-
181
Comparative Study on Beneficial Effects of Hydroxytyrosol- and Oleuropein-Rich Olive Leaf Extracts on High-Fat Diet-Induced Lipid Metabolism Disturbance and Liver Injury in Rats
منشور في 2020"…Equally, it showed a rise of the apoptotic markers (a decrease in the expression of the Bcl-2 and an increase of the P53). …"
-
182
Cost-Benefit Analysis of Antimicrobial Stewardship Program in the Adult General Medicine Setting in Qatar
منشور في 2024"…</p><h3> Results</h3><p dir="ltr">The operational costs of the program decreased with maturity by cost savings of QAR125 per 100-patient beds per year. …"
-
183
Phospho-MEK1/2 and uPAR Expression Determine Sensitivity of AML Blasts to a Urokinase-Activated Anthrax Lethal Toxin (PrAgU2/LF) 1
منشور في 2015"…PrAgU2/LF was cytotoxic to five out of nine AML cell lines. Cytotoxicity of PrAgU2/LF appeared to be nonapoptotic and was associated with MAPK activation and urokinase activity because all the PrAgU2/LF-sensitive cell lines showed both uPAR expression and high levels of MEK1/2 phosphorylation. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
article -
184
Global, regional and national burden of bladder cancer and its attributable risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of...
منشور في 2021"…Age-standardised death rate decreased by 15.7% (8.6 to 21.0), during the period 1990–2019. …"
-
185
Unsustainability in emergent systems
منشور في 2017"…In this paper we present a detailed case study of the passenger road transport system in the Greater Beirut Area (GBA) where we identify the root causes of the major problems facing the system today and over the long-term. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
conferenceObject -
186
Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways
منشور في 2015"…Flow cytometric analysis indicated that both fractions induced sub-G1 phase accumulation and increased apoptotic cell death. Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
article -
187
Enhanced cellular uptake and photochemotherapeutic potential of a lipophilic strained Ru(II) polypyridyl complex
منشور في 2019"…When compared to cisplatin, the photoproducts were more potent against all tested cell lines, implying that the complex acquired significant chemotherapeutic potential upon irradiation. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
article -
188
Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance
منشور في 2022"…<p>Early-stage detection of leukemia is a critical determinant for successful treatment of the disease and can increase the survival rate of leukemia patients. The factors limiting the current screening approaches to leukemia include low sensitivity and specificity, high costs, and a low participation rate. …"
-
189
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
منشور في 2019"…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …"
-
190
Hydrophobic Ionic Liquids for Efficient Extraction of Oil from Produced Water
منشور في 2022"…The extraction efficiency was found to increase with increasing cation alkyl chain length from C2 to C10. …"
احصل على النص الكامل
article -
191
Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres
منشور في 2024"…Cytotoxicity assays on human cell lines showed no toxicity towards cells at concentrations of up to 100 µg ml−1 but exhibited increased toxicity at concentrations exceeding 1000 µg ml−1. …"
احصل على النص الكامل
article -
192
Unraveling the future productivity burden of cardiovascular disease in Qatar: Investigating the modifiable risk factors control in type 2 diabetes
منشور في 2025"…The financial value of PALYs was determined based on the gross domestic product (GDP) per full-time worker (i.e. US$80,573). The base-case model estimated the productivity burden of CVD, and interventional scenarios were simulated to assess potential gains resulting from improved control of modifiable risk factors, including reduced incidence of T2D, lower systolic blood pressure (SBP), decreased number of smokers, and reduced total cholesterol. …"
-
193
YOLO-DefXpert: An Advanced Defect Detection on PCB Surfaces Using Improved YOLOv11 Algorithm
منشور في 2025"…Compared to the standard YOLOv11 model, the proposed YOLO-DefXpert attained an improvement of 9.3% and 13.2% in mAP50 and mAP95, an 11.25% increase in frames per second, and a 69.85MB decrease in model size. …"
-
194
Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans
منشور في 2024"…In addition to cell lines, we assessed the impact of BTZ in an in vivo setting using Caenorhabditis elegans (C. elegans). …"
-
195
The distribution of toxic sources in Louisiana
منشور في 1993"…Furthermore, the greater the percentage of blacks in a community, the greater the reductions in discharges. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
masterThesis -
196
Performance analysis of a new PV array reconfiguration approach: Simulations and outdoor experiments under fixed and moving shadows
منشور في 2025"…This paper introduces a new reconfiguration technique based on the Asterisk Sudoku strategy, designed to enhance energy yield in Total-Cross-Tied (TCT) PV arrays with minimal physical intervention. …"
-
197
Air pollution in Gaza during the post-october 7 era: a satellite and machine learning assessment
منشور في 2025"…SO<sub>2</sub> displayed episodic spikes, likely tied to fuel depot destruction and generator use, whereas NO<sub>2</sub> trends showed temporary suppression due to mobility restrictions and reduced industrial activity. …"
-
198
-
199
Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
منشور في 2014"…Kefir's anti‑cancer potential was tested on CRC cell lines, Caco‑2 and HT‑29, through cytotoxicity, proliferation, and apoptotic assays. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
article -
200
Investigating the Therapeutic Effects of Small Molecule Imipridones In Pediatric Neuroblastoma
منشور في 2020"…MYCN expression was significantly abrogated in the IMR-32 cell line with either drug treatment. The protein expression of Sox-2, Oct-4, FABP5 and HMGA1 was significantly reduced whereas cleaved PARP1 and caspase-3 and p-H2AX was increased 48 h after drug treatment in the MYCN-amplified IMR-32 cell line. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
masterThesis