Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes by Maryam Aghadi (17128819)

“…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …”

Effects of short term genotropin (rgGH) subcutaneous injection on active ghrelin concentration in rat plasma, stomach, kidney & pancreas. (c2007) by Haddad, Haytham

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Characterization of the Potency and Mechanism of Action of a Novel Dual-Selective Intermolecularly Complemented Version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Breas... by Basala, Sobhiya

“…Results show that UACC-2087 cell line expresses the three proteases and upon treatment, the levels of expression were not consistent. …”
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Cytotoxicity of Anthrax Lethal Toxin to Human Acute Myeloid Leukemia Cells Is Nonapoptotic and Dependent on Extracellular Signal-Regulated Kinase 1/2 Activity by Abi-Habib, Ralph J.

“…We tested potency of LeTx on a panel of 11 human AML cell lines. Seven cell lines showed cytotoxic responses to LeTx. …”
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Do high energy-efficient buildings increase overheating risk in cold climates? Causes and mitigation measures required under recent and future climates by Mutasim Baba, Fuad

“…While without adequate ventilation, the overheating risk in high-energy-efficient buildings can be higher than old buildings, where decreasing wall and window U-values and infiltration rate has a greater contribution to the increase of indoor temperature, while decreasing window SHGC has a lower contribution to the decrease in indoor temperature compared to the case with adequate ventilation. …”
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Identification of Cancer Stem Cells in Human Gastrointestinal Carcinoid and Neuroendocrine Tumors by Gaur, Puja

“…We sought to identify gastrointestinal neuroendocrine CSCs (N-CSCs) in surgical specimens and a NET cell line and to characterize novel N-CSC therapeutic targets. …”
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Renewable Energy Consumption and Carbon Emissions: Evidence from an Oil-Rich Economy by Shahriyar Mukhtarov (19325662)

“…The results reveal that renewable energy consumption has a negative impact on CO₂ emissions, while real GDP per capita has a positive effect. According to the findings, a 1% increase in renewable energy consumption leads to a 0.26% decrease in consumption-based CO₂ emissions, while a 1% rise in real GDP per capita leads to a 0.46% rise in consumption-based CO₂ emissions. …”

The impact of maternal care on child development by Sayour, Nagham

“…Results show that treated children enjoy an increase of 3.6 h per week in the time they spend with their mothers, mainly due to a decrease in the time spent in non-institutional care. …”
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Gaining or Losing Team Ball Possession: The Dynamics of Momentum Perception and Strategic Choice in Football Coaches by Walid Briki (688845)

“…Nonetheless, both variables displayed asymmetrical effects, in the sense that: (1) the strength of positive PM appeared to be easier to decrease than to increase; and (2) the greater the positive PM (or the negative PM), the lesser (or the greater) the coaches’ tendency to make a change in the organization of their teams. …”

Operation optimization of propane pre-cooled mixed refrigerant LNG Process: A novel integration of knowledge-based and constrained Bayesian optimization approaches by Roba Shady (22048043)

“…At large-scale LNG production (10,000 tons per day), the reduction in the SEC is translated into an 18 MW decrease in compression power, saving approximately 4.7 million $ per year for each C3MR train. …”

Effect of consanguinity on birth weight for gestational age in a developing country by Wakim, Gerard

“…No significant difference was observed in the decrease in birth weight between the first- and second-cousin marriages. …”
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Why do some countries produce more capital intensive output than others? by Toukan, Amjad

“…Our model predictions suggest that differences in productivity and therefore output per worker across countries are driven primarily by differences in the quality of governance. …”
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Antitumor activity of β-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways by Daaboul, Hamid E.

“…The SW1116 colon cancer cell line was treated with HC (1, 5, 10 and 25 μg/ml) and cell viability was evaluated with WST 1 assay kit. …”
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The mechanisms of resistance of anthrax lethal toxin (LeTx)-induced cytotoxicity in AML cells. (c2018) by Abou Harb, Monica

“…Our results indicate that vertical inhibition by SCH772984 rendered the resistant cell lines sensitive to the inhibition of the MAPK-pathway and showed an increased cytotoxic effect once used in combination with anthrax lethal toxin compared to the use of anthrax lethal toxin alone.…”
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The mechanism of action of kefir and its effect on the motility of breast and colorectal cancer cells. (c2013) by Khoury, Nathalie El

“…Western blot assay results confirmed the previously observed increase in apoptosis as it showed an increase in Bax:Bcl-2 expression upon kefir treatment. …”
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Comparative Effect of Sodium Butyrate and Sodium Propionate on Ovarian Cancer Migration, Invasion, and Epithelial-To-Mesenchymal Transition by Sleem, Reem

“…Methodology: The two ovarian cancer cell lines, SKOV-3 and PA-1, were treated with NaB and NaP for 24h. …”
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Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells by Al Sayyed, Fatima

“…In this study, we investigate the efficacy of two small molecules Ruxolitinib, a JAK/STAT inhibitor, and CHIR-99021, a GSK-3 inhibitor, in targeting pediatric neuroblastoma stem cells by testing them on human MYC-N amplified, IMR-32, and non-MYC-N amplified, SK-N-SH, cell lines. Treating neuroblastoma cells with Ruxolitinib and CHIR-99021 resulted in significant reduction in cellular proliferation, viability, apoptosis and tumorsphere formation capacity in both IMR-32 and SK-N-SH cell lines. …”
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Targeting potential arginine auxotrophy in glioblastoma (GBM) cells using human recombinant arginase I (CO)-PEG 5000 [HuArgl (Co)-PEG5000]. (c2013) by Khoury, Oula

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Reduction of laboratory utilization in the intensive care unit by Diab, Khalil

“…The number of iSTAT laboratory tests per patient-day decreased from 7.37 to an average of 1.16 (P < .001) over the same time period. …”
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Evapotranspiration and water availability response to climate change in the Middle East and North Africa by Salah Basem Ajjur (14150967)

“…Outcomes reveal that the MENA region is indeed vulnerable to a surge in temperature, which can increase evapotranspiration losses and decrease water availability. Under the shared socioeconomic pathway (SSP2-4.5), the potential evapotranspiration (PET) has been projected to increase throughout the MENA region by up to 0.37 mm per year during the middle of the twenty-first century (2021–2050) and by up to 0.51 mm per year during the end of the twenty-first century (2071–2100). …”