-
241
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
Published 2019“…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …”
-
242
Hydrophobic Ionic Liquids for Efficient Extraction of Oil from Produced Water
Published 2022“…The extraction efficiency was found to increase with increasing cation alkyl chain length from C2 to C10. …”
Get full text
article -
243
Lung nodule classification utilizing support vector machines
Published 2002“…Recently, support vector machines (SVMs) had received increasing attention for pattern recognition. The advantage of SVM lies in better modeling the recognition process. …”
Get full text
Get full text
article -
244
Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres
Published 2024“…Cytotoxicity assays on human cell lines showed no toxicity towards cells at concentrations of up to 100 µg ml−1 but exhibited increased toxicity at concentrations exceeding 1000 µg ml−1. …”
Get full text
article -
245
Unraveling the future productivity burden of cardiovascular disease in Qatar: Investigating the modifiable risk factors control in type 2 diabetes
Published 2025“…The financial value of PALYs was determined based on the gross domestic product (GDP) per full-time worker (i.e. US$80,573). The base-case model estimated the productivity burden of CVD, and interventional scenarios were simulated to assess potential gains resulting from improved control of modifiable risk factors, including reduced incidence of T2D, lower systolic blood pressure (SBP), decreased number of smokers, and reduced total cholesterol. …”
-
246
YOLO-DefXpert: An Advanced Defect Detection on PCB Surfaces Using Improved YOLOv11 Algorithm
Published 2025“…Compared to the standard YOLOv11 model, the proposed YOLO-DefXpert attained an improvement of 9.3% and 13.2% in mAP50 and mAP95, an 11.25% increase in frames per second, and a 69.85MB decrease in model size. …”
-
247
Effectiveness of Positron Emission Tomography for Predicting Chemotherapy Response in Colorectal Cancer Liver Metastases
Published 2010“…For example, a few years ago an extrahepatic metastasis effectively eliminated surgical resection, but a combination of chemotherapeutic options and surgical techniques has expanded the indications for resection and increased the population of patients who may benefit.1,2 Neoadjuvant chemotherapy has increased the resectability rate by 11% to 37%.1 Unfortunately, greater than 80% of patients undergoing hepatic resection will have recurrences, mostly within the first 2 years.2 Nonetheless, the only hope for cure is resection, and prior surgical dogma based on the number of lesions, size of the tumor-free resection margin, and presence of resectable extrahepatic disease must be questioned.3- 5 The current standard approach to surgical planning is contrast-enhanced computed tomography (CT) or magnetic resonance imaging (MRI) for specific tumor characteristics or contraindications to CT.6 Several series showed that focal extrahepatic disease, an isolated pulmonary lesion, can be safely resected, with 5-year survival rates of 29% to 58%.7,8 In 1 series,7 17 of 30 patients required 3 or more resections. …”
Get full text
Get full text
Get full text
article -
248
Spatial modelling of contribution of individual level risk factors for mortality from Middle East respiratory syndrome coronavirus in the Arabian Peninsula
Published 2017“…The odds of dying from the disease was found to increase as age increased beyond 25 years and was much higher for individuals with any underlying comorbidities.…”
-
249
Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans
Published 2024“…In addition to cell lines, we assessed the impact of BTZ in an in vivo setting using Caenorhabditis elegans (C. elegans). …”
-
250
Open access of evidence‐based publications
Published 2015“…We demonstrated that despite a 10‐fold increase in the number of evidence‐based publications in the past 10 years, the rate of free systematic reviews in the general biomedical literature did not change for the last two decades. …”
Get full text
Get full text
Get full text
Get full text
article -
251
Teaching the novel in a university english as a foreign language (EFL) context
Published 2016“…The aim of the present study is to explore the preliminary  effect of selected novels combined with film and student oral presentations on L1 Arabic EFL learners  use of vocabulary in one 20th Century American Novel course at an English medium university in Lebanon. Two literary essay tests were administered to 25 students, one at the beginning and another at the end of the semester, holistically scored and qualitatively analyzed for vocabulary variety. Main findings indicated that although the holistic scores did not significantly increase, there was use of a more diverse and use of vocabulary on Test 2. Recommendations are made for classroom practice and future research.…”
Get full text
Get full text
Get full text
article -
252
The Impact Of E-Leadership On Employees
Published 2023“…Work-from-home became an increasingly common business practice and company offices increasingly became unoccupied. …”
Get full text
Get full text
Get full text
masterThesis -
253
Modulation of Chronic Stress Outcomes by Dietary Sweeteners: A Comparative Study of Sucrose and Aspartame in Mice
Published 2025“…In contrast, aspartame did not appear to mitigate behavioral effects of stress. …”
Get full text
Get full text
Get full text
masterThesis -
254
Thermal Properties of TiO2NP/CNT/LDPE Hybrid Nanocomposite Films
Published 2018“…The TONP incorporation did not modify the Xc %. Moreover, thermal gravimetric analysis (TGA) thermograms confirmed the increased thermal stability after introducing CNTs and hybrid fillers compared to TONP incorporation.…”
-
255
Comparative Evaluation of Membrane Filtration on the Tertiary Treatment of Synthetic Secondary Effluent
Published 2022“…Moreover, as pressure increased there was a slight increase in the efficiency. …”
Get full text
article -
256
-
257
-
258
The distribution of toxic sources in Louisiana
Published 1993“…Furthermore, the greater the percentage of blacks in a community, the greater the reductions in discharges. …”
Get full text
Get full text
Get full text
masterThesis -
259
Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Kefir's anti‑cancer potential was tested on CRC cell lines, Caco‑2 and HT‑29, through cytotoxicity, proliferation, and apoptotic assays. …”
Get full text
Get full text
Get full text
article -
260
Risk Factors for Post-Cesarean, Surgical Site Infections in a Multi-Ethnic Population of Qatar
Published 2024“…In our hospital, the SSIs after CD were noted to increase in 2016 and first quarter of 2017. One of the methods implemented for SSI reduction included identifying modifiable risk factors.…”