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Synergistic Effect of Epigenetic Inhibitors Decitabine and Suberoylanilide Hydroxamic Acid on Colorectal Cancer In vitro
Published 2019“…Objective: In this study, we evaluated the effect of Suberoylanilide Hydroxamic Acid (SAHA), a panhistone deacetylase inhibitor, and Decitabine (DAC), a DNA methyltransferase inhibitor, either alone or in combination, on Caco-2 human colon cancer cell line in vitro. Results: Our results showed that SAHA and DAC, separately, significantly decreased cell proliferation, induced apoptosis and cell cycle arrest of Caco-2 cell line. …”
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Rebound effects undermine carbon footprint reduction potential of autonomous electric vehicles
Published 2023“…<p dir="ltr">Autonomous vehicles offer greater passenger convenience and improved fuel efficiency. …”
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Curcumin Induces Apoptotic Cell Death via Inhibition of PI3-Kinase/AKT Pathway in B-Precursor Acute Lymphoblastic Leukemia
Published 2019“…Curcumin induces apoptosis in B-Pre-ALL cell lines via activation of caspase-8 and truncation of BID. …”
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165
Water-pipe smoking promotes epithelial–mesenchymal transition and invasion of human breast cancer cells via ERK1/ERK2 pathways
Published 2018“…Two breast cancer cell lines, MCF7 and BT20, were used in this investigation. …”
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166
Developing a Hybrid Model for Network Planning in Abu Dhabi Distribution Company Subsidiary of Adwea
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167
Effect of nickel loading on hydrogen production and chemical oxygen demand (COD) destruction from glucose oxidation and gasification in supercritical water
Published 2010“…Results also showed that the presence of Ni increased the total gas yield increased in the 7.5–18 wt Ni/Al2O3 catalyst. …”
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PSA-activated proaerolysin as a prostate specific cancer therapy
Published 2006“…The goal of this study was to examine the suitability of PRX302 for use as a therapeutic agent in prostate cancer and benign prostatic hyperplasia as assessed by comparing proteolytic activation of PRX302 and native proaerolysin and their cytotoxicity towards PSA-producing and non-producing cell lines. Modification of native proaerolysin to PRX302 markedly altered the activity of each of the proteases (chymotrypsin, trypsin, furin, and thrombin) tested toward this protein. …”
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169
Deep Learning-Based Fault Diagnosis of Photovoltaic Systems: A Comprehensive Review and Enhancement Prospects
Published 2021“…These faults may affect the different system components such as PV modules, connection lines, converters/inverters, which can lead to a decrease in the efficiency, performance, and further system collapse. …”
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170
Snake venom in conjugation with silica nanoparticles: an emerging cancer therapy
Published 2025“…<i>In vitro</i> investigations on cancer cell lines revealed a considerable increase in cytotoxicity and induction of apoptosis as compared to free snake venom, with greater selectivity for malignant cells. …”
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171
Sustainable Financing for Sustainable Development: Agent-Based Modeling of Alternative Financing Models for Clean Energy Investments
Published 2019“…This substantial amount of borrowing makes a negative contribution to the high global debt concentration, putting countries’ economic and social development at risk. In line with this, excessive debt-based financing causes an increase in wealth inequality, and when wealth inequality reaches a dramatic level, wars and many other social problems are triggered to correct the course of wealth inequality. …”
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172
Integrated Demand Side Management in Network Planning for Utility Companies
Published 2006Get full text
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173
Phospho-MEK1/2 and uPAR Expression Determine Sensitivity of AML Blasts to a Urokinase-Activated Anthrax Lethal Toxin (PrAgU2/LF) 1
Published 2015“…In this study, we attempt to target both the urokinase plasminogen activator and the mitogen-activated protein kinase pathway in acute myeloid leukemia (AML) cell lines and primary AML blasts using PrAgU2/LF, a urokinase-activated anthrax lethal toxin. …”
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Loss of the TRPM4 channel in humans causes immune dysregulation with defective monocyte migration
Published 2024“…<h3>Background</h3><p dir="ltr"><u>TRPM4</u> is a broadly expressed, calcium-activated, <u>monovalent</u> cation channel that regulates <u>immune cell</u> function in mice and cell lines. Clinically, however, partial loss- or gain-of-function mutations in <i><u>TRPM4</u></i> lead to <u>arrhythmia </u>and<u> heart disease</u>, with no documentation of<u> immunologic disorders.…”
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175
Free-space-optical communications over turbulent channels. (c2009)
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176
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Consumers’ health-locus-of-control and social distancing in pandemic-based e-tailing services
Published 2021“…In turn, consumers’ online grocery shopping behavior was found to increase during the pandemic, with their corresponding intent to continue this behavior in the future. …”
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178
Rapid simulation of building physical processes using the coarse-grain method
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179
Science Teachers’ Pedagogical Content Knowledge of Plastic Waste
Published 2022“…Plastic waste, with its links to science, politics, ethics and economics, can be classified as an SSI. …”
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180
Evaluation of pretreatment and membrane configuration for pressure-retarded osmosis application to produced water from the petroleum industry
Published 2021“…PRO is typically considered with seawater/river water pairings however greater energy can be recovered from hypersaline solutions including produced water (PW) from the petroleum industry. …”
