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881
Synergistic Effect of Epigenetic Inhibitors Decitabine and Suberoylanilide Hydroxamic Acid on Colorectal Cancer In vitro
منشور في 2019"…Objective: In this study, we evaluated the effect of Suberoylanilide Hydroxamic Acid (SAHA), a panhistone deacetylase inhibitor, and Decitabine (DAC), a DNA methyltransferase inhibitor, either alone or in combination, on Caco-2 human colon cancer cell line in vitro. Results: Our results showed that SAHA and DAC, separately, significantly decreased cell proliferation, induced apoptosis and cell cycle arrest of Caco-2 cell line. …"
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article -
882
'Ashura in Sydney
منشور في 2002"…Along with its highly dramatic content, 'Ashura in Sydney is transformed into a practice where the ethnic identity of Shi'i migrants is reproduced and at the same time modified to come to terms with the conditions of living in a new urban environment. In an increasingly globalised world, local and global factors are appropriated in the very process of celebrating 'Ashura and producing the Shi'i identity.…"
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article -
883
Impact of abiraterone on patient-related outcomes in metastatic castration-resistant prostate cancer
منشور في 2017"…Abiraterone acetate has established a major role in the treatment paradigm of metastatic castration-resistant prostate cancer ever since pivotal trials, COU-AA-301 and COU-AA-302, have shown benefit in both the second-line and first-line (post- and pre-chemotherapy) setting, respectively, with improvement in overall survival as well as secondary end points such as prostate-specific antigen (PSA) and radiographic response rates, time to PSA progression, and progression-free survival. …"
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article -
884
Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
منشور في 2024"…Additionally, the distribution of livebirths across the globe is shifting, with a greater proportion occurring in the lowest-income countries. …"
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article -
885
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886
Squamous Cell Carcinomas of the Head and Neck Cancer Response to Programmed Cell Death Protein-1 Targeting and Differential Expression of Immunological Markers: A Case Report
منشور في 2018"…His NY-ESO-1 antibody was found to be lower after the third (****p < 0.0001) and the fifth (****p < 0.0001) cycles of treatment compared to base line, and this was in line with the stability of the disease. …"
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887
Implementation of trust region methods in optimization. (c1998)
منشور في 1998احصل على النص الكامل
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masterThesis -
888
Exploring differences in work values among multigenerational workforce: Leadership approaches in selected higher educational institutions in the UAE
منشور في 2017"…A similar picture was observed when comparing Generation X-ers with Baby Boomers: salary raise (M=2.99 and M=3.28, p=0.00), pay increases to balance cost of living (M=2.99 and M=3.41, p=0.00) and being paid well (M=2.98 and M=3.41, p=0.00). …"
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889
The changing landscape in the treatment of metastatic castration-resistant prostate cancer
منشور في 2012"…The past few years have brought increasing advances in the therapeutic management of metastatic castration-resistant prostate cancer with the approval of several agents, including vaccine therapy with sipuleucel-T, second-line chemotherapy with cabazitaxel, the bone-targeted pharmaceutical denosumab, and the novel antiandrogen therapy abiraterone acetate. …"
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article -
890
The Effect of HuArgI (Co)-PEG5000 on The Migration of Ovarian Cancer
منشور في 2020"…Finally, we looked at the effect of HuArgI (Co)-PEG5000 on 3D motility of the ovarian cancer cell line, using a collagen based assay. It showed that SKOV3 cell line does not show significant invasiveness to collagen. …"
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masterThesis -
891
Emerging therapies in multiple myeloma
منشور في 2015"…However, despite the increased effectiveness of the first-line agents, the majority of patients will eventually relapse and become drug resistant. …"
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article -
892
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893
Gender and care
منشور في 2009"…By the end of 2007, there was an estimated 380,000 people living with HIV/AIDS in the region (WHO/UNAIDS/UNICEF, 2008). …"
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article -
894
Emerging Glycation-Based Therapeutics—Glyoxalase 1 Inducers and Glyoxalase 1 Inhibitors
منشور في 2022"…In the National Cancer Institute human tumor cell line screen, BBGD was most active against the glioblastoma SNB-19 cell line. …"
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895
PRAME promotes epithelial-to-mesenchymal transition in triple negative breast cancer
منشور في 2019"…Gene ontology analyses revealed enrichment of genes that are dysregulated in ovarian and esophageal cancer and are involved in transcription and apoptosis. In line with this, interrogation of TCGA and GTEx data demonstrated an increased PRAME expression in ovarian and esophageal tumor tissues in addition to breast tumors where it is associated with worse survival. …"
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896
Modeling and Performance Analysis of mmWave and WiFi-Based Vehicle Communications
منشور في 2024"…This study explores a comparative analysis of mmWave and WiFi transmission technologies, with a specific focus on line-of-sight (LoS) and non-line-of-sight (NLoS) scenarios in both 2D and 3D modeling environments. …"
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897
3D FEM Model on the Parameters’ Influence of EPB-TBM on Settlements of Single and Twin Metro Tunnels During Construction
منشور في 2022"…<p>The present research exposes the investigation on three-dimensional modeling of the single and twin metro tunnels for the case of the Tehran metro line. At first, simulation implemented on the comparison of the ground movements in the single and twin tunnels. …"
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898
Lyapunov-Function-Based Controller for Single-Phase NPC Quasi-Z-Source Inverter with 2<em>ω</em> Frequency Ripple Suppression
منشور في 2020"…Furthermore, the modified simple boost control technique is proposed to eliminate the double-line frequency ripples in the quasi-impedance source inductor currents and minimize the double-line frequency ripples in the quasi-impedance source capacitor voltages. …"
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899
The history and development of newspaper electronic pagination systems in the United States, 1975-1987
منشور في 1990"…This was perhaps, due to the unevenness with which the total pagination process has developed, and the continuing problems involved in merging line-art and graphics with text. Increased computer storage space and other advances may solve this problem soon, and satellite transmission of graphic art for national advertisements, to specific newspapers is a new development being planned for the near future.…"
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masterThesis -
900
Marketing communications
منشور في 2010"…Sponsorship has become increasingly popular - within companies that operate in consumer markets. …"
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article