Synergistic Effect of Epigenetic Inhibitors Decitabine and Suberoylanilide Hydroxamic Acid on Colorectal Cancer In vitro حسب Najem, Sonia A.

"…Objective: In this study, we evaluated the effect of Suberoylanilide Hydroxamic Acid (SAHA), a panhistone deacetylase inhibitor, and Decitabine (DAC), a DNA methyltransferase inhibitor, either alone or in combination, on Caco-2 human colon cancer cell line in vitro. Results: Our results showed that SAHA and DAC, separately, significantly decreased cell proliferation, induced apoptosis and cell cycle arrest of Caco-2 cell line. …"
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Impact of abiraterone on patient-related outcomes in metastatic castration-resistant prostate cancer حسب El-Amm, Joelle

"…Abiraterone acetate has established a major role in the treatment paradigm of metastatic castration-resistant prostate cancer ever since pivotal trials, COU-AA-301 and COU-AA-302, have shown benefit in both the second-line and first-line (post- and pre-chemotherapy) setting, respectively, with improvement in overall survival as well as secondary end points such as prostate-specific antigen (PSA) and radiographic response rates, time to PSA progression, and progression-free survival. …"
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Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 حسب Natalia V, Bhattacharjee

"…Additionally, the distribution of livebirths across the globe is shifting, with a greater proportion occurring in the lowest-income countries. …"
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Squamous Cell Carcinomas of the Head and Neck Cancer Response to Programmed Cell Death Protein-1 Targeting and Differential Expression of Immunological Markers: A Case Report حسب Maysaloun Merhi (4246147)

"…His NY-ESO-1 antibody was found to be lower after the third (****p < 0.0001) and the fifth (****p < 0.0001) cycles of treatment compared to base line, and this was in line with the stability of the disease. …"

Implementation of trust region methods in optimization. (c1998) حسب Hajj, Mohammed Omar

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Network Threat Detection Using Machine/Deep Learning in SDN-Based Platforms: A Comprehensive Analysis of State-of-the-Art Solutions, Discussion, Challenges, and Future Research Dir... حسب Naveed Ahmed (2433958)

"…Finally, we focus on the opportunities and difficulties that lie ahead for future research on SDN-based ML and DL for NIDS.…"

The changing landscape in the treatment of metastatic castration-resistant prostate cancer حسب El Amm, Joelle

"…The past few years have brought increasing advances in the therapeutic management of metastatic castration-resistant prostate cancer with the approval of several agents, including vaccine therapy with sipuleucel-T, second-line chemotherapy with cabazitaxel, the bone-targeted pharmaceutical denosumab, and the novel antiandrogen therapy abiraterone acetate. …"
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The Effect of HuArgI (Co)-PEG5000 on The Migration of Ovarian Cancer حسب El Mais, Nour

"…Finally, we looked at the effect of HuArgI (Co)-PEG5000 on 3D motility of the ovarian cancer cell line, using a collagen based assay. It showed that SKOV3 cell line does not show significant invasiveness to collagen. …"
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Osteoporosis: An under-recognized public health problem حسب Rajasree Vijayakumar (19807284)

"…It highlights risk factors such as age, sex, genetic background, and other under lying illnesses (factors that are generally “non-modifiable”). …"

Adoption and Implementation of Online Learning Systems in Lebanon: Prospects and Barriers حسب SHAYA, NESSRIN MOHAMMAD

"…A multiple case study, mixed-methods research design, was conducted on Lebanese higher education students, faculty and senior academic leaders, revealed adequate readiness levels and increased acceptance of online education among students and faculty. …"
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Emerging therapies in multiple myeloma حسب El-Amm, Joelle

"…However, despite the increased effectiveness of the first-line agents, the majority of patients will eventually relapse and become drug resistant. …"
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Ultrasonically Triggered Release of Folic Acid-Conjugated Liposomes for Breast Cancer Therapy Within Microfluidic Devices حسب AlHazaimeh, Taima Khair Alla

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Emerging Glycation-Based Therapeutics—Glyoxalase 1 Inducers and Glyoxalase 1 Inhibitors حسب Naila Rabbani (291722)

"…In the National Cancer Institute human tumor cell line screen, BBGD was most active against the glioblastoma SNB-19 cell line. …"

PRAME promotes epithelial-to-mesenchymal transition in triple negative breast cancer حسب Ghaneya Al-Khadairi (14153274)

"…Gene ontology analyses revealed enrichment of genes that are dysregulated in ovarian and esophageal cancer and are involved in transcription and apoptosis. In line with this, interrogation of TCGA and GTEx data demonstrated an increased PRAME expression in ovarian and esophageal tumor tissues in addition to breast tumors where it is associated with worse survival. …"

Modeling and Performance Analysis of mmWave and WiFi-Based Vehicle Communications حسب Mohamed Rjab (21393908)

"…This study explores a comparative analysis of mmWave and WiFi transmission technologies, with a specific focus on line-of-sight (LoS) and non-line-of-sight (NLoS) scenarios in both 2D and 3D modeling environments. …"

3D FEM Model on the Parameters’ Influence of EPB-TBM on Settlements of Single and Twin Metro Tunnels During Construction حسب Masoud Forsat (14158980)

"…<p>The present research exposes the investigation on three-dimensional modeling of the single and twin metro tunnels for the case of the Tehran metro line. At first, simulation implemented on the comparison of the ground movements in the single and twin tunnels. …"

Lyapunov-Function-Based Controller for Single-Phase NPC Quasi-Z-Source Inverter with 2<em>ω</em> Frequency Ripple Suppression حسب Sertac Bayhan (16388511)

"…Furthermore, the modified simple boost control technique is proposed to eliminate the double-line frequency ripples in the quasi-impedance source inductor currents and minimize the double-line frequency ripples in the quasi-impedance source capacitor voltages. …"

The history and development of newspaper electronic pagination systems in the United States, 1975-1987 حسب Beyrouti, Nouri

"…This was perhaps, due to the unevenness with which the total pagination process has developed, and the continuing problems involved in merging line-art and graphics with text. Increased computer storage space and other advances may solve this problem soon, and satellite transmission of graphic art for national advertisements, to specific newspapers is a new development being planned for the near future.…"
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Marketing communications حسب Beyrouti, Nouri

"…Sponsorship has become increasingly popular - within companies that operate in consumer markets. …"
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Analysing the State of Inclusive Education in China: Challenges and Perspectives حسب Zainab Merchant

"…Key recommendations include ongoing monitoring, clear policy directives, increased family involvement, and enhanced teacher training. …"
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