Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015) حسب Azar, Daniel Fadi

"…Furthermore, we have attempted to examine the photochemical potential of our metal-organic compound model by combining L-II and L-III in the same metal complex, thus generating four final complexes with differing net charges (from +2 to -4), and examining their activities on a panel of AML cell lines with or without exposure to blue light. Of the four final complexes Ru-II3, Ru-II2-III, Ru-II-III2 and Ru-III3, only Ru-II3 and Ru-II2-III have shown significant activity against all tested cell lines in the dark, whereas photo-activation against ML2 has shown a marked increase of potency of all four complexes, even those shown to be biologically inert in the dark, reaching IC50 values in the nM range. …"
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Wild carrot oil extract is selectively cytotoxic to human acute myeloid leukemia cells حسب Tawil, Mirna

"…In this study, we used Daucus carota oil extract (DCOE) to target acute myeloid leukemia (AML) cells. All the AML cell lines tested were sensitive to the extract while peripheral mononuclear cells were not. …"
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Diffusion tensor imaging with tractography in surgical resection of brainstem cavernous malformations: a systematic review and meta-analysis حسب Mohammed Maan Al-Salihi (13105835)

"…About 12.4% of patients achieved partial resection, 65.65% improved, 8.07% worsened, 25.04% showed no change, 3.59% experienced postoperative re-bleeding, and 0.87% died. The utilization of preoperative diffusion tensor imaging significantly increased the proportion of improved patients and decreased the proportion of worsened patients. …"

Characterization of the potency and mechanism of action of a novel dual-selective intermolecularly complemented version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Acute... حسب Farhat, Mirna

"…However, given that MMP9 was found not to be expressed in the sensitive cell lines, we were able to exclude its expression as a requirement for cytotoxicity. …"
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Exam scheduling algorithms. (c1999) حسب Mikati, Ziad

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The Gulf Cooperation Council states: Crystallization of the regional cooperation and alliances amid dwindling resources حسب Evren Tok (14779270)

"…<p dir="ltr">The Gulf Cooperation Council (GCC) states can be divided into two main camps in terms of hydrocarbon endowment per capita which can partially account for differences in policy directions. …"

Editorial of Harnessing the Power of T Cells: The Promising Hope for a Universal Influenza Vaccine حسب Salman M. Toor (8854751)

"…<p dir="ltr">The global burden of influenza-associated respiratory mortality is higher than previous estimates, with over 0.6 million deaths per year and additional mortality rates attributed to non-respiratory but influenza-related illnesses [1]. …"

Research on the potential of photovoltaic technologies in reducing energy consumption in an urban mixed use residential community. A Case study for net zero energy community in Dub... حسب SUGATHAN, SANAL

"…This is mainly because most of its domestic energy needs are meet by subsidized electricity tariffs in Abu Dhabi also to blame for their high per capita GHG emissions. …"
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Drone Based Outdoor Insulator Inspection حسب Waleed, Danial

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Impacts of On-Grid Solar PV on Distribution Networks and Potential Solutions: A Case Study in the Region of Zahle حسب Korkmaz, Jessica

"…Recent years have witnessed an increase in the installation of solar photovoltaic-based distributed generators or PV DGs mainly in countries with high solar potential such as Lebanon. …"
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Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro حسب Rizk, Sandra

"…The pro-apoptotic effect upon combination of topotecan with andrographolide was further observed using annexin V/PI staining; even though andrographolide alone did not alter cell survival, however, when applied to the cells prior to topotecan treatment, the number of apoptotic cells increased from 16% to 57%. Conclusion: Pretreating acute myeloid leukemia cell lines with non-cytotoxic doses of andrographolide promotes the anti-tumor effect of topotecan in vitro.…"
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BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells حسب Ali Alhoshani (3720718)

"…However, the mechanisms of anti-cancer effect of VCX either as a monotherapy or in combination with other chemotherapeutic agents against breast cancer need investigation.</p><h3>Methods</h3><p dir="ltr">Breast cancer cell lines with different molecular subtypes (MDA-MB-231, MCF7, and SKBR-3) were treated with different concentrations of VCX for indicated time points. …"

Global, regional, and national burden of upper respiratory infections and otitis media, 1990–2021: a systematic analysis from the Global Burden of Disease Study 2021 حسب Sirota, Sarah Brooke

"…The mortality rate of URIs in 2021 was 0·2 per 100 000 (0·1 to 0·5), a decrease of 64·2% (–84·6 to –43·4) from 1990, when the mortality rate was 0·7 per 100 000 (0·2 to 1·1). …"
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Human recombinant arginase I(Co)-PEG5000 [HuArgI(Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human acute myeloid leukemia cells حسب Bekdash, Amira

"…In this study, we target arginine auxotrophy of AML cell lines using human arginase I cobalt-PEG5000. HuArgI(Co)-PEG5000 was cytotoxic to all AML cell lines tested. …"
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Fixed Shading Scenarios to Optimize Lighting Performance and Energy Efficiency in Office Buildings Case Study of Dubai Design District حسب Hamad, Khadije

"…The annual energy consumption of the optimal scenario is reduced from 1670 MWh to 1532MWh in the Egg-crate scenario three, which is a high reduction of 138MWh per year. Moreover, daylighting analysis shows decreased average illuminance levels from 407.8 to 154.97 Lux, equivalent to a 60% reduction in December and June. …"
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Efficacy of Antimicrobial-Impregnated Catheters in Preventing Sepsis Post Peripherally Inserted Central Venous Catheter (PICC) Removal in Neonates: A Retrospective Study حسب Mohammad Ayman Al Khateeb (17045509)

"…Further studies with a larger sample size are needed to confirm these results.</p>…"

Catalytic Transformation Of C-7-C9 Methyl Benzenes Over USY-Based FCC Zeolite Catalyst حسب Al-Khattaf, S

"…The sequence of reactivity of the three alkyl benzenes was found to decrease as the number of methyl group per benzene ring decreases, as follows: 1,2,4-trimethylbenzene > m-xylene > toluene. …"
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Solar water heating in Lebanon حسب Houri, Ahmad

"…Simplified initial estimates indicate a payback period of 4–5 years while advanced mathematical models (RETScreen) indicate that the most advanced evacuated tube technology has a payback period of less than 9 years at current market prices. With decreasing cost per square meter of installed collectors, payback periods are expected to rapidly decrease. …"
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ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000] حسب Abdel Khalek, Maya

"…In this study, we examine the mechanism of HuArgI (Co)-PEG5000-induced cell death in both partially and completely auxotrophic GBM cell lines. Our results first showed a significant increase in HuArgI (Co)-PEG5000 treated cells for both U251 and A172 in autophagosome formation; suggesting activation of autophagy in response to arginine deprivation. …"
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Assessing the Electricity Production Capacities of Emerging Markets for the Sustainable Investments حسب Tamer Aksoy (17947802)

"…For countries to have energy independence, they need to increase their electricity generation capacity. …"