PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications by Pramod Darvin (153341)

“…PD-L1 promoter was significantly hypomethylated in MCF-7 tumorspheres, but not from BT-549 tumorspheres, compared with their cell line counterparts. The active demethylation of PD-L1 promoter was confirmed by the increase in the distribution of 5hmC and decrease in 5mC levels and the upregulation of TET3 and downregulation of DNMTs enzymes in MCF-7 tumorspheres, compared with the cell line. …”

Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion by Khoury, Nathalie

“…Kefir's anti‑cancer potential was tested on CRC cell lines, Caco‑2 and HT‑29, through cytotoxicity, proliferation, and apoptotic assays. …”
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Modifying cellulose fibres with carbon dots: a promising approach for the development of antimicrobial fibres by Radha, Remya

“…Cytotoxicity assays on human cell lines showed no toxicity towards cells at concentrations of up to 100 µg ml−1 but exhibited increased toxicity at concentrations exceeding 1000 µg ml−1. …”
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I know you are watching me by Abdel Wahab, Omar

“…However, limited security resources prohibit full detection coverage on all VMs at all times, which can be exploited by attackers to examine the selective detection strategies and adjust their own attack plans accordingly. …”
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Riding the waves: A study of retrun spillovers and inter-sector linkages in US equity markets during the COVID-19 pandemic by Umar Kayani (17986576)

“…<p>In times of crisis, stock markets experience a significant increase in return volatility, which leads to spillovers across equity sectors. …”

Optimizing Truck Visits to Container Terminals with Consideration of Multiple Drays of Individual Drivers by Raka Jovanovic (17947838)

“…The objective of this approach is to show that it is possible to increase the satisfaction of drivers which will maintain the positive effects that the TAS provides to the port. …”

Hepatoprotective Effect of Oleuropein-Rich Extract from Olive Leaves against Cadmium-Induced Toxicity in Mice by Hedya Jemai (14571781)

“…(CD), administered five times during two weeks; and the third group received the same doses of Cd and simultaneously 16 mg/kg b.w. of oleuropein. …”

Over-Pressure Suppresses Ultrasonic-Induced Drug Uptake by Stringham, S. Briant

“…Data also showed a linear increase in membrane permeability with respect to insonation time and intensity. …”
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The Identification Process & Tools for Gifted and Talented Students: Research on Five inclusive government schools in Ajman to study the areas of identification process tools utili... by Hersi, Maryam Salem Mohammed Saed

“…With the increase focus on innovation and creativity, the Giftedness Education has become embedded with the UAE government’s future strategies. …”
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Unraveling the future productivity burden of cardiovascular disease in Qatar: Investigating the modifiable risk factors control in type 2 diabetes by Dina Abushanab (10696501)

“…The financial value of PALYs was determined based on the gross domestic product (GDP) per full-time worker (i.e. US$80,573). The base-case model estimated the productivity burden of CVD, and interventional scenarios were simulated to assess potential gains resulting from improved control of modifiable risk factors, including reduced incidence of T2D, lower systolic blood pressure (SBP), decreased number of smokers, and reduced total cholesterol. …”

YOLO-DefXpert: An Advanced Defect Detection on PCB Surfaces Using Improved YOLOv11 Algorithm by Prabu Selvam (22330264)

“…Compared to the standard YOLOv11 model, the proposed YOLO-DefXpert attained an improvement of 9.3% and 13.2% in mAP50 and mAP95, an 11.25% increase in frames per second, and a 69.85MB decrease in model size. …”

Urban Geometry: The Effect of Height Diversity and Buildings Configuration on Thermal Performance and Cooling Load at Urban Scale. A Case Study in Dubai / UAE by SHAREEF, SUNDUS LUAY

“…Furthermore, building orientation plays a significant role in the thermal performance of the urban block, and it contributes to the total cooling load energy saving of the urban block by 6.6 % at the peak time of cooling demand. Moreover, the research found that the variation in building heights will increase the wind velocity by up to 23 %, and this improvement in air flow affects the outdoor air temperature positively. …”
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Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans by Kirti S. Prabhu (4246144)

“…In addition to cell lines, we assessed the impact of BTZ in an in vivo setting using Caenorhabditis elegans (C. elegans). …”

Investigating the Therapeutic Effects of Small Molecule Imipridones In Pediatric Neuroblastoma by El Soussi, Sarra

“…MYCN expression was significantly abrogated in the IMR-32 cell line with either drug treatment. The protein expression of Sox-2, Oct-4, FABP5 and HMGA1 was significantly reduced whereas cleaved PARP1 and caspase-3 and p-H2AX was increased 48 h after drug treatment in the MYCN-amplified IMR-32 cell line. …”
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Urtica dioica extract and its impact on blood lipids, glycemia & inflammation in the rat model. (c2005) by Baroudy, Karmen George

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The impact of COVID‐19 pandemic lockdown on smoking habits and lifestyle: A cross‐sectional study by Almu'atasim Khamees (11875640)

“…While those who had a decrease in their smoking level experienced a somehow healthier lifestyle regarding nutrition and other aspects.…”

Thymoquinone from Nigella sativa seeds promotes the antitumor activity of noncytotoxic doses of topotecan in human colorectal cancer cells in vitro by Khalife, Rana

“…In conclusion, thymoquinone increased the effectiveness of the chemotherapeutic reagent topotecan by inhibiting proliferation and lowering toxicity through p53- and Bax/Bcl2-independent mechanisms.…”
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Free-space-optical communications over turbulent channels. (c2009) by Bkassiny, Mario

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Regulation of visceral sympathetic tone by A5 noradrenergic neurons in rodents by Kanbar, Roy

“…This effect presumably contributes to the increase in visceral sympathetic nerve activity elicited by acute hypoxia. …”
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Effects of electrode morphology on the performance of BPSH and PATS ionic polymer transducers by Akle, Barbar J.

“…The electromechanical coupling in ionomeric materials is due to the charge motion in the polymer backbone. Increasing the capacitance of the actuator increases the motion of the charges and the actuation performance of ionic polymer transducers has been shown to be strongly correlated with charge motion. …”
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