Characterization of the potency and mechanism of action of a novel dual-selective intermolecularly complemented version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Acute... حسب Farhat, Mirna

"…However, given that MMP9 was found not to be expressed in the sensitive cell lines, we were able to exclude its expression as a requirement for cytotoxicity. …"
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Human recombinant arginase I(Co)-PEG5000 [HuArgI(Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human acute myeloid leukemia cells حسب Bekdash, Amira

"…In this study, we target arginine auxotrophy of AML cell lines using human arginase I cobalt-PEG5000. HuArgI(Co)-PEG5000 was cytotoxic to all AML cell lines tested. …"
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The Anti-Tumor Effect of Flaxseed Lignan Derivatives on Different Acute Myeloid Leukemia Cancer Cells حسب Tannous, Stephanie

"…Cytotoxicity assays, using WST-1, revealed dose- and time- dependent effects in various AML cell lines with the most prominent cytotoxicity exhibited by ENL. …"
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The Impact of Sporting Events on Air Pollution: An Empirical Examination of National Football League Games حسب Nicholas Watanabe (19450285)

"…<h3>Background</h3><p dir="ltr">Prior research has found that large-scale sporting events may potentially impose negative consequences on the environment, thus impeding the sustainability goals of the sport industry. Along these lines, the current study extends the literature by examining the impact that National Football League (NFL) games have on local-area air pollution. (2) Methods: Air Quality Index (AQI) data measuring six major forms of air pollution were gathered from air monitors positioned close to NFL stadiums and matched with the number of attendees at games. …"

Impacts of On-Grid Solar PV on Distribution Networks and Potential Solutions: A Case Study in the Region of Zahle حسب Korkmaz, Jessica

"…For this purpose, the research develops a model for heavily PV DG-loaded distribution lines in Zahle. Then, power flow simulations are conducted in OpenDSS on these modeled lines with and without the presence of PV DGs to quantify their impacts on voltage, power factor, and power flows. …"
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Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro حسب Rizk, Sandra

"…The pro-apoptotic effect upon combination of topotecan with andrographolide was further observed using annexin V/PI staining; even though andrographolide alone did not alter cell survival, however, when applied to the cells prior to topotecan treatment, the number of apoptotic cells increased from 16% to 57%. Conclusion: Pretreating acute myeloid leukemia cell lines with non-cytotoxic doses of andrographolide promotes the anti-tumor effect of topotecan in vitro.…"
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Anti-cancer Evaluation of Lebanese Cannabis Oil Extract on Lung and Breast Cancer Cells حسب Saliba, Jane

"…In this study, we look at the anti-tumorigenic effects of Lebanese COE on non-small cell lung cancer cell line (NSCLC) A549 and the triple negative breast cancer cell line (MDA-MB-231). …"
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Targeting deregulated oxidative stress in skin inflammatory diseases: An update on clinical importance حسب Abdul Q. Khan (14153247)

"…However, research obtained over the last few decades has revolutionized the understanding of cutaneous disease pathogenesis and therapeutic developments. In this line, increasing data from pre-clinical and clinical studies implicates the crucial role of oxidative stress in pathogenesis and complications of cutaneous inflammatory diseases, including atopic dermatitis and psoriasis. …"

The Activation Kinetics and Crosstalk of RhoGTPases حسب Al Haddad, Maria

"…Using this technique, we are studying the crosstalk of Rho GTPases in different cell lines, with a focus on RhoA, RhoC, Cdc42 and Rac1. …"
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Effect of Construction Void Defects on Flexural and Axial Load Capacity of Reinforced Concrete Members حسب Al Moukdad, Mohammad Mustafa

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Investigation of positive education implementation and its impact on students' wellbeing and academic self-efficacy in K-12 private schools in Dubai حسب KHREIBI, RIMA ABOU

"…The findings revealed the following: 1) in recent years there has been increasing positive education implementation grounding in the recent international, national, local, and educational authority policies and initiatives. 2) absence of standardised local and school policy related to positive education implementation has led to the need for adaptability of positive education implementation across school. 3) there has been strong engagement of the internal school community (teachers, school leaders and students) with external school community (parents). 4) significant changes in the overall level DSWC indicators associated with social emotional wellbeing, life satisfaction, perseverance, feeling safe, and belonging to school. 5) insignificant changes associated with DSWC indicators associated with emotional regulation, happiness, optimism, academic self-concept, cognitive engagement, engagement (flow), peer belonging and school climate. 6) PASS assessment factors show increase in wellbeing, motivation and self-efficacy for regulation and decrease in academic self-efficacy. 7) significant increase in emotional, social wellbeing and academic self-efficacy among students due to positive education implementation as perceived by teachers, parents, and students.…"
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The effects of a change in the point system on immigration حسب Chemin, Matthieu

"…In line with the initial objective, we find more French-speaking immigrants with bachelor’s degrees, and no worsening in labor market outcomes after the reform. …"
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ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000] حسب Abdel Khalek, Maya

"…In this study, we examine the mechanism of HuArgI (Co)-PEG5000-induced cell death in both partially and completely auxotrophic GBM cell lines. Our results first showed a significant increase in HuArgI (Co)-PEG5000 treated cells for both U251 and A172 in autophagosome formation; suggesting activation of autophagy in response to arginine deprivation. …"
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The Extent to Which Schools with Mechanistic Structures and their Job Characteristics are Likely to Generate Teachers’ Organisational Commitment: Study Conducted in a Private Schoo... حسب Mansour, Hadi

"…Staff are motivated due to their perception of the importance of their roles however an increase in autonomy and authority in decision making as well as diversifying the job skills used during teaching could further increase motivation. …"
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Parallel multi-voltage power minimization in VLSI circuits. (c2013) حسب Younes, Rabih Halim

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Ultrasound‑triggered herceptin liposomes for breast cancer therapy حسب Elamir, Amal

"…Compared to the control liposomes, TRA-liposomes showed higher cellular toxicity and higher drug uptake by the HER2 + cell line (SKBR3) which was further improved following sonication with LFUS. …"
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Type 2 Diabetes Mellitus Automated Risk Detection Based on UAE National Health Survey Data: A Framework for the Construction and Optimization of Binary Classification Machine Learn... حسب Mohamed, AlShuweihi

"…ML based informal diagnostic and decision support systems can provide a first line of detection to alert patients about potential disease risk. …"
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Dexamethasone Promotes a Stem-Like Phenotype in Human Melanoma Cells <i>via</i> Tryptophan 2,3 Dioxygenase حسب Marta Cecchi (21363581)

"…Moreover, dex stimulates spherogenesis of both cell lines, which is mediated by TDO, evident by its suppression with 680C91, a TDO inhibitor. …"

Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic... حسب Muhanad Alhujaily (11630107)

"…Spliceosomal gene expression correlated positively with Glo1 in human tumor cell lines and tumors. In clinical chemotherapy of breast cancer, increased expression of Glo1 was associated with decreased patient survival, with hazard ratio (HR) = 1.82 (logrank p < 0.001, n = 683) where upper quartile survival of patients was decreased by 64% with high Glo1 expression.…"

The effect of daucus carota pentane-diethylether fraction on cancer cells motility and metastasis. (c2013) حسب Zgheib, Perla Z.

"…Upon treatment, a pronounced decrease in cancer cell motility was observed in the four cell lines used. The treatment also led to a decrease in cancer cell invasion and an increased cell adhesion. …"
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