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Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling
Published 2019“…Altogether our findings demonstrate that SNG induces mitochondrial and caspase-dependent apoptosis, generates oxidative stress, and suppresses MM cell lines proliferation. In addition, co-treatment of MM cell lines with sub-toxic doses of SNG and BTZ potentiated the cytotoxic activity. …”
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Greensporone A, a Fungal Secondary Metabolite Suppressed Constitutively Activated AKT via ROS Generation and Induced Apoptosis in Leukemic Cell Lines
Published 2019“…We studied the anticancer activity of greensporone A in a panel of leukemic cell lines. Greensporone A-mediated inhibition of proliferation is found to be associated with the induction of apoptotic cell death. …”
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Photoactivatable RuII Complex Bearing 2,9‐Diphenyl‐1,10‐phenanthroline: Unusual Photochemistry and Significant Potency on Cisplatin‐Resistant Cell Lines
Published 2018“…The current study investigates [Ru(bipy)2(dpphen)]Cl2 [where bipy = 2,2′‐bipyridine and dpphen = 2,9‐diphenyl‐1,10‐phenanthroline] (complex 1) for photoactivatable chemotherapy (PACT) application on five cancer cell lines. [Ru(bipy)2(phen)]Cl2 [where phen = 1,10‐phenanthroline] (complex 2) was included as an unstrained control. …”
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Money and credit policies in small open less-developed economies
Published 1986“…Some of our results were not in line with the analysis in the existing literature because of the differentiating characteristics of the financial markets in the study.…”
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Fluid Administration in Emergency Room Limited by Lung Ultrasound in Patients with Sepsis: Protocol for a Prospective Phase II Multicenter Randomized Controlled Trial
Published 2020“…Thus, B lines seen by bedside ultrasound may have a role in guiding fluid therapy.…”
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Multicast at Edge: An Edge Network Architecture for Service-Less Crowdsourced Live Video Multicast
Published 2021“…In this paper, we propose an overlay network architecture to augment eMBMS to address the limitations of the standard eMBMS architecture and enable service-less multicast for crowdsourced live video providers. …”
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Why and when do family firms invest less in talent management? The suppressor effect of risk aversion
Published 2021“…Risk-averse family-owned firms tend to invest less in talent management practices when industry competition is weak. …”
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A relational frame skills training intervention to increase general intelligence and scholastic aptitude
Published 2016“…In Experiment 1, fifteen 11–12 year old children were exposed over several months to an intensive training intervention to improve their understanding of the relations Same, Opposite and More and Less. Significant increases in full scale IQ of around one standard deviation were recorded for each child. …”
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Increasing methylation of sperm rDNA and other repetitive elements in the aging male mammalian germline
Published 2020“…Similar to the tandemly repeated rDNA, methylation of human α‐satellite and interspersed LINE1 repeats, marmoset α‐satellite, bovine alpha‐ and testis satellite I, mouse minor and major satellite, and LINE1‐T repeats increases in the aging male germline, probably related to their sperm histone packaging. …”
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Deep learning-based modeling of land use/land cover changes impact on land surface temperature in Greater Amman Municipality, Jordan (1980–2030)
Published 2024“…This study aimed to model past, present, and future LULCC on Land Surface Temperatures in the Greater Amman Municipality (GAM) in Jordan between 1980 and 2030. …”
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The Association of Hypertension with Increased Mortality Rate During the COVID-19 Pandemic: An Update with Meta-analysis
Published 2023“…Subgroup analyses indicated that patients with COVID-19 who have hypertension and male patients had slightly less risk of mortality than female patients [the percentage of men > 50%; OR 1.33: 95% CI (1.01, 1.76); the percentage of men ≤ 50%: OR 2.26; and 95% CI (1.15, 4.48)]. …”
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Cardiovascular autonomic neuropathy is associated with increased glycemic variability driven by hyperglycemia rather than hypoglycemia in patients with diabetes
Published 2023“…ConclusionCAN was associated with increased glycemic variability with less time in euglycemia attributed to a greater time in hyperglycemia but not hypoglycemia.…”
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Cardiovascular autonomic neuropathy is associated with increased glycemic variability driven by hyperglycemia rather than hypoglycemia in patients with diabetes
Published 2023“…</p><h3>Conclusion</h3><p dir="ltr">CAN was associated with increased glycemic variability with less time in euglycemia attributed to a greater time in hyperglycemia but not hypoglycemia.…”
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Assessment of tropospheric NO<sub>2</sub> concentrations over greater Doha using Sentinel-5 TROPOspheric monitoring instrument (TROPOMI) satellite data: Temporal analysis, 2018–202...
Published 2024“…<p dir="ltr">This study presents a temporal evaluation of the tropospheric NO<sub>2</sub> column densities over Greater Doha using TROPOMI satellite data from May 2018 to December 2023, and an assessment of the impact of the preparations and hosting of the FIFA Football World Cup Qatar 2022, on NO<sub>2</sub> levels before, during and after the tournament over Greater Doha. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…Methods and results Using the WST assay, the pentane fraction (F1) and 1:1 pentane:diethyl ether fraction (F2) were shown to possess the highest cytotoxicity against both cell lines. Flow cytometric analysis revealed that both fractions induced the accumulation of cells in the sub-G1 phase, increase in apoptotic cell death and chromatin condensation. …”
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The anti-cancer effect of the pentane fraction of Daucus carota oil extract is mediated through cell cycle arrest and an increase in apoptosis
Published 2013“…Previous studies from our laboratory demonstrated the in vitro anticancer activities of Daucus carota oil extract (DCOE) on colon and breast human cancer cell lines. In the current study, we aimed at fractionating the Daucus carota oil extract (DCOE) and analyzing the in vitro anticancer activities of the obtained fractions. …”
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