Protein arginine methyltransferase 5 (PRMT5) activates WNT/β‐catenin signalling in breast cancer cells via epigenetic silencing of DKK1 and DKK3 حسب Harshita Shailesh (14779408)

"…<p></p><div> <p>Protein arginine methyltransferase 5 (PRMT5) activity is dysregulated in many aggressive cancers and its enhanced levels are associated with increased tumour growth and survival. However, the role of PRMT5 in breast cancer remains underexplored. …"

Inositol 1,4,5-Trisphosphate Receptors in Hypertension حسب Ali H. Eid (5461829)

"…This involves a phenotypic switch of VSMCs as well as an alteration of cytoplasmic Ca²⁺ signaling machinery, a phenomena tightly related to the aging process. Several lines of evidence implicate changes in expression/function levels of IP₃R isoforms in the development of hypertension, VSMC phenotypic switch, and vascular aging. …"

Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway حسب Kirti.S. Prabhu (17191231)

"…SNG treatment increased Bax/Bcl-2 ratio, which contributed to a leaky mitochondrial membrane leading to cytochrome c release accompanied by caspase activation. …"

A possible culprit for refractory angina حسب Nature Research (16552612)

"…</p><p>This may implicate lipoprotein(a) as having a causal role in refractory angina, but the findings still need to be confirmed by testing a control group of patients who have coronary heart disease but not refractory angina.</p><p>An increased lipoprotein(a) level is known to be highly heritable, and is believed to promote hardening of the arteries by trapping cholesterol in the inner linings of blood vessels, promoting clot formation, recruiting inflammatory cells, or binding pro-inflammatory phospholipids.…"

Eating habits and obesity among Lebanese university students حسب Rizk, Sandra

"…Female students showed healthier eating habits compared to male students in terms of daily breakfast intake and meal frequency. 53.3% of female students reported eating breakfast daily or three to four times per week compared to 52.1% of male students. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

"Thrombosis takedown, safeguarding your journey": QI project to raise Venous Thromboembolism (VTE) awareness among staff and patients at Hamad International Airport, North Node Cli... حسب Muhammad Azhar Majeed (18506948)

"…Air travel carries a relative VTE risk 2.8 times higher than the general population risk of 1/1,000. …"

Knowledge and Anxiety about COVID-19 in the State of Qatar, and the Middle East and North Africa Region—A Cross Sectional Study حسب Sathyanarayanan Doraiswamy (4091776)

"…Panic and unfounded anxiety, as well as casual and carefree attitudes, can propel risk taking and mistake-making, thereby increasing vulnerability. It is important that governments, public health agencies, healthcare workers, and civil society organizations keep themselves updated regarding scientific developments and that they relay messages to the community in an honest, transparent, unbiased, and timely manner.…"

A Clinically Interpretable Approach for Early Detection of Autism Using Machine Learning With Explainable AI حسب Oishi Jyoti (21593819)

"…Early identification of ASD can significantly support timely intervention and treatment planning. While research in ASD diagnosis is evolving through the application of machine learning (ML) techniques, practical implementation in clinical settings has not progressed at the same pace. …"

A Financial Statement Analysis on Three Major Construction Companies in the UAE (Arabtec Holding PJSC, Drake & Scull PJSC and Emaar Properties PJSC) حسب AlEid, AlJazzy Bint Mohamed

"…Desirable liquidity ratio of (1.5-2 times) is a good indicator of a company’s position and the sample chosen companies are meeting the standards of the desirable liquidity ratio.  Leverage ratios have been studied to observe the debt dependency of the companies. …"
احصل على النص الكامل

Optimizing microgrid efficiency: Coordinating commercial and residential demand patterns with shared battery energy storage حسب Mohammadreza Gholami (17032317)

"…Moreover, considering DTR for transmission lines, instead of fixed thermal rating, improves the PAR and DPS up to 28.52 % and 41.06 % respectively. …"

Technical Aspects of Developing Chatbots for Medical Applications: Scoping Review حسب Zeineb Safi (18281719)

"…They provide patients with timely information that can be critical in some scenarios, such as access to mental health resources. …"

Neutrophil‐to‐lymphocyte ratio as a predictor of clinical outcomes in critically ill COVID‐19 patients: A retrospective observational study حسب Husain S. Ali (11659423)

"…<p></p><div> <h3> Background</h3> <p>Timely identification of patients at risk of worse clinical outcomes is vital in managing coronavirus disease 2019 (COVID-19). …"

A systematic review and meta-analysis on the impact of early vs. delayed pharmacological thromboprophylaxis in patients with traumatic brain injury حسب Muhammad Hamza Shuja (19748620)

"…Early PTP was categorized based on the timing of administration: 1) within 24 h, 2) within 48 h, and 3) within 72 h of hospital admission. …"

ACTB Loss-of-Function Mutations Result in a Pleiotropic Developmental Disorder حسب Sara Cuvertino (18892069)

"…<i>ACTB</i> mRNA expression levels in lymphoblastic lines and fibroblasts derived from affected individuals were decreased in comparison to those in control cells. …"

PDX1⁻/NKX6.1⁺ progenitors derived from human pluripotent stem cells as a novel source of insulin‐secreting cells حسب Bushra Memon (4792767)

"…Also, the 3D-beta cells secreted C-peptide in response to increased glucose concentrations indicating their functionality.…"

Fixed Shading Scenarios to Optimize Lighting Performance and Energy Efficiency in Office Buildings Case Study of Dubai Design District حسب Hamad, Khadije

"…The daylight analysis was conducted on one typical office space during three timings, 9:00 am, 12:30, and 17:00, on two dates, 21st of December and 21st of June, to check variations. …"
احصل على النص الكامل

Liver resection for liver metastases from nondigestive endocrine cancer حسب Andreou, Andreas

"…The number of extrahepatic sites of metastasis and the timing of appearance of liver metastases should be considered in patient selection. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The English Language Centre Community College Qatar: A Position Report حسب Irum Naz (17948078)

"…The idea of integrating skills was also put forth as a means of increasing the efficiency of the program and rendering it more cost effective. …"

Deletion of <i>RFX6</i> impairs iPSC-derived islet organoid development and survival, with no impact on PDX1⁺/NKX6.1⁺ progenitors حسب Noura Aldous (15429873)

"…Furthermore, induced pluripotent stem cell (iPSC) lines lacking RFX6 were generated using CRISPR/Cas9. …"