Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015) by Azar, Daniel Fadi

“…Furthermore, we have attempted to examine the photochemical potential of our metal-organic compound model by combining L-II and L-III in the same metal complex, thus generating four final complexes with differing net charges (from +2 to -4), and examining their activities on a panel of AML cell lines with or without exposure to blue light. Of the four final complexes Ru-II3, Ru-II2-III, Ru-II-III2 and Ru-III3, only Ru-II3 and Ru-II2-III have shown significant activity against all tested cell lines in the dark, whereas photo-activation against ML2 has shown a marked increase of potency of all four complexes, even those shown to be biologically inert in the dark, reaching IC50 values in the nM range. …”
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Columbus s.a.r.l. (c1994) by Wehbe, Rani F.

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Global, regional, and national burden of respiratory tract cancers and associated risk factors from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019 by Hedyeh Ebrahimi (7321358)

“…Global age-standardised incidence rates of tracheal, bronchus, and lung cancer decreased by 7·4% (−16·8 to 1·6) and age-standardised incidence rates of larynx cancer decreased by 3·0% (−10·5 to 5·0) in males over the past decade; however, during the same period, age-standardised incidence rates in females increased by 0·9% (−8·2 to 10·2) for tracheal, bronchus, and lung cancer and decreased by 0·5% (−8·4 to 8·1) for larynx cancer. …”

Holistic Transitional Approach of Humanitarian Shelters Through The Implementation of Adaptable Design Strategies. by ALSHALABI, WASEEM

“…The issue of forcibly displaced portions of a population has become an emerging global trend that is driven by significantly increased numbers of displaced people. This is caused by increases in natural disasters due to global warming, war, and other conflicts. …”
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Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2... by Michael, Brauer

“…For younger demographics (ie, those aged 0–4 years and 5–14 years), risks such as low birthweight and short gestation and unsafe water, sanitation, and handwashing (WaSH) were among the leading risk factors, while for older age groups, metabolic risks such as high SBP, high body-mass index (BMI), high FPG, and high LDL cholesterol had a greater impact. From 2000 to 2021, there was an observable shift in global health challenges, marked by a decline in the number of all-age DALYs broadly attributable to behavioural risks (decrease of 20·7% [13·9–27·7]) and environmental and occupational risks (decrease of 22·0% [15·5–28·8]), coupled with a 49·4% (42·3–56·9) increase in DALYs attributable to metabolic risks, all reflecting ageing populations and changing lifestyles on a global scale. …”
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Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 by Natalia V, Bhattacharjee

“…Additionally, the distribution of livebirths across the globe is shifting, with a greater proportion occurring in the lowest-income countries. …”
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Forecasting the effects of smoking prevalence scenarios on years of life lost and life expectancy from 2022 to 2050: a systematic analysis for the Global Burden of Disease Study 20... by Dana, Bryazka

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Global, regional, and national prevalence of adult overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease Study 2021 by Marie, Ng

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Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 by Brittney S Sheena (9715568)

“…HBV-related death rates also decreased, but HBV-related death counts increased as a result of population growth, ageing, and <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/cohort-effect" target="_blank">cohort effects</a>. …”

National-level and state-level prevalence of overweight and obesity among children, adolescents, and adults in the USA, 1990–2021, and forecasts up to 2050 by Marie, Ng

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National-level and state-level prevalence of overweight and obesity among children, adolescents, and adults in the USA, 1990–2021, and forecasts up to 2050 by Marie, Ng

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Mapping geographical inequalities in childhood diarrhoeal morbidity and mortality in low-income and middle-income countries, 2000–17: analysis for the Global Burden of Disease Stud... by Robert C Reiner (5147636)

“…Findings The greatest declines in diarrhoeal mortality were seen in south and southeast Asia and South America, where 54·0% (95% uncertainty interval [UI] 38·1–65·8), 17·4% (7·7–28·4), and 59·5% (34·2–86·9) of units, respectively, recorded decreases in deaths from diarrhoea greater than 10%. …”

Global, regional, and national prevalence of child and adolescent overweight and obesity, 1990–2021, with forecasts to 2050: a forecasting study for the Global Burden of Disease St... by Jessica A, Kerr

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Sources of stress for first year students and their perception of the university employed support services by Messarra, Leila Canaan

“…;The majority of respondents were males between 17 and 20, living with their parents and not regular practitioners of religious activities. Most are full timers with a declared major. All are single with the vast majority not working, and many are sojourners.…”
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Lipid profile in Parkinson's disease: The potential role of brain-derived neurotrophic factor by Mahmoud A. Alomari (14780446)

“…<h3>Background</h3><p dir="ltr">Parkinson's disease is a neurodegenerative disease manifested as increased tremor, bradykinesia, rigidity, and postural instability. …”

The effect of doping MoSe₂ by clusters of noble metals on its adsorption for NH₃ by Ahmad I. Ayesh (10188469)

“…Herein, the magnitude of adsorption energy increases and the adsorption distance deceases for NH₃ gas. …”

On the Detection of Passive Malicious Providers in Cloud Federations by Hammoud, Ahmad

“…Cloud federation has emerged as a new business architecture which aims to help cloud providers cope with the increased waves of demands on their resources and services. …”
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Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019 by Hmwe Hmwe Kyu (8674014)

“…During the same period, LRI episodes and deaths in children younger than 15 years were estimated to have decreased, and the greatest decline was observed for LRI deaths in males younger than 5 years (–70·7% [–77·2 to –61·8]). …”

Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic anal... by Haidong, Wang

“…We computed healthy life expectancy (HALE) using years lived with disability (YLDs) per capita, life tables, and standard demographic methods. …”
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Human recombinant arginase I(Co)-PEG5000 [HuArgI(Co)-PEG5000]-induced arginine depletion is selectively cytotoxic to human acute myeloid leukemia cells by Bekdash, Amira

“…In this study, we target arginine auxotrophy of AML cell lines using human arginase I cobalt-PEG5000. HuArgI(Co)-PEG5000 was cytotoxic to all AML cell lines tested. …”
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