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Exendin-4 promotes GSIS without increasing β-cell number through upregulation of glucose-sensing apparatus and mitochondrial oxidative phosphorylation machinery genes in hPSC-deriv...
Published 2023“…This consists of 6 stages: S1, definitive endoderm; S2, gut tube endoderm; S3, pancreatic progenitors 1; S4, pancreatic progenitors 2; S5, endocrine precursors; and S6, β-like cells. To determine the differentiation efficiency, relevant stage-specific marker expression was assessed at each stage using flow cytometry. …”
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Violent Extremism Prevention in the Era of Globalization
Published 2020Get full text
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Blood flow restriction‐enhanced platelet‐rich plasma: A pilot randomised controlled trial protocol
Published 2025“…<h3>Purpose</h3><p dir="ltr">To assess platelet‐rich plasma (PRP) changes in platelet and leucocyte count, insulin‐like growth factor 1 (IGF‐1), and interleukin 6 (IL‐6) concentration after bilateral low‐load knee extensions under blood flow restriction (BFR).…”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…In this study we recorded maximum increase in total PP2A at 3 µM sodium selenate in a neuron cell line. …”
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Exploring beyond numeric weight loss: The metabolic effects of semaglutide
Published 2025“…<p dir="ltr">The global burden of overweight and obesity has increased by threefold since the 1970s, which led to increased incidences of cardiovascular disease and <u>type 2 diabetes</u>. …”
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Non-invasive systemic viral delivery of human alpha-synuclein mimics selective and progressive neuropathology of Parkinson’s disease in rodent brains
Published 2023“…This approach is based on the use of a new generation of adeno-associated virus (AAV), AAV-PHP.eB, with an increased capacity to cross the blood-brain barrier, thus offering a viable tool for a non-invasive and large-scale gene delivery in the central nervous system.…”
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Fluid Administration in Emergency Room Limited by Lung Ultrasound in Patients with Sepsis: Protocol for a Prospective Phase II Multicenter Randomized Controlled Trial
Published 2020“…Thus, B lines seen by bedside ultrasound may have a role in guiding fluid therapy.…”
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Shear performance of FRP Reinforced Deep Beams Made of Ultra High Performance Concrete (UHPC)
Published 2023Get full text
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Immunomodulatory effects of tumor Lactate Dehydrogenase C (LDHC) in breast cancer
Published 2025“…Silencing LDHC in breast cancer cell lines (MDA-MB-468, BT-549, HCC-1954) enhanced early T cell activation and cytolytic activity. …”
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"Development of Authentic Annual and Seasonal Lightning Thunderstorms Day Maps for Saudi Arabia"
Published 2006“…The southern region in general, and especially the cities of Abha, Taif and Al-Baha, has shown greater numbers of thunderstorm days all year round. …”
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"Thunderstorm distribution and frequency in Saudi Arabia"
Published 2005“…The southern region in general, and especially the cities of Abha, Taif and Al-Baha, has shown greater numbers of thunderstorm days all year round. …”
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Visitors off the trail: Impacts on the dominant plant, bryophyte and lichen species in alpine heath vegetation in sub-arctic Sweden
Published 2021“…With a greater decrease in taller forbs and shrubs than in graminoids and prostrate plants, a greater decrease in lichen than in bryophyte species, and a change in vegetation composition. …”
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Evidence-based safety education and training for traffic injury prevention
Published 2015“…Bicycle skill training for children and youth may increase their safety knowledge, but not necessarily improve their behavior or decrease their injury rates. …”
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Gaining or Losing Team Ball Possession: The Dynamics of Momentum Perception and Strategic Choice in Football Coaches
Published 2019“…Nonetheless, both variables displayed asymmetrical effects, in the sense that: (1) the strength of positive PM appeared to be easier to decrease than to increase; and (2) the greater the positive PM (or the negative PM), the lesser (or the greater) the coaches’ tendency to make a change in the organization of their teams. …”
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Rebound effects undermine carbon footprint reduction potential of autonomous electric vehicles
Published 2023“…However, they are likely to increase road transport activity and life cycle greenhouse emissions, due to several rebound effects. …”