression of pro-apoptotic proteins which control both intrinsic and extrinsic pathways of apoptosis. …"
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Annona cherimola Seed Extract Activates Extrinsic and Intrinsic Apoptotic Pathways in Leukemic Cells By Peter Nasr A thesis حسب Nasr, Peter

"…Treatment with an A. cherimola seed ethanolic extract promotes a dose- and time-dependent inhibition of the proliferation of various AML cell lines, but not MSCs. Positive Annexin V staining, as well as DNA fragmentation, confirm an increase in apoptotic cell death by upregulating the expression of pro-apoptotic proteins which control both intrinsic and extrinsic pathways of apoptosis. …"
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Effects of short term genotropin (rgGH) subcutaneous injection on active ghrelin concentration in rat plasma, stomach, kidney & pancreas. (c2007) حسب Haddad, Haytham

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A urokinase-activated recombinant diphtheria toxin targeting the granulocyte-macrophage colony-stimulating factor receptor is selectively cytotoxic to human acute myeloid leukemia... حسب Abi-Habib, Ralph J.

"…The activity of this toxin was then tested on a larger group of 13 human AML cell lines; 5 of the 13 cell lines were sensitive to DTU2GMCSF. …"
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Characterizing the dynamics of climate and native desert plants in Qatar حسب Meshal Abdullah (17746950)

"…Optimal rainfall events per year ranged from 10 to 15, with 70 mm being the threshold for healthy vegetation growth. …"

Public motives and willingness to participate in first-in-human clinical trials in Saudi Arabia: A new era in the making حسب Almutairi, Adel F.

"…Higher attitudinal scores were reported by those who perceived healthcare services as good/excellent (adj.P < 0.001), and by those who had less concerns (adj.P = 0.005). Less educated participants were 1.75 [1.04–2.93] times more likely to enroll in future clinical trials, adj.P = 0.035. …"
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Malva pseudolavatera Leaf Extract Promotes ROS Induction Leading to Apoptosis in Acute Myeloid Leukemia Cells In Vitro حسب El Khoury, Marianne

"…Treatment of AML cell lines with M. pseudolavatera methanolic leaf extract showed a dose- and time-dependent inhibition of proliferation and a dose-dependent increase in apoptotic hallmarks such as an increase in phosphatidylserine on the outer membrane leaflet and membrane leakage in addition to DNA fragmentation. …"
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Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes حسب Maryam Aghadi (17128819)

"…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …"

The downside of cardiac devices insertion حسب Nature Research (16552612)

"…Echocardiography will be performed at a mean of one year post-pacemaker insertion to assess whether there is an increase in TR after lead implantation. Given that patient follow-up after pacemaker insertion is still ongoing, it remains unclear whether permanent implantation of a cardiac device increases the risk of TR. …"

Targeting human acute myeloid leukemia cells using human recombinant arginase I (Co) - PEG5000 [HuArgl (Co) - PEG5000] - induced arginine depletion. (c2013) حسب Tanios, Rita Farid

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The antioxidant and anticancer effects of Wild Carrot oil extract حسب Shebaby, Wassim Nasri

"…The effect of DCOE on the cell lines exhibited time and dose-dependent responses. …"
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Do high energy-efficient buildings increase overheating risk in cold climates? Causes and mitigation measures required under recent and future climates حسب Mutasim Baba, Fuad

"…While without adequate ventilation, the overheating risk in high-energy-efficient buildings can be higher than old buildings, where decreasing wall and window U-values and infiltration rate has a greater contribution to the increase of indoor temperature, while decreasing window SHGC has a lower contribution to the decrease in indoor temperature compared to the case with adequate ventilation. …"
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