The Role of Epidermal Growth Factor Receptor Family of Receptor Tyrosine Kinases in Mediating Diabetes-Induced Cardiovascular Complications by Bara A. Shraim (11753786)

“…It is the complications of diabetes such as cardiovascular, renal, neuronal and ocular dysfunction that lead to increased patient morbidity and mortality. Of these, cardiovascular complications that can result in stroke and cardiomyopathies are 2- to 5-fold more likely in diabetes but the underlying mechanisms involved in their development are not fully understood. …”

Hypoxia silences retrotrapezoid nucleus respiratory chemoreceptors via alkalosis by Basting, Tyler M.

“…RTN neurons are silent above pHa 7.5 and increasingly active below this value. During hyperoxia, RTN activation maintains breathing despite the inactivity of the carotid bodies. …”
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Strong association of common variants in the IGF2BP2 gene with type 2 diabetes in Lebanese Arabs by Nemr, Rita

“…Taking the common rs4402960/rs1470579 GA haplotype as reference, multivariate analysis confirmed the positive association of TC (P = 0.009; OR, 1.43; 95%CI, 1.09–1.87), and TA (P < 0.001; OR = 5.49; 95%CI = 2.09–14.39) haplotypes with increased T2DM risk. …”
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Prevalence and factors associated with falls in older adults in a Middle Eastern population: a retrospective cross-sectional study by D.A. Alsayed Hassan (19724410)

“…Compared to individuals aged 60–69 years, individuals aged 70–79, 80–89, and 90–99 had increased odds of falls by 1.6 (95% CI 1.5, 1.8), 2.5 (95% CI 2.2, 2.8), and 2.6 (95% CI 2.0, 3.3), respectively. …”

Risk of Malignancy in Indeterminate Liver Nodules Among Patients with Cirrhosis: A Retrospective Cohort Study by Yousef Yahia (19756989)

“…Nodules larger than 1–2 cm or LI-RADS 3 lesions pose increased risk for HCC. Enhanced surveillance is necessary given the lack of clear management guidelines.…”

Rapid mercury removal using living indigenous microalgal communities for water treatment applications by Amr Nasr Fekry (22521185)

“…Kinetic studies showed superior correlation with the pseudo-second-order model (R² > 0.996), with rate constants decreasing systematically from 767.5 to 216.0 g/mg·min as concentration increased, suggesting secondary chemical interactions may also contribute to the overall mechanism. …”

General developmental health in the VPA-rat model of autism by Khazen, Georges

“…In rats, early embryonic exposure, around the time of neural tube closure, leads to autism-like anatomical and behavioral abnormalities in the offspring. Considering the increasing use of the VPA rat model, we present our observations of the general health of Wistar dams treated with a single intraperitoneal injection of 500 or, 600 mg/kg VPA on embryonic day E12.5, as well as their male and female offspring, in comparison to saline-exposed controls. …”
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Pattern of Postoperative Mortality After Esophageal Cancer Resection According to Center Volume by Markar, Sheraz

“…Results The 30-day and in-hospital POM rates were 5.0 and 7.3 %, respectively. Pulmonary complications were the most common, affecting 38.1 % of patients, followed by surgical site infection (15.5 %), cardiovascular complications (11.2 %), and anastomotic leak (10.2 %). …”
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Reply to Comments by Kakkar and Dahiya by Chahine, Elias B.

“…Initial reports describing the use of bedaquiline in patients with MDR-TB and extensively drug-resistant TB are promising.3,4 Fortunately, the World Health Organization (WHO) has recently issued an interim policy guidance recommending that bedaquiline may be added to a WHO-recommended regimen in adult patients with MDR-TB when an effective regimen containing 4 second-line drugs in addition to pyrazinamide cannot be designed, and when there is documented evidence of resistance to any fluoroquinolone in addition to multidrug resistance.5 Similarly, the Centers for Disease Control and Prevention (CDC) has also issued provisional guidelines recommending that bedaquiline may be used for 24 weeks in adults with laboratory-confirmed pulmonary MDR-TB when an effective regimen cannot otherwise be provided; on a case-by-case basis in children, persons with HIV, pregnant women, persons with extrapulmonary MDR-TB, and patients with comorbidties when effective regimen cannot otherwise be provided; and on a case-by-case basis for durations longer than 24 weeks when an effective regimen cannot be provided.6 Both WHO and CDC emphasize the need for careful monitoring of patients on bedaquiline therapy for safety concerns.5,6 Until further data become available, the authors believe that patients who meet eligible criteria according to current guidelines may benefit from bedaquiline therapy with careful monitoring for potential side effects and drug interactions.…”
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Patterns of pain medication use in older individuals with cardiovascular disease by Kabbara, Wissam K.

“…Twelve (5.3%) patients received duplication of pain medications, while 14 (5.7%) received an inappropriate combination of pain medications. …”
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Teaching Benign Paroxysmal Positional Vertigo to Emergency Medicine Residents by Using Gagne’s Nine Steps of Instructional Design by Khalid Bashir (9300293)

“…The median score before the course for the DH test was 2 (1.7– 3.0) and improved to 5(4.0– 5.0). Similarly, CR’s median score improved from 2 (1.0– 2.3) to 5 (4.7– 5.0). …”

Unmasking Hidden Gluten: Evaluating the Compliance of Gluten-Free Products and Consumer Exposure in Lebanon by Assi, Ranim Mohammed

“…Gluten was quantified with the RIDASCREEN® R5 ELISA; with levels > 20 ppm were deemed non-compliant. …”
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Imatinib blocks migration and invasion of medulloblastoma cells by concurrently inhibiting activation of platelet-derived growth factor receptor and transactivation of epidermal gr... by Abouantoun, Thamara J.

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Metabolic signature of obesity-associated insulin resistance and type 2 diabetes by Haya Al-Sulaiti (5449256)

“…Furthermore, our data confirmed changes in metabolic markers of liver disease, vascular disease and T2DM, such as 3-hydroxymyristate, dimethylarginine and 1,5-anhydroglucitol, respectively.</p><h3>Conclusion</h3><p dir="ltr">This pilot data has identified phospholipid metabolites as potential novel biomarkers of obesity-associated insulin sensitivity and confirmed the association of known metabolites with increased risk of obesity-associated insulin resistance, with possible diagnostic and therapeutic applications. …”

Anabolic steroids-induced delirium by Mohamed Adil Shah Khoodoruth (14589828)

“…He was discharged on haloperidol 7.5 mg and quetiapine 700 mg daily.</p><h3>Conclusion</h3><p dir="ltr">The purpose of this case report is to emphasize on the neuropsychiatric effects and management of anabolic steroids manifested by delirium, increased aggression, hostility, and destructive impulses.…”

Enhanced nucleate boiling heat transfer on bubble-induced assembly of 3D porous interconnected graphene oxide/silver nanowire hybrid network by Nurettin Sezer (14778217)

“…<p>Due to an increasing trend of size diminution, integration, and multifunctionality, the heat load on electronic devices is constantly increasing. …”

Postprandial hyperaminoacidaemia overcomes insulin resistance of protein anabolism in men with type 2 diabetes by Bassil, M.

“…Hyper-2 results were compared with those of diabetic men whose plasma glucose was lowered to 5.5 mmol/l and fasting aminoacidaemia maintained during the hyperinsulinaemic clamp (Hyper-1). …”
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Prescription patterns of benzodiazepines in the Lebanese adult population by Ramadan, Wijdan H.

“…Among those using BDZs for at least 1 month, 35.5% increased the dose with time. Thirty-three percent reported having experienced side effects. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle by Jinit Masania (7164239)

“…From this and previous transcriptomic studies, signaling involved in enhanced removal of MG-modified protein is likely increased HSPB1-directed HUWE1 ubiquitination through eIF2α-mediated, ATF5-induced increased expression of HSPB1. …”

Monitoring polycyclic aromatic hydrocarbons in the Northeast Aegean Sea using Posidonia oceanica seagrass and synthetic passive samplers by Pavlopoulos, Kosmas

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