Water-pipe smoking promotes epithelial–mesenchymal transition and invasion of human breast cancer cells via ERK1/ERK2 pathways by Khaled W. Sadek (14153196)

“…<p>With the increasing popularity of water-pipe smoking (WPS), it is critical to comprehend how WPS may affect women’s health. …”

Alterations in blood Lipoprotein & Apolipoprotein B profile induced by moderate acute & chronic alcohol intake in the rat model. (c2002) by Berberi, Rania

“…Therefore, despite reported correlations between the obtained increases in chylomicron and VLDL plasma concentrations and atherogenesis, this study suggests that the reduced amount of cholesterol per newly secreted VLDL particle and their increased catabolic rate will ultimately lead to a reduced total and LDL cholesterol concentrations in the fasted state. …”
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The protective role of lidocaine in surgeries involving trigeminal nerve manipulation: a meta-analysis of trigeminocardiac reflex prevention by Almonzer Al-Qiami (22393303)

“…This leads to a rapid increase in parasympathetic activity, resulting in a decrease in heart rate (HR) and blood pressure, which can potentially lead to bradycardia, and cardiac arrest, with a prevalence of 14.5% during neurointerventional procedures (8). …”

Ambulatory general urgent clinic: an initiative at the time of COVID-19 pandemic by Abdullah Al-Hothi (18505290)

“…Our quality improvement study aimed to decrease the waiting time by 20%, from 21 days in January 2021 to 14 days in April 2021, to evaluate the newly established clinics for urgent referrals during the COVID-19 pandemic, and to assess the physicians’ satisfaction regarding these clinics.…”

Women’s empowerment as a determinant of neonatal mortality in Sub-Saharan Africa: a narrative review focused on Nigeria by Joel-Medewase Victor Idowu (22155178)

“…Notably, SSA and South Asia are the regions most lagging behind the Sustainable Development Goal (SDG) 3.2, aiming for <12 neonatal deaths per 1,000 live births by 2030. Within SSA, Nigeria, the most populous country, records the highest number of neonatal deaths annually. …”

Comparative Study on Beneficial Effects of Hydroxytyrosol- and Oleuropein-Rich Olive Leaf Extracts on High-Fat Diet-Induced Lipid Metabolism Disturbance and Liver Injury in Rats by Ines Fki (14571855)

“…Equally, it showed a rise of the apoptotic markers (a decrease in the expression of the Bcl-2 and an increase of the P53). …”

Cost-Benefit Analysis of Antimicrobial Stewardship Program in the Adult General Medicine Setting in Qatar by Dina Abushanab (10696501)

“…</p><h3> Results</h3><p dir="ltr">The operational costs of the program decreased with maturity by cost savings of QAR125 per 100-patient beds per year. …”

Phospho-MEK1/2 and uPAR Expression Determine Sensitivity of AML Blasts to a Urokinase-Activated Anthrax Lethal Toxin (PrAgU2/LF) 1 by Nasser, Selim

“…PrAgU2/LF was cytotoxic to five out of nine AML cell lines. Cytotoxicity of PrAgU2/LF appeared to be nonapoptotic and was associated with MAPK activation and urokinase activity because all the PrAgU2/LF-sensitive cell lines showed both uPAR expression and high levels of MEK1/2 phosphorylation. …”
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Global, regional and national burden of bladder cancer and its attributable risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of... by Saeid Safiri (3713035)

“…Age-standardised death rate decreased by 15.7% (8.6 to 21.0), during the period 1990–2019. …”

Behavior Of Reinforced Concrete Columns Embedded with PET Bottles Under Concentric Axial Compression by Al Bayati, Sadiq Duraid

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Unsustainability in emergent systems by Haddad, Marc

“…In this paper we present a detailed case study of the passenger road transport system in the Greater Beirut Area (GBA) where we identify the root causes of the major problems facing the system today and over the long-term. …”
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Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways by Shehaby, Wassim N.

“…Flow cytometric analysis indicated that both fractions induced sub-G1 phase accumulation and increased apoptotic cell death. Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. …”
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Enhanced cellular uptake and photochemotherapeutic potential of a lipophilic strained Ru(II) polypyridyl complex by Mehanna, Stephanie

“…When compared to cisplatin, the photoproducts were more potent against all tested cell lines, implying that the complex acquired significant chemotherapeutic potential upon irradiation. …”
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Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance by Ajaz A. Bhat (12984701)

“…<p>Early-stage detection of leukemia is a critical determinant for successful treatment of the disease and can increase the survival rate of leukemia patients. The factors limiting the current screening approaches to leukemia include low sensitivity and specificity, high costs, and a low participation rate. …”

PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications by Pramod Darvin (153341)

“…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …”

Hydrophobic Ionic Liquids for Efficient Extraction of Oil from Produced Water by Liaqat, Shehzad

“…The extraction efficiency was found to increase with increasing cation alkyl chain length from C2 to C10. …”
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Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres by Radha, Remya

“…Cytotoxicity assays on human cell lines showed no toxicity towards cells at concentrations of up to 100 µg ml−1 but exhibited increased toxicity at concentrations exceeding 1000 µg ml−1. …”
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Unraveling the future productivity burden of cardiovascular disease in Qatar: Investigating the modifiable risk factors control in type 2 diabetes by Dina Abushanab (10696501)

“…The financial value of PALYs was determined based on the gross domestic product (GDP) per full-time worker (i.e. US$80,573). The base-case model estimated the productivity burden of CVD, and interventional scenarios were simulated to assess potential gains resulting from improved control of modifiable risk factors, including reduced incidence of T2D, lower systolic blood pressure (SBP), decreased number of smokers, and reduced total cholesterol. …”

YOLO-DefXpert: An Advanced Defect Detection on PCB Surfaces Using Improved YOLOv11 Algorithm by Prabu Selvam (22330264)

“…Compared to the standard YOLOv11 model, the proposed YOLO-DefXpert attained an improvement of 9.3% and 13.2% in mAP50 and mAP95, an 11.25% increase in frames per second, and a 69.85MB decrease in model size. …”

Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans by Kirti S. Prabhu (4246144)

“…In addition to cell lines, we assessed the impact of BTZ in an in vivo setting using Caenorhabditis elegans (C. elegans). …”