A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate by Geethakumari, Anupriya M

“…Gaussian accelerated molecular dynamics (GaMD) simulations of the predicted alpha-helical synthetic Mpro cleavage sequences revealed a dynamic nature of the cleavage sequences, which is critical for their efficient cleavage, and a relatively short end-to-end distances, which is required for high BRET. Live cell assays revealed a cleavage sequence length-dependent resonance energy transfer, except for the 12× -syn cleavage site, and an increased rate of cleavage and a decreased pharmacological inhibitor efficacy for the Mpro biosensor containing 2× cleavage sequences. …”
Get full text
Get full text
Get full text

Performance analysis of power line communication systems with diversity combining under correlated lognormal fading and Nakagami noise by Abou-Rjeily, Chadi

“…In this study, the authors evaluate the bit error rate (BER) performance of multichannel power line communication (PLC) systems under lognormal fading and Nakagami-m background noise. …”
Get full text
Get full text
Get full text
Get full text

Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells by Shebaby, Wassim N.

“…Methods and results Using the WST assay, the pentane fraction (F1) and 1:1 pentane:diethyl ether fraction (F2) were shown to possess the highest cytotoxicity against both cell lines. Flow cytometric analysis revealed that both fractions induced the accumulation of cells in the sub-G1 phase, increase in apoptotic cell death and chromatin condensation. …”
Get full text
Get full text
Get full text

The anti-cancer effect of the pentane fraction of Daucus carota oil extract is mediated through cell cycle arrest and an increase in apoptosis by Mroueh, MA

“…Previous studies from our laboratory demonstrated the in vitro anticancer activities of Daucus carota oil extract (DCOE) on colon and breast human cancer cell lines. In the current study, we aimed at fractionating the Daucus carota oil extract (DCOE) and analyzing the in vitro anticancer activities of the obtained fractions. …”
Get full text
Get full text
Get full text
Get full text

Dextran Sodium Sulfate-Induced Impairment of Protein Trafficking and Alterations in Membrane Composition in Intestinal Caco-2 Cell Line by Toutounji, Mohamad

Get full text
Get full text
Get full text
Get full text

Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling by Sabah Akhtar (5809925)

“…Altogether our findings demonstrate that SNG induces mitochondrial and caspase-dependent apoptosis, generates oxidative stress, and suppresses MM cell lines proliferation. In addition, co-treatment of MM cell lines with sub-toxic doses of SNG and BTZ potentiated the cytotoxic activity. …”

Novel Platinum II and Platinum IV Complexes Exhibit An Anti-Neoplastic Potential Against A549 Cancer Cell Line by Baz, Joy

Get full text
Get full text
Get full text

Experimental Investigation of FRP-Reinforced Concrete Columns Under Concentric and Eccentric Loading by Elmesalami, Nouran Zinelabdin Ahmed

Get full text

Evaluation of Microplastics in Beach Sediments along the Coast of Dubai, U.A.E by Aslam, Huda

Get full text

Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019 by Jonathan M. Kocarnik (7512677)

“…The proportion of years lived with disability that contributed to DALYs increased with SDI, ranging from 1.4% (1.1%-1.8%) in the low SDI quintile to 5.7% (4.2%-7.1%) in the high SDI quintile. …”

Three-way decision-based conditional probabilities by opinion scores and Bayesian rules in circular-Pythagorean fuzzy sets for developing sustainable smart living framework by A. Alsattar, Hassan

“…Sustainable smart living (SSL) is a crucial component in the emergence of smart cities. …”
Get full text
Get full text

Greensporone A, a Fungal Secondary Metabolite Suppressed Constitutively Activated AKT via ROS Generation and Induced Apoptosis in Leukemic Cell Lines by Kirti Prabhu (3520064)

“…We studied the anticancer activity of greensporone A in a panel of leukemic cell lines. Greensporone A-mediated inhibition of proliferation is found to be associated with the induction of apoptotic cell death. …”

Photoactivatable RuII Complex Bearing 2,9‐Diphenyl‐1,10‐phenanthroline: Unusual Photochemistry and Significant Potency on Cisplatin‐Resistant Cell Lines by Mansour, Najwa

“…In conclusion, the Ru‐centered complex 1 could represent a potential photoactivatable chemotherapeutic drug that increases selectivity to tumors and offers alternative treatment in the light of increasing cisplatin resistance.…”
Get full text
Get full text
Get full text
Get full text

Effect of Girder Damage on the Structural Behavior of Slab-on-Girder Bridges by Elozn, Ahmed E.

Get full text

Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019 by Razieh, Hassannejad

“…FindingsIn contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. …”
Get full text
Get full text
Get full text

Living Materials: Preserving Student Innovation in Art and Science through Digital Twins and AI in Partnership with Qatar National Library : What Happens To Your Work After You Gra... by Arif Shaon (13761784)

“…The presentation also situates student work within a broader global research ecosystem, emphasizing citability, verification, and long-term impact in an era increasingly shaped by AI-generated content.</p><p dir="ltr">This resource is intended for students, educators, librarians, and institutions interested in sustainable models for preserving student innovation, practice-led research, and interdisciplinary creative outputs.…”

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 co... by Alize J, Ferrari

“…However, despite this overall increase, HALE decreased by 2·2% (1·6–2·9) between 2019 and 2021. …”
Get full text
Get full text
Get full text

Wastewater reuse for livestock feed irrigation as a sustainable practice: A socio-environmental-economic review by Fatima-Zahra Lahlou (16931766)

Performance evaluation of various growing media in vertical green wall for greywater treatment in hyper-arid climate by Jasir Jawad (17191468)

Violent Extremism Prevention in the Era of Globalization by Safieddine, Line Abbas

Get full text
Get full text
Get full text