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181
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182
Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro
منشور في 2016"…The pro-apoptotic effect upon combination of topotecan with andrographolide was further observed using annexin V/PI staining; even though andrographolide alone did not alter cell survival, however, when applied to the cells prior to topotecan treatment, the number of apoptotic cells increased from 16% to 57%. …"
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183
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184
Dual Targeting of Matrix Metalloproteases and the MAPK Pathway in Acute Myeloid Leukemia Cells Using an MMP-activated anthrax lethal toxin (PrAgL1/LF)
منشور في 2020"…Inhibition of the MAPK pathway through PrAgL1/LF led to sustained activation of autophagy, starting at 24 hours and lasting up to 120 hours following treatment with PrAgL1/LF in the AML cell lines. Addition of CQ led to an increase in cell cytotoxicity following treatment with PrAgL1/LF, at all time points, indicating that the inhibition of the MAPK pathway in AML cells leads to the activation of autophagy, which in turn mediates cell death following treatment with PrAgL1/LF. …"
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masterThesis -
185
Kefir induces cell-cycle arrest and apoptosis in HTLV-1-negative malignant T-lymphocytes
منشور في 2011"…However, kefir did not affect the mRNA expression of metalloproteinases needed for the invasion of leukemic cell lines. …"
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186
Malva pseudolavatera Leaf Extract Promotes ROS Induction Leading to Apoptosis in Acute Myeloid Leukemia Cells in Vitro
منشور في 2020"…Treatment of AML cell lines with M. pseudolavatera methanolic leaf extract showed a dose- and time-dependent inhibition of proliferation and a dose-dependent increase in apoptotic hallmarks such as an increase in phosphatidylserine on the outer membrane leaflet and membrane leakage in addition to DNA fragmentation. …"
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masterThesis -
187
Cytotoxicity of Anthrax Lethal Toxin to Human Acute Myeloid Leukemia Cells Is Nonapoptotic and Dependent on Extracellular Signal-Regulated Kinase 1/2 Activity
منشور في 2013"…Co-treatment of AML cells with both LeTx and LY294002 did not lead to increased sensitivity, showing a lack of additive/synergistic effects when both pathways are inhibited. …"
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article -
188
"Development of Authentic Annual and Seasonal Lightning Thunderstorms Day Maps for Saudi Arabia"
منشور في 2006"…The southern region in general, and especially the cities of Abha, Taif and Al-Baha, has shown greater numbers of thunderstorm days all year round. …"
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189
"Thunderstorm distribution and frequency in Saudi Arabia"
منشور في 2005"…The southern region in general, and especially the cities of Abha, Taif and Al-Baha, has shown greater numbers of thunderstorm days all year round. …"
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190
Annona cherimola Seed Extract Activates Extrinsic and Intrinsic Apoptotic Pathways in Leukemic Cells
منشور في 2019"…Treatment with an A. cherimola seed ethanolic extract promotes a dose- and time-dependent inhibition of the proliferation of various AML cell lines, but not MSCs. …"
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article -
191
Annona cherimola Seed Extract Activates Extrinsic and Intrinsic Apoptotic Pathways in Leukemic Cells By Peter Nasr A thesis
منشور في 2020"…Treatment with an A. cherimola seed ethanolic extract promotes a dose- and time-dependent inhibition of the proliferation of various AML cell lines, but not MSCs. …"
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masterThesis -
192
An adaptive load-balancing approach to XML-based network management using JPVM
منشور في 2005"…In this paper, we propose a framework for adaptive load-balancing using JPVM for XML-based network management. The goal is to increase the efficiency of processing the management data, and decrease the communication time by distributing the management load across multiple XML/SNMP gateways. …"
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193
A Comprehensive Method of Ion Exchange Resins Regeneration and Its Optimization for Water Treatment
منشور في 2020"…Water conductivity, as an indicator of regeneration efficiency, was monitored over time at the different conditions and scenario. In general, it was observed that the conductivity decreases with time until one point is reached and then starts to increase as a result of resin saturation. …"
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bookPart -
194
Malva pseudolavatera Leaf Extract Promotes ROS Induction Leading to Apoptosis in Acute Myeloid Leukemia Cells In Vitro
منشور في 2020"…Treatment of AML cell lines with M. pseudolavatera methanolic leaf extract showed a dose- and time-dependent inhibition of proliferation and a dose-dependent increase in apoptotic hallmarks such as an increase in phosphatidylserine on the outer membrane leaflet and membrane leakage in addition to DNA fragmentation. …"
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article -
195
Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
منشور في 2023"…</p><h3>Conclusion</h3><p dir="ltr">To our knowledge this is the first report of the stable non-lethal increase of SLFN11 expression in a cancer cell line. …"
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196
The antioxidant and anticancer effects of Wild Carrot oil extract
منشور في 2012"…The effect of DCOE on the cell lines exhibited time and dose-dependent responses. …"
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article -
197
Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes
منشور في 2023"…However, we did not observe the same changes in the other KO lines. …"
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198
Human recombinant arginase I(Co)-PEG5000 [HuArgI(Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human acute myeloid leukemia cells
منشور في 2013"…Addition of l-citrulline led to the rescue of five cell lines. The four cell lines that were not rescued by l-citrulline did not express argininosuccinate synthetase-1, indicating complete arginine auxotrophy. …"
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199
A comprehensive design and rating study of evaporative coolers and condensers. Part I. Performance evaluation
منشور في 2020"…Furthermore, it is noted that there is about 4.7% increase in outlet process fluid temperature of the evaporative fluid cooler. …"
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200
Brain Connectivity Analysis Under Semantic Vigilance and Enhanced Mental States
منشور في 2019"…The audio stimulation enhances the connectivity network over the frontal and parietal regions and the right hemisphere. The increase in the connectivity network correlates with individual differences in the magnitude of the vigilance enhancement assessed by response time to stimuli. …"
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article