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181
Modulation of SLFN11 induces changes in DNA Damage response in breast cancer
Published 2023“…</p><h3>Conclusion</h3><p dir="ltr">To our knowledge this is the first report of the stable non-lethal increase of SLFN11 expression in a cancer cell line. …”
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182
The antioxidant and anticancer effects of Wild Carrot oil extract
Published 2012“…The effect of DCOE on the cell lines exhibited time and dose-dependent responses. …”
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183
Growth hormone treatment modulates active ghrelin levels in rats
Published 2014“…Consequently, under such treatment, determination of active ghrelin concentration per tissue mass rather than per tissue protein is favored. …”
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184
Performance assessment of an integrated absorption cooling-hydrogen liquefaction system using geothermal energy
Published 2013“…The results show that the mass of hydrogen gas pre-cooled by the absorption system per unit mass flow rate of geothermal water flowing through the system (n) and the amount of hydrogen liquefied per unit mass flow rate of geothermal water flowing through the system (y) increase with an increase in the geothermal source temperature. …”
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185
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186
Postprandial lipaemia 10 and 34 hours after playing football: Does playing frequency affect the response?
Published 2019“…<p dir="ltr">Elevated postprandial triglyceride (TG) is associated with increased risk of cardiovascular disease. The time window for the last bout beneficial effect on postprandial lipaemia after football play is unknown. …”
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187
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188
An improved non-dimensional model of wet-cooling towers
Published 2020“…The first method shows a maximum decrease of 4.4 per cent in error, whereas in the second method, the maximum error was found to be 3.3 and 6.8 per cent when the inlet air was unsaturated and saturated, respectively. …”
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189
The mechanism of action of kefir and its effect on the motility of breast and colorectal cancer cells. (c2013)
Published 2016“…Western blot assay results confirmed the previously observed increase in apoptosis as it showed an increase in Bax:Bcl-2 expression upon kefir treatment. …”
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190
Comparative Effect of Sodium Butyrate and Sodium Propionate on Ovarian Cancer Migration, Invasion, and Epithelial-To-Mesenchymal Transition
Published 2025“…Methodology: The two ovarian cancer cell lines, SKOV-3 and PA-1, were treated with NaB and NaP for 24h. …”
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masterThesis -
191
Characterization of the potency and mechanism of action of a novel dual-selective intermolecularly complemented version of Anthrax Lethal Toxin (PAU2R200A- PAL1I207R/FP59) in Acute...
Published 2023“…Finally, while IMC/LF treatment did not affect the expression of any of the proteases tested (uPAR, MMP2, and MMP9), treatment with IMC/FP59 did affect their expression with significant cytotoxic responses seen only in cells whose uPAR expression was not affected at any time point post-treatment. In this study, we showed for the first time the potency of IMC PrAg variant on AML cell lines, its mode of action, as well as its mechanism of cell death.…”
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192
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193
Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018)
Published 2018“…The addition of chloroquine, an autophagy inhibitor, increased the sensitivity of cells to [HuArgI (Co)-PEG5000]-mediated arginine depletion at earlier time points. …”
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masterThesis -
194
The Anti-Tumor Effect of Flaxseed Lignan Derivatives on Different Acute Myeloid Leukemia Cancer Cells
Published 2020“…Cytotoxicity assays, using WST-1, revealed dose- and time- dependent effects in various AML cell lines with the most prominent cytotoxicity exhibited by ENL. …”
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195
Kefir induces cell-cycle arrest and apoptosis in HTLV-1-negative malignant T-lymphocytes
Published 2011“…The percent reduction in proliferation was very significant, and was dose-, and time-dependent. In both cell lines, kefir exhibited its antiproliferative effect by downregulating TGF-α and upregulating TGF-β1 mRNA expression. …”
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196
Artificial neural network algorithms. (c1999)
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masterThesis -
197
Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015)
Published 2016“…Furthermore, we have attempted to examine the photochemical potential of our metal-organic compound model by combining L-II and L-III in the same metal complex, thus generating four final complexes with differing net charges (from +2 to -4), and examining their activities on a panel of AML cell lines with or without exposure to blue light. Of the four final complexes Ru-II3, Ru-II2-III, Ru-II-III2 and Ru-III3, only Ru-II3 and Ru-II2-III have shown significant activity against all tested cell lines in the dark, whereas photo-activation against ML2 has shown a marked increase of potency of all four complexes, even those shown to be biologically inert in the dark, reaching IC50 values in the nM range. …”
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198
Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021
Published 2024“…Although the global age-standardised incidence rate of appendicitis has steadily decreased between 1990 and 2021, almost half of GBD regions saw an increase of greater than 10% in their age-standardised incidence rates. …”
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199
Modeling circadian clock–cell cycle interaction effects on cell population growth rates
Published 2014“…Particularly, we show that Cry 1, Cry 2 mutations decrease the growth rate of cells, Per 2 mutation enhances it and Bmal 1 knockout increases it for autonomous periods of the cell cycle less than 21 h and decreases it elsewhere. …”
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200
Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes
Published 2022“…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …”