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Flavin Adenine Dinucleotide (FAD) and Pyridoxal 5′-Phosphate (PLP) Bind to Sox9 and Alter the Expression of Key Pancreatic Progenitor Transcription Factors
Published 2022“…Previously, there was no known link between FAD, PLP, or other co-factors and Sox9 for function. …”
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Anticancer activity of Neosetophomone B by targeting AKT/SKP2/MTH1 axis in leukemic cells
Published 2022“…<p>Neosetophomone B (NSP–B), a meroterpenoid fungal secondary metabolite, was investigated for its anticancer potential in leukemic cell lines (K562 and U937). NSP-B treatment of leukemic cells suppressed cell viability by triggering apoptotic cell death. …”
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203
Scalable Generation of Mesenchymal Stem Cells and Adipocytes from Human Pluripotent Stem Cells
Published 2020“…Disruption of cell adhesion induced the subsequent differentiation of the highly expanded RA-derived EB-forming cells into a pure population of multipotent MSCs (up to 1542-fold increase in comparison to RA-untreated counterparts). …”
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Investigating the Fluorescence Quenching of Doxorubicin in Folic Acid Solutions and Its Relation to Ligand-Targeted Nanocarriers
Published 2015“…The folate receptor is widely expressed on the surface of several cell lines and tumors; including ovarian, brain, kidney, breast, and lung cancers. …”
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205
Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018)
Published 2018“…Cytotoxicity of [HuArgI (Co)-PEG5000] was tested on two GBM cell lines, namely A172 and U251. Both cell lines showed increased sensitivity at longer incubation periods of [HuArgI (Co)-PEG5000] treatment with IC50 values in the pM range, a result attributable to the arginine auxotrophy expressed in those two cell lines. …”
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206
Evaluation of pretreatment and membrane configuration for pressure-retarded osmosis application to produced water from the petroleum industry
Published 2021“…PRO is typically considered with seawater/river water pairings however greater energy can be recovered from hypersaline solutions including produced water (PW) from the petroleum industry. …”
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207
Graphite and metal nitrate-infused HDPE composites for enhanced thermal performance in energy-efficient building envelopes
Published 2025“…Analysis such as Fourier Transform Infrared Spectroscopy (FTIR), X-ray Diffraction (XRD), Differential Scanning Calorimetry (DSC), Thermogravimetric Analysis (TGA), Scanning Electron Microscopy (SEM), and dielectric spectroscopy analyses further revealed extensive interaction between filler matrices, a decrease in phonon scattering, and a positive increase in crystallinity which led to the improved thermal performance.The TGA results showed that the composite exhibited greater thermal stability, and the residue mass after the decomposition process was 9%, indicating increased carbonization and structural integrity. …”
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Nox2 Activity Is Required in Obesity-Mediated Alteration of Bone Remodeling
Published 2018“…It is also well recognized that a high-fat diet (HFD) induces obesity, which negatively impacts bone remodeling. …”
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213
A urokinase-activated recombinant diphtheria toxin targeting the granulocyte-macrophage colony-stimulating factor receptor is selectively cytotoxic to human acute myeloid leukemia...
Published 2004“…The activity of this toxin was then tested on a larger group of 13 human AML cell lines; 5 of the 13 cell lines were sensitive to DTU2GMCSF. …”
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Phase transitions of nanoemulsions using ultrasound: Experimental observations
Published 2012“…Additionally, as the size of the emulsion droplet increased, the intensity required for bubble formation decreased. As expected, perfluorohexane emulsions require greater intensity to form cavitating bubbles than perfluoropentane emulsions.…”
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Observations on Food Consumption Behaviors During the COVID-19 Pandemic in Oman
Published 2022“…Indeed, the paper findings indicated (i) a shift to healthier diets, as shown by the fact that 45.5% of the participants increased their intake of fruits and vegetables, 42.4% ate more healthy foods, and 53.1% reduced their intake of unhealthy foods; (ii) an increase in the consumption of local products, owing to food safety concerns, with 25.8% of the cohort stating that they purchase more local food items; (iii) a shift in grocery shopping behaviors, especially with 28.1% of the participants buying more groceries online; (iv) the absence of panic buying in Oman, since 62.36% of the participants said they did not stockpile food items; and (v) a reduction of food waste. …”
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Disrupted harvests: how Ukraine – Russia war influences global food systems – a systematic review
Published 2024“…Effects on food utilization are mainly seen in the decrease in diet quality and dietary diversity. The war also affected the stability dimension, mainly owing to the volatility of food prices and the uncertainty of the future food supply. …”
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Characterization of the Potency and Mechanism of Action of a Novel Dual-Selective Intermolecularly Complemented Version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Breas...
Published 2023“…Results show that UACC-2087 cell line expresses the three proteases and upon treatment, the levels of expression were not consistent. …”
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220
Optimal IP network dimensioning for stream-type traffic using probabilistic delay constraints
Published 2006“…The CA problem is formulated as an optimization problem with nonlinear constraints, where the total link capacity shares allocated to the given service are minimized subject to performance constraints in terms of end-to-end delay requirements. …”
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